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Study on Activities of the Essential Oil from Elsholtzia ciliata against Some Antibiotic-Susceptible and -Resistant Strains of Pathogenic Bacteria  

Shin, Seung-Won (College of Pharmacy, Duksung Women's University)
Publication Information
YAKHAK HOEJI / v.54, no.2, 2010 , pp. 122-125 More about this Journal
Abstract
The essential oil fraction was extracted from the aerial parts of the plant by steam distillation method and its composition was analyzed by GC-MS (gas chromatography-mass spectrometry) which led to the identification of 43 compounds. Dehydroelsholtzia ketone (56.81%) and elsholtzia ketone (30.05%) were identified as the predominant components of this oil. The antibacterial activities of the essential oil fraction were assessed by micro-dilution tests against antibioticsusceptible and -resistant strains of Streptococcus pneumoniae, Staphylococcus aureus, Salmonella enteritidis, and S. typhimurium. The oil inhibited most of the tested strains significantly resulting MICs (minimum inhibiting concentrations) between 2 mg/ml and >16 mg/ml. In most cases of this study Streptococcus pneumoniae and Staphylococcus aureus showed higher sensitivity to this oil than Salmonella strains.
Keywords
essential oil; Elsholtzia ciliata; antibiotic-resistance; elsholtzia ketone; dehydroelsholtzia ketone; Streptococcus pneumoniae; Staphylococcus aureus; Salmonella enteritidis; S. typhimurium;
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Times Cited By KSCI : 2  (Citation Analysis)
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1 Clinical and Laboratory Standards Institute : Performance standards for antimicrobial susceptibility testing; seventh informational supplement 27, pp. 98-114. Suit, USA (2007).
2 Ito, M. and Honda, G. : Geraniol synthases from perilla and their taxonomical significance. Phytochemistry 68, 446 (2007).   DOI   ScienceOn
3 Kobold, U., Vostrowsky, O, Bestmann, H. J., Bisht, J. C., Pant, A. K., Melkani, A. B. and Mathcla, C. S. : Terpenoids from Elsholtzia species; II. Constituents of essential oil from a new chemotype of Elsholtzia cristata. Planta Med. 53, 268 (1987).   DOI   ScienceOn
4 Weyerstahl, P. and Shultze, M. : Structure-odour correlation, part XIV: Aldol reaction of acyl furans to $\alpha$, $\beta$-unsaturated furanyl ketones (naginata ketone analogues) and their olfactive properties. Flavour Frag. J. 6, 171 (1991).   DOI
5 Singh, B. R., Singh, P., Agrawal, S., Teotia, U., Verma, A., Sharma, S., Chandra, M., Babu, N. and Kant Agarwal, R. : Prevalence of multidrug resistant Salmonella in Coriander, mint, carrot, and radish in Bareilly and Kanpur, northern India. Foodb. Path. Dis. 4, 233 (2007).   DOI   ScienceOn
6 Choi, H. S. and Min, K. C. : Aroma-active compounds of Elsholtzia splendens using AEDA and HS-SPME-GC-O dilution analysis. Flavour Frag. J. 23, 58 (2008).   DOI   ScienceOn
7 Liu, C., Chang, C. and Chou, T. : A novel synthesis of cisdihydro-rose oxide and related stereochemistry. J. Heterocycl. Chem. 21. 129 (1984).   DOI
8 Chung, E. Y., Byun, Y. H., Shin, E. J., Chung, H. S., Lee, Y. H. and Shin, S. : Antibacterial effects of vulgarone B from Artemisia iwayomogi alone and in combination with oxacillin. Arch. Pharm. Res. 32, 1711 (2009).   과학기술학회마을   DOI   ScienceOn
9 Chi, H. J., Shin, S. and Chang, J. I. : Analysis f essential oils from Elsholtzia ciliata and the production of essential oils by tissue cultures. Kor. J. Pharmacog. 23, 77 (1992).
10 이창복 : 한국식물도감. 향문사 서울 p. 660 (1986).
11 Foley, S. L. and Lynn, A. M. : Food animal-associated Salmonella challenges: Pathogenicity and antimicrobial resistance. J. Animal Sci. 86, 173 (2008).
12 Byun, Y. H. and Shin, S. : Analysis of composition and activity of essential oil from Chrysanthemum zawadskii var. latilobum and C. indicum against antibiotic-resistant pathogenic bacteria. Nat. Prod. Sci. 14, 138 (2008).   과학기술학회마을
13 Kikuchi, K. : VRE, VRSA. Japan. J. Clin. Med. 65, 423 (2007).
14 Hald, T., Lo, F. W., Danilo, M. A. and Aarestrup, F. M. : The attribution of human infections with antimicrobial resistant salmonella bacteria in Denmark to sources of animal origin. Foodb. Path. Dis. 4, 313 (2007).   DOI   ScienceOn
15 Zhanel, G. G., Voth, D., Nichol, K., Karlowsky, J. A., Noreddin, A. M. and Hoban, D. J. : Pharmacodynamic activity of ceftobiprole compared with vancomycin versus methicillinresistant Staphylococcus aureus (MRSA), vancomycinintermediate Staphylococcus aureus (VISA) and vancomycinresistant Staphylococcus aureus (VRSA) using an in vitro model. J. Antimicrob. Chemother. 64, 364 (2009).   DOI   ScienceOn
16 Zhao, S., McDermott, P. F., White, D. G., Qaiyumi, S., Friedman, S. L., Abbott, J. W., Glenn, A., Ayers, S. L., Post, K. W., Fales, W. H., Wilson, R. B., Reggiardo, C. and Walker, R. D. : Characterization of multidrug resistant Salmonella recovered from diseased animals. Veter. Microbiol. 123, 122 (2007)   DOI   ScienceOn