The Preventive Effects of Lycii fructus Extract Against LPS-induced Acute Hepatotoxicity
![]() |
Kang, Kum-Suk
(Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University)
Kwon, Ryun-Hee (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University) Kim, In-Deok (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University) Lee, Dong-Geun (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University) Lee, Jae-Hwa (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University) Lee, Sang-Hyeon (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University) Ha, Jong-Myung (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University) Ha, Bae-Jin (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University) |
1 | Jian, Y. : Modern Study of Chinese Drugs, Clinical Applications. Ancient Book Press of Chinese Medicine, China (1997) |
2 | Finkelstein, J. D., Kyle, W. E. and Harris, B. J. : Methionine metabolism in mammals. Regulation of homocysteine methyl-transferases in rat tissue. Arch. Biochem. Biophys. 146, 84 (1971) |
3 | Kim, H. S., Park, Y. S. and Kim, C. I.: Changes of serum lipid profiles after eating Lycii Fructus in rats fed high fat diet. Korean Nutr. Soc. 31, 263 (1998) |
4 | Kinght, J. A. : The process and theories of aging. Ann. Clin. Lab. Sci. 25, 2289 (1995) |
5 | Lowry, O. H., Rosenbrough, N. J., Farr, A. S. and Randall, R. J.: Protein Measurenment with Folin phenol reagent. J. Biol. Chem. 193, 256 (1951) |
6 | Lawrence, R. A. and Burk, R. E : Glutathione peroxidase activity in selenium-deficient rat liver. Biochem. Biophys. Res. Commun. 71, 952 (1976) |
7 | Gabriel, L. R and William, R. H. : Principles and Methods of Toxicology. Raben Press, p. 407 (1982) |
8 | Rosen, D. R., Jakobisiak, M., Hartmann-Petersen, R., Ortega, S. and Johnston, D. J. : Mutations with familial amyotrophic lateral sclerosis. Nature 362, 59 (1993) |
9 | Gutteridge, J. M. C, Beard, A. P. C. and Quinlan, G. J. : Superoxide-dependent lipid peroxidation. Problem with the use of catalase as a specific probe for Fenton-derived hydroxyl radicals. Biochem. Biophys. Res. Commun. 117, 901 (1983) |
10 | Von, Sonntag. : In The Chemical Basis of Radiation of biology, Tylor and Francis. (ed.). London, p. 31 (1987) |
11 | Yosjikawa, T., Murakami, M., Yoshida, N., Seto, O. and Kondo, M. : Effects of superoxide dimutase and catalase on disseminated intravascular coagulation in rats. Thromb. Haemostas. 50, 869 (1983) |
12 | 조명행 : 기초 독성학, 개정판, 영지문화사, 서울 p. 116 (2004) |
13 | Park, K. M., Hwang, J. K., Shin, K. M., Kim, H. S. and Song, J. H.: Detoxicating effects of oriental herb extract mixtures on nicotine and dioxin. Korean J. Food Sci. Technol. 35, 980 (2003) |
14 |
Takaharu, N. and Kiyonori, Y. : Low-dose |
15 | Yubin, J. : Pharmacological Action : Application of available composition of traditional Chinese medicine. Heilongjiang Science and Technology Press, Heilongjiang (1995) |
16 | Ha, B. J., Lee, S. H., Kim, H. J. and Lee, J. Y. : The role of salicornia herbacea in ovariectomy-induced oxidative stress. Biol. Pharm. Bull. 29, 1306 (2006) |
17 | Aebi, H. : Catalase in vitro, methods. Enzymology 105, 121 (1984) |
18 | 김희선, 박영숙, 김창임 : 구기자 섭취에 의한 고지방식이를 하는 흰쥐의 혈중 지질상태 변화. 한국영양학회지 31, 263 (1998) |
19 | Yoon, C. K., Kim, H. H., Chae, S. N., Oh, M. J. and Lee, G. H.: Hepatic oxygen free radical and alcohol metabolizing enzyme activities in rats fed diets supplementes with Lycium chinense ethanol extract. J. Korean Soc. Food Sci. Nutr. 30, 668 (2001) |
20 | Fridovich, I.: Biologic effects of the superoxide radicals. Arch. Biochem. Biophysm. 247, 1 (1986) |
21 | Kim, N. J., Youn, H. G. and Hong, N. D. : Pharmacological effects of Lycium chinensis. Korean Soc. Pharmacog. 25, 264 (1994) |
22 | Kang, K. I., Jung, J. Y., Koh, K. H. and Lee, C. H. : Hepetoprotective effects of Lycium chinense Mill fruit extracts and fresh fruit juice. Korean J. Food Sci.Technol. 38, 99 (2006) 과학기술학회마을 |
23 | Charles, A. J. : Immunobiology, 5th, Life Science Publication Co, Seoul p. 76 (2002) |
24 | Cho, J. H., Sin, J. S., Km, E. J., Shin, S. H., Jang, J. Y., Shin, K. S., Kim, Y. B., Kang, J. K. and Hwang, S. Y. : Protective effect of Lycii fructus extract against hepatotoxicity induced by carbon tetrachloride. Korean J. Lab. Ani. Sci. 20, 187 (2004) |
25 | McPhalen, C. A., Vincent, M. G. and Jansonius, J. N. : X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase. J. Mol. Biol. 225, 495 (1992) |
26 | Tainer, J. A., Getzoff, E. D., Richardson, J. S. and Richardson, D. C. : Structure and mechanism of Cu, Zn, superoxide dismutase. Nature 306, 274 (1983) |
27 | Charles, A. J. : Immunobiology, 5th, Life Science Publication Co, Seoul p. 350 (2002) |
28 | Beauchamp, C. and Fridovich, I. : Superoxide dismutase : improved assays and an assay applicable to acrylamide gel. Anal Biochem. 44, 276 (1971) |
29 | Kim, K. S., Shim, S. H., Jeong, K. H., Cheong, C. S., Ko, K. H., Park, J. I., Huh, H., Lee, B. J. and Kim, B. K. : Anti-diabetic activity of constituent of Lyii fructus. J. App. Pharmocol. 6, 378 (1998) |
30 | Lee, B. Y, Kim, E. J., Choi, H. D., Kim, Y. S., Kim, I. H. and Kim, S. S. : Physicochemical properties of Boxthorn (Lycii fructus) hot water extracts by roasting conditions. Korean J. Food Sci. Technol. 27, 768 (1995) |
31 | Dantzer, R., Bluthe, R. M., Gheusi, G., Cremona, S., Laye, S., Parnet, R and Kelley, K. W. : Molecular basis of sickness, behavior. Annals N. Y. Acad. Sci. 13, 856 (1998) |
32 | Halliwell, B.: How to charactrize a biological antioxidant. Free Radic. Res. Commun. 9, 598 (1990) |
33 | Kim, H. K., Na, G. M., Ye, S. H. and Han, H. S. : Extraction characteristics and antioxidative activity of Lycium chinense extracts. Korean J. Food Pre. 11, 352 (2004) |
34 | Choi, S. I., Lee, Y. M. and Heo, T. R. : Screening of hyaluronidase inhibitory and free radical scavenging activity in vitro of traditional herbal medicine extracts. Korean J. Biotechnol. Bioeng. 18, 282 (2003) |
35 | Jiangsu. : Chinese Medicine Dictionary. Shanghai Science and Technology Press Shanghai, China (1979) |
![]() |