1 |
Cau J, Hall A. Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways. J Cell Sci 118: 2579−2587, 2005
DOI
PUBMED
ScienceOn
|
2 |
Chandra R, Liddle RA. Cholecystokinin. Curr Opin Endocrinol Diabetes Obes 14: 63−67, 2007
ScienceOn
|
3 |
Clerc P, Coll Constans MG, Lulka H, Broussaud S, Guigne C, Leung-Theung-Long S, Perrin C, Knauf C, Carpene C, Penicaud L, Seva C, Burcelin R, Valet P, Fourmy D, Dufresne M. Involvement of cholecystokinin 2 receptor in food intake regulation: hyperphagia and increased fat deposition in cholecystokinin 2 receptor-deficient mice. Endocrinology 148: 1039−1049, 2007
DOI
PUBMED
ScienceOn
|
4 |
Dormer P, Spitzer E, Frankenberger M, Kremmer E. Erythroid differentiation regulator (EDR), a novel, highly conserved factor I. Induction of haemoglobin synthesis in erythroleukaemic cells. Cytokine 26: 231−242, 2004b
DOI
PUBMED
ScienceOn
|
5 |
Gaudreau P, Quirion R, St-Pierre S, Pert CB. Characterization and visualization of cholecystokinin receptors in rat brain using pentagastrin. Peptides 4: 755−762, 1983
DOI
PUBMED
ScienceOn
|
6 |
Guan XM, Yu H, Van der Ploeg LH. Evidence of altered hypothalamic pro-opiomelanocortin/neuropeptide Y mRNA expression in tubby mice. Brain Res Mol Brain Res 59: 273−279, 1998
DOI
PUBMED
ScienceOn
|
7 |
Hill DR, Shaw TM, Woodruff GN. Species differences in the localization of 'peripheral' type cholecystokinin receptors in rodent brain. Neurosci Lett 79: 286−289, 1987a
DOI
PUBMED
ScienceOn
|
8 |
Ikeda A, Naggert JK, Nishina PM. Genetic modification of retinal degeneration in tubby mice. Exp Eye Res 74: 455−461, 2002
DOI
PUBMED
ScienceOn
|
9 |
Jacobs T, Causeret F, Nishimura YV, Terao M, Norman A, Hoshino M, Nikolic M. Localized activation of p21-activated kinase controls neuronal polarity and morphology. J Neurosci 27: 8604−8615, 2007
DOI
ScienceOn
|
10 |
Mackay IM, Arden KE, Nitsche A. Real-time PCR in virology. Nucleic Acids Res 30: 1292−1305, 2002
DOI
PUBMED
ScienceOn
|
11 |
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10: 417−426, 2002
DOI
PUBMED
ScienceOn
|
12 |
Roberts MR, Srinivas M, Forrest D, Morreale de Escobar G, Reh TA. Making the gradient: thyroid hormone regulates cone opsin expression in the developing mouse retina. Proc Natl Acad Sci U S A 103: 6218−6223, 2006
DOI
ScienceOn
|
13 |
Segovia L, Horwitz J, Gasser R, Wistow G. Two roles for mu-crystallin: a lens structural protein in diurnal marsupials and a possible enzyme in mammalian retinas. Mol Vis 3: 9, 1997
PUBMED
|
14 |
Suzuki S, Mori J, Kobayashi M, Inagaki T, Inaba H, Komatsu A, Yamashita K, Takeda T, Miyamoto T, Ichikawa K, Hashizume K. Cell-specific expression of NADPH-dependent cytosolic 3,5,3'-triiodo-L-thyronine-binding protein (p38CTBP). Eur J Endocrinol 148: 259−268, 2003
DOI
ScienceOn
|
15 |
Kremer H, van Wijk E, Marker T, Wolfrum U, Roepman R. Usher syndrome: molecular links of pathogenesis, proteins and pathways. Hum Mol Genet 15 Spec No 2: R262−270, 2006
DOI
ScienceOn
|
16 |
Hill DR, Campbell NJ, Shaw TM, Woodruff GN. Autoradiographic localization and biochemical characterization of peripheral type CCK receptors in rat CNS using highly selective nonpeptide CCK antagonists. J Neurosci 7: 2967−2976, 1987b
|
17 |
