A Carbohydrate Fraction, AIP1, from Artemisia Iwayomogi Reduces the Action Potential Duration by Activation of Rapidly Activating Delayed Rectifier ![]() ![]() |
Park, Won-Sun
(Department of Physiology, Institute of Medical Science, Kangwon National University School of Medicine)
Son, Youn-Kyoung (Department of Physiology, Institute of Medical Science, Kangwon National University School of Medicine) Ko, Eun-A (National Research Laboratory for Mitochondrial Signaling, FIRST Mitochondria Research Group, Department of Physiology and Biophysics, College of Medicine, Cardiovascular and Metabolic Disease Center, Inje University) Choi, Seong-Woo (National Research Laboratory for Mitochondrial Signaling, FIRST Mitochondria Research Group, Department of Physiology and Biophysics, College of Medicine, Cardiovascular and Metabolic Disease Center, Inje University) Kim, Na-Ri (National Research Laboratory for Mitochondrial Signaling, FIRST Mitochondria Research Group, Department of Physiology and Biophysics, College of Medicine, Cardiovascular and Metabolic Disease Center, Inje University) Choi, Tae-Hoon (Department of Sport and Leisure Studies, Andong Science College) Youn, Hyun-Joo (Department of Microbiology and School of Biotechnology & Biomedical Science, Inje University) Jo, Su-Hyun (Department of Physiology, Institute of Medical Science, Kangwon National University School of Medicine) Hong, Da-Hye (National Research Laboratory for Mitochondrial Signaling, FIRST Mitochondria Research Group, Department of Physiology and Biophysics, College of Medicine, Cardiovascular and Metabolic Disease Center, Inje University) Han, Jin (National Research Laboratory for Mitochondrial Signaling, FIRST Mitochondria Research Group, Department of Physiology and Biophysics, College of Medicine, Cardiovascular and Metabolic Disease Center, Inje University) |
1 |
Guerard NC, Traebert M, Suter W, Dumotier BM. Selective block of |
2 | Kim AR, Zou YN, Park TH, Shim KH, Kim MS, Kim ND, Kim JD, Bae SJ, Choi JS, Chung HY. Active components from Artemisia iwayomogi displaying ONOO- scavenging activity. Phytother Res. 2004;18:1-7. DOI ScienceOn |
3 |
Sanguinetti MC, Jiang C, Curran ME, Keating MT. A mechanistic link between and inherited and an acquired cardiac arrhythmia: HERG encodes the |
4 |
Folaander K, Smith JS, Antanavage J, Bennett C, Stein RB, Swanson R. Cloning and expression of the delayed rectifier |
5 | Keating MT, Sanguinetti MC. Molecular and cellular mechanisms of cardiac arrhythmias. Cell. 2001;104:569-580. DOI ScienceOn |
6 | Ji HJ, Yeo HK, Lee NH, Hwang JS, Koo KA, Cheong SW, Park JH, Oh GS, Yoon CS, Youn HJ. A carbohydrate graction, AIP1, from Artemisia iwayomogi down-regulated Fas gene expression and suppresses apoptotic death of the thymocytes induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biotechnol Lett. 2005;27:253-257. DOI ScienceOn |
7 |
Lee JA, Sung HN, Jeon CH, Gill BC, Oh GS, Youn HJ, Park JH. A carbohydrate fraction, AIP1 from Artemisia iwayomogi suppresses pulmonary eosinophilia and Th2-type cytokine production in an ovalbumin-induced allergic asthma. Down- regulation of TNF- |
8 | Ahn H, Kim JY, Lee HJ, Kim YK, Ryu JH. Inhibitors of inducible nitric oxide synthase expression from Artemisia iwayomogi. Arch Pharm Res. 2003;26:301-305. 과학기술학회마을 DOI ScienceOn |
9 | Takumi T, Ohkubo H, Nakanishi S. Cloning of a membrane protein that induced a slow voltage-gated potassium current. Science. 1988;242:1042-1045. DOI |
10 |
Freeman LS, Kass RS. Expression of a minimal |
11 |
Sanguinetti MC, Curran ME, Zou A, Shen J, Spector PS, Atkinson DL, Keating MT. Coassembly of KvLQT1 and mink ( |
