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Cost-Utility Analysis of Bosentan Versus Iloprost in Korean Patients with Pulmonary Arterial Hypertension  

Sohn, Hyun-Soon (College of Pharmacy, Sookmyung Women's University)
Lee, Tae-Jin (School of Public Health, Seoul National University)
Publication Information
YAKHAK HOEJI / v.54, no.2, 2010 , pp. 126-133 More about this Journal
Abstract
This study was conducted to analyze cost-utility of bosentan versus iloprost indicated for pulmonary arterial hypertension (PAH) in a Korean healthcare setting from a payer's perspective. We constructed a Markov model to estimate total costs and outcomes for 1-year time horizon in a hypothetical cohort of 50-year-old patients with PAH. Base analysis showed that bosentan resulted in KW 5.5 billions saving and 18 quality-adjusted life year (QALY) gains per 100 patients compared to iloprost. Bosentan as a dominant strategy was found to be robust through various sensitivity analyses.
Keywords
cost-effectiveness; cost-utility; pulmonary arterial hypertension; bosentan; iloprost;
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Times Cited By KSCI : 1  (Citation Analysis)
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