Lee JH, Lee J, Seo GH, Kim CH, Ahn YS. Heparin inhibits NF-kappaB activation and increases cell death in cerebral endothelial cells after oxygen-glucose deprivation. J Mol Neurosci 32: 145−154, 2007
DOI
ScienceOn
|
18 |
Ohlemiller KK, Hughes RM, Mosinger-Ogilvie J, Speck JD, Grosof DH, Silverman MS. Cochlear and retinal degeneration in the tubby mouse. Neuroreport 6: 845−849, 1995
DOI
PUBMED
ScienceOn
|
19 |
Boggon TJ, Shan WS, Santagata S, Myers SC, Shapiro L. Implication of tubby proteins as transcription factors by structure-based functional analysis. Science 286: 2119−2125, 1999
DOI
PUBMED
|
20 |
Friedlander R. Role of caspase 1 in neurologic disease. Arch Neurol 57: 1273−1276, 2000
DOI
PUBMED
ScienceOn
|
21 |
Oshima A, Suzuki S, Takumi Y, Hashizume K, Abe S, Usami S. CRYM mutations cause deafness through thyroid hormone binding properties in the fibrocytes of the cochlea. J Med Genet 43: e25, 2006
DOI
PUBMED
|
22 |
Perche O, Doly M, Ranchon-Cole I. Caspase-dependent apoptosis in light-induced retinal degeneration. Invest Ophthalmol Vis Sci 48: 2753−2759, 2007
DOI
PUBMED
ScienceOn
|
23 |
Crawley JN, Corwin RL. Biological actions of cholecystokinin. Peptides 15: 731−755, 1994
DOI
PUBMED
ScienceOn
|
24 |
Wong ML, Medrano JF. Real-time PCR for mRNA quantitation. Biotechniques 39: 75−85, 2005
DOI
PUBMED
ScienceOn
|
25 |
O'Shea E, Sanchez V, Orio L, Escobedo I, Green AR, Colado MI. 3,4-Methylenedioxymethamphetamine increases pro-interleukin- 1beta production and caspase-1 protease activity in frontal cortex, but not in hypothalamus, of Dark Agouti rats: role of interleukin-1beta in neurotoxicity. Neuroscience 135: 1095−1105, 2005
DOI
PUBMED
ScienceOn
|
26 |
Tang Y, Zhou H, Chen A, Pittman RN, Field J. The Akt proto-oncogene links Ras to Pak and cell survival signals. J Biol Chem 275: 9106−9109, 2000
DOI
PUBMED
ScienceOn
|
27 |
Abe S, Katagiri T, Saito-Hisaminato A, Usami S, Inoue Y, Tsunoda T, Nakamura Y. Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues. Am J Hum Genet 72: 73−82, 2003
DOI
PUBMED
ScienceOn
|
28 |
Bokoch GM. Biology of the p21-activated kinases. Annu Rev Biochem 72: 743−781, 2003
DOI
PUBMED
ScienceOn
|
29 |
Umeda S, Suzuki MT, Okamoto H, Ono F, Mizota A, Terao K, Yoshikawa Y, Tanaka Y, Iwata T. Molecular composition of drusen and possible involvement of anti-retinal autoimmunity in two different forms of macular degeneration in cynomolgus monkey (Macaca fascicularis). FASEB J 19: 1683−1685, 2005
DOI
|
30 |
Katsanis N, Lupski JR, Beales PL. Exploring the molecular basis of Bardet-Biedl syndrome. Hum Mol Genet 10: 2293−2299, 2001
DOI
PUBMED
ScienceOn
|
31 |
Morency MA, Quirion R, Mishra RK. Distribution of cholecystokinin receptors in the bovine brain: a quantitative autoradiographic study. Neuroscience 62: 307−316, 1994
DOI
PUBMED
ScienceOn
|
32 |
Santagata S, Boggon TJ, Baird CL, Gomez CA, Zhao J, Shan WS, Myszka DG, Shapiro L. G-protein signaling through tubby proteins. Science 292: 2041−2050, 2001
DOI
PUBMED
ScienceOn
|
33 |
Schurmann A, Mooney AF, Sanders LC, Sells MA, Wang HG, Reed JC, Bokoch GM. p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis. Mol Cell Biol 20: 453−461, 2000
DOI
PUBMED
ScienceOn
|
34 |
Sells MA, Knaus UG, Bagrodia S, Ambrose DM, Bokoch GM, Chernoff J. Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells. Curr Biol 7: 202−210, 1997
