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Antifungal Activities of Essential Oil from the Roots of Angelica dahurica Bentham et Hooker f.  

Rho, Junghyun (College of Pharmacy, Duksung Women's University)
Shin, Eunji (College of Pharmacy, Duksung Women's University)
Shin, Seungwon (College of Pharmacy, Duksung Women's University)
Publication Information
YAKHAK HOEJI / v.58, no.1, 2014 , pp. 58-61 More about this Journal
Abstract
The essential oil was extracted from the roots of Angelica dahurica Bentham et Hooker f. by steam distillation and its composition was analyzed by GC-MS. The antifungal activities were evaluated by micro-dilution method against five Aspergillus and three Trichophyton species. The most abundant component was ${\alpha}$-pinene (17.21%) among 40 compounds identified in this oil. The essential oil fraction of A. dahurica and ${\alpha}$-pinene exhibited marked inhibiting activities against the tested Aspergillus and Trichophyton species with MICs (minimum inhibitory concentrations) between 0.12 mg/ml and 8 mg/ml.
Keywords
essential oil; Angelica dahurica; ${\alpha}$-pinene; Aspergillus; Trichophyton;
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