12 | Hwang JS, Ji HJ, Koo KA, Lee NH, Yeo HK, Cheong SW, Park JH, Oh GS, Yoon CS, Youn HJ. AIP1, a water-soluble fraction from Artemisia iwayomogi, suppresses thymocyte apoptosis in Vitro and down-regulates the expression of Fas gene. Biol Pharm Bull. 2005;28:921-924. DOI ScienceOn |
13 |
Wang L, Feng Z, Kondo CS, Sheldon RS, Duff HJ. Developmental changes in the delayed rectifier |
14 |
Hansen RS, Olesen SP, Ronn LC, Grunnet M. In vivo effects of the |
15 |
Heath BM, Terrar DA. Protein kinase C enhances the rapidly activating delayed rectifier potassium current, |
16 | Kim NR, Youm JB, Joo H, Kim EY, Han J. Protein kinase C activates ATP-sensitive potassium channels in rabbit ventricular myocytes. Korean J Physiol Pharmacol. 2005;9:187-193. 과학기술학회마을 |
17 |
Park WS, Ko JH, Kim NR, Son YK, Kang SH, Warda M, Jung ID, Park YM, Han J. Increased inhibition of inward rectifier |
18 |
Lengyel C, Iost N, Virag L, Varro A, Lathrop DA, Papp JG. Pharmacological block of the slow component of the outward delayed rectifier current ( |
19 | Chung HK, Bae EK, Ji HJ, Hwang JS, Park DW, Kim EJ, Jung HJ, Choi HJ, Lee DS, Youn HJ. An oligosaccharide fraction from Korean mugwort herb suppresses death of the mouse thymocytes in culture by down-regulating the Fas death receptor gene. Biotechnol Lett. 2003;25:1549-1553. DOI ScienceOn |
20 | Volders PG, Stengl M, van Opstal JM, Gerlach U, Spatjens RL, Beekman JD, Sipido KR, Vos MA. Probing the contribution of IKs to canine ventricular repolarization: Key role for betaadrenergic receptor stimulation. Circulation. 2003;107:2753-2760. DOI ScienceOn |
21 | Kim SH, Choi CH, Kim SY, Eun JS, Shin TY. Anti-allergic effects of Artemisia iwayomogi on mast cell-mediated allegy model. Exp Biol Med. 2005;230:82-88. DOI |
22 |
Sanguinetti MC, Jurkiewicz NK. Two components of cardiac delayed rectifier |
23 |
Zeng J, Laurita KR, Rosenbaum DS, Rudy Y. Two components of the delayed rectifier |
24 |
delayed rectifier potassium current using selective blockers of |
25 |
Heath BM, Terrar DA. The deactivation kinetics of the delayed rectifier components |
26 | Chiang CE, Roden DM. The long QT syndromes: genetic basis and clinical implications. J Am Coll Cardiol. 2000;36:1-12. DOI ScienceOn |
27 |
Salata JJ, Jurkiewicz NK, Wang J, Evans BE, Orme HT, Sanguinetti MC. A novel benzodiazepine that activates cardiac slow delayed rectifier |
28 | Koo KA, Kwak JW, Lee KR, Zee OP, Woo ER, Park HK, Youn HJ. Antitumor and immuno-modulating activities of the polysaccharide fractions from Artemisia selengenesis and Artemisia iwayomogi. Arch Pharm Res. 1994;17:371-374. DOI |
29 | Lee KR, Zee OP, Kwak JH, Kim YS, Park HK, Koo KA, Youn HJ. The polysaccharide fractions of Artemisia species. Korean J Pharmacogn. 1993;24:289-295. |
30 | Park EJ, Nan JX, Kim JY, Kang HC, Choi JH, Lee SJ, Lee BH, Lee JH, Kim YC, Sohn DW. The ethanol-soluble part of a hot-water extract from Artemisia iwayomogi inhibits liver fibrosis induced by carbon tetrachloride in rats. J Pharm Pharmacol. 2000;52:875-881. DOI ScienceOn |
31 | Hwang JS, Chung HK, Bae EK, Lee AY, Ji HJ, Park DW, Jung HJ, Cho CW, Choi HJ, Lee DS, Lee KR, Youn HJ. The polysaccharide fraction AIP1 from Artemisia iwayomogi suppresses apoptotic death of the mouse spleen cells in culture. Arch Pharm Res. 2003;26:294-300. 과학기술학회마을 DOI ScienceOn |
32 |
Ko EA, Han J, Jung ID, Park WS. Physiological roles of |
33 |
Yuan XJ, Wang J, Juhaszova M, Golovina VA, Rubin LJ. Molecular basis and function of voltage-gated |
34 | Platoshyn O, Yu Y, Golovina VA, McDaniel SS, Krick S, Li L, Wang JY, Rubin LJ, Yuan JX. Chronic hypoxia decrease K(V) channel expression and function in pulmonary artery myocytes. Am J Physiol. 2001;280:L801-812. |
![]() |