DOI
ScienceOn
|
35 |
Dormer P, Spitzer E, Moller W. EDR is a stress-related survival factor from stroma and other tissues acting on early haematopoietic progenitors (E-Mix). Cytokine 27: 47−57, 2004a
PUBMED
ScienceOn
|
36 |
Gillingwater TH, Wishart TM, Chen PE, Haley JE, Robertson K, MacDonald SH, Middleton S, Wawrowski K, Shipston MJ, Melmed S, Wyllie DJ, Skehel PA, Coleman MP, Ribchester RR. The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells. Hum Mol Genet 15: 625−635, 2006
DOI
PUBMED
ScienceOn
|
37 |
Ikeda S, He W, Ikeda A, Naggert JK, North MA, Nishina PM. Cell-specific expression of tubby gene family members (tub, Tulp1,2, and 3) in the retina. Invest Ophthalmol Vis Sci 40: 2706−2712, 1999
PUBMED
|
38 |
Zapala MA, Hovatta I, Ellison JA, Wodicka L, Del Rio JA, Tennant R, Tynan W, Broide RS, Helton R, Stoveken BS, Winrow C, Lockhart DJ, Reilly JF, Young WG, Bloom FE, Barlow C. Adult mouse brain gene expression patterns bear an embryologic imprint. Proc Natl Acad Sci U S A 102: 10357−10362, 2005
DOI
ScienceOn
|
39 |
Schwartz MW, Porte D, Jr. Diabetes, obesity, and the brain. Science 307: 375−379, 2005
DOI
PUBMED
ScienceOn
|
40 |
Wang Y, Barbacioru C, Hyland F, Xiao W, Hunkapiller KL, Blake J, Chan F, Gonzalez C, Zhang L, Samaha RR. Large scale real-time PCR validation on gene expression measurements from two commercial long-oligonucleotide microarrays. BMC Genomics 7: 59, 2006
DOI
PUBMED
ScienceOn
|
41 |
Stubdal H, Lynch CA, Moriarty A, Fang Q, Chickering T, Deeds JD, Fairchild-Huntress V, Charlat O, Dunmore JH, Kleyn P, Huszar D, Kapeller R. Targeted deletion of the tub mouse obesity gene reveals that tubby is a loss-of-function mutation. Mol Cell Biol 20: 878−882, 2000
DOI
PUBMED
ScienceOn
|
42 |
Suzuki S, Mori J, Hashizume K. Mu-crystallin, a NADPH- dependent T(3)-binding protein in cytosol. Trends Endocrinol Metab 18: 286−289, 2007
DOI
ScienceOn
|
43 |
Orio L, O'Shea E, Sanchez V, Pradillo JM, Escobedo I, Camarero J, Moro MA, Green AR, Colado MI. 3,4-Methylenedioxymethamphetamine increases interleukin-1beta levels and activates microglia in rat brain: studies on the relationship with acute hyperthermia and 5-HT depletion. J Neurochem 89: 1445−1453, 2004
DOI
PUBMED
ScienceOn
|
44 |
Bode C, Wolfrum U. Caspase-3 inhibitor reduces apototic photoreceptor cell death during inherited retinal degeneration in tubby mice. Mol Vis 9: 144−150, 2003
PUBMED
ScienceOn
|
45 |
Hing H, Xiao J, Harden N, Lim L, Zipursky SL. Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila. Cell 97: 853−863, 1999
DOI
PUBMED
ScienceOn
|
46 |
Koritschoner N, Alvarez-Dolado M, Kurz S, Heikenwalder M, Hacker C, Vogel F, Munoz A, Zenke M. Thyroid hormone regulates the obesity gene tub. EMBO Rep 2: 499−504, 2001
PUBMED
ScienceOn
|
47 |
Coleman DL, Eicher EM. Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse. J Hered 81: 424−427, 1990
ScienceOn
|
48 |
Kleyn PW, Fan W, Kovats SG, Lee JJ, Pulido JC, Wu Y, Berkemeier LR, Misumi DJ, Holmgren L, Charlat O, Woolf EA, Tayber O, Brody T, Shu P, Hawkins F, Kennedy B, Baldini L, Ebeling C, Alperin GD, Deeds J, Lakey ND, Culpepper J, Chen H, Glucks-mann-Kuis MA, Carlson GA, Duyk GM, Moore KJ. Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family. Cell 85: 281−290, 1996
DOI
PUBMED
ScienceOn
|