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Establishment of Library for the Identification of Corticosteroids in Various Known Sample Types  

Park, Mee-Jung (Eastern District office, National Forensic Service)
Hong, Hyo-Jeong (Division of Drug and Toxicology Section, National Forensic Service)
Lee, Sang-Ki (Division of Drug and Toxicology Section, National Forensic Service)
Publication Information
YAKHAK HOEJI / v.55, no.4, 2011 , pp. 289-294 More about this Journal
Abstract
Illegal addition of steroids into cosmetics, ointments or drugs have been increased and their careless usage induced detrimental effect on health. We developed simultaneous analytical method using TLC, HPLC and LC/MS for the identification of 40 corticosteroids. 34 corticosteroids were well separated in HPLC with isocratic mode and remaining 6 drugs were also separated with gradient mode. All of the 40 corticosteroids were detected in negative mode in LC/MS. Halcinonide, prednisolone, triamcinolone acetonide and methylprednisolone hemisuccinate were detected in real samples.
Keywords
corticosteroids; TLC; HPLC; LC/MS;
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