1 |
Jaeschke, H. : Role of inflammation in the mechanism of acetaminophen-induced hepatotoxicity. Expert Opin. Drug Metab. Toxicol. 1, 389 (2005)
DOI
PUBMED
ScienceOn
|
2 |
Schwabe, R. F. and Brenner, D. A. : Mechanisms of liver injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways. Am. J. Physiol. Gastrointest. Liver Physiol. 290, G583 (2006)
DOI
ScienceOn
|
3 |
Tilg, H., Kaser, A. and Moschen, A. R. : How to modulate inflammatory cytokines in liver diseases. Liver Int. 26, 1029 (2006)
DOI
PUBMED
ScienceOn
|
4 |
Gu, M., Singh, R. P., Dhanalakshmi, S., Agarwal, C. and Agarwal, R. : Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice. Cancer Res. 67, 3483 (2007)
DOI
ScienceOn
|
5 |
Kang, J. S., Jeon, Y. J., Kim, H. M., Han, S. H. and Yang, K. H. : Inhibition of inducible nitric-oxide synthase expression by silymarin in lipopolysaccharide-stimulated macrophages. J. Pharmacol. Exp. Ther. 302, 138 (2002)
|
6 |
Polyak, S. J., Morishima, C., Shuhart, M. C., Wang, C. C., Liu, Y. and Lee, D. Y. : Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized silymarin. Gastroenterology 132, 1925 (2007)
DOI
PUBMED
ScienceOn
|
7 |
Beere, H. M. : Death versus survival: functional interaction between the apoptotic and stress-inducible heat shock protein pathways. J. Clin. Invest. 115, 2633 (2005)
DOI
ScienceOn
|
8 |
Das, S. K. and Vasudevan, D. M. : Protective effects of silymarin, a milk thistle (Silybium marianum) derivative on ethanol-induced oxidative stress in liver. Indian J. Biochem. Biophys. 43, 306 (2006)
PUBMED
|
9 |
Manna, S. K., Mukhopadhyay, A., Van, N. T. and Aggarwal, B. B. : Silymarin suppresses TNF-induced activation of NF-kappa B, c-Jun N-terminal kinase, and apoptosis. J. Immunol. 163, 6800 (1999)
|
10 |
Singh, R. P., Dhanalakshmi, S., Mohan, S., Agarwal, C. and Agarwal, R. : Silibinin inhibits UVB- and epidermal growth factor-induced mitogenic and cell survival signaling involving activator protein-1 and nuclear factor-kappaB in mouse epidermal JB6 cells. Mol. Cancer Ther. 5, 1145 (2006)
DOI
ScienceOn
|
11 |
Cho, J. Y., Skubitz, K. M., Katz, D. R. and Chain, B. M. : CD98-dependent homotypic aggregation is associated with translocation of protein kinase Cdelta and activation of mitogen-activated protein kinases. Exp. Cell Res. 286, 1 (2003)
DOI
PUBMED
ScienceOn
|
12 |
Kang, J. S., Park, S. K., Yang, K. H. and Kim, H. M. : Silymarin inhibits TNF-alpha-induced expression of adhesion molecules in human umbilical vein endothelial cells. FEBS Lett. 550, 89 (2003)
DOI
PUBMED
ScienceOn
|
13 |
Cho, J. Y., Baik, K. U., Jung, J. H. and Park, M. H. : In vitro anti-inflammatory effects of cynaropicrin, a sesquiterpene lactone, from Saussurea lappa. Eur. J. Pharmacol. 398, 399 (2000)
|
14 |
Kim, B. H. and Cho, J. Y. : Honokiol-mediated cytoprotective effects. J. Pharm. Pharmacol. Submitted (2007)
|
15 |
Roberts, R. A., Ganey, P. E., Ju, C., Kamendulis, L. M., Rusyn, I. and Klaunig, J. E. : Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis. Toxicol. Sci. 96, 2 (2007)
DOI
ScienceOn
|
16 |
Moulisova, V., Srbova, M., Jedlickova, O., Sebestian, J. and Jegorov, A. : Silybin reduces lipid peroxidation of rat hepatocyte membrane caused by cyclosporin A. Biochemistry (Mosc). 71, 1110 (2006)
DOI
ScienceOn
|
17 |
Li, Z. and Diehl, A. M. : Innate immunity in the liver. Curr. Opin. Gastroenterol. 19, 565 (2003)
DOI
ScienceOn
|
18 |
Yoo, H. G., Jung, S. N., Hwang, Y. S., Park, J. S., Kim, M. H., Jeong, M., Ahn, S. J., Ahn, B. W., Shin, B. A., Park, R. K. and Jung, Y. D. : Involvement of NF-kappaB and caspases in silibinin-induced apoptosis of endothelial cells. Int. J. Mol. Med. 13, 81 (2004)
PUBMED
|
19 |
Schumann, J., Prockl, J., Kiemer, A. K., Vollmar, A. M., Bang, R. and Tiegs, G. : Silibinin protects mice from T cell-dependent liver injury. J. Hepatol. 39, 333 (2003)
DOI
ScienceOn
|
20 |
Lee, J. S., Kim, S. G., Kim, H. K., Lee, T. H., Jeong, Y. I., Lee, C. M., Yoon, M. S., Na, Y. J., Sub, D. S., Park, N. C., Choi, I. H., Kim, G. Y., Choi, Y. H., Chung, H. Y. and Park, Y. M. : Silibinin polarizes Th1/Th2 immune responses through the inhibition of immunostimulatory function of dendritic cells. J. Cell Physiol. 210, 385 (2007)
DOI
ScienceOn
|
21 |
Varga, Z., Ujhelyi, L., Kiss, A., Balla, J., Czompa, A. and Antus, S. : Effect of silybin on phorbol myristate actetate-induced protein kinase C translocation, NADPH oxidase activity and apoptosis in human neutrophils. Phytomedicine. 11, 206 (2004)
DOI
ScienceOn
|
22 |
Gupta, O. P., Sing, S., Bani, S., Sharma, N., Malhotra, S., Gupta, B. D., Banerjee, S. K. and Handa, S. S. : Anti-inflammatory and anti-arthritic activities of silymarin acting through inhibition of 5-lipoxygenase. Phytomedicine. 7, 21 (2000)
|
23 |
Lee, S. K., Kim, H. S., Lee, H. J., Lee, J., Jeon, B. H., Jun, C. D., Lee, S. K. and Kim, E. C. : Dual effect of nitric oxide in immortalized and malignant human oral keratinocytes: induction of apoptosis and differentiation. J. Oral. Pathol. Med. 35, 352 (2006)
DOI
ScienceOn
|