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The Study of MLS-Resistant Gram Positive Cocci Isolated In a Korean Hospital  

Yoon, Eun-Jeong (College of Pharmacy and Reserach Institute of Pharmaceutical Sciences, Seoul National University)
Yoon, Jong-Min (College of Pharmacy and Reserach Institute of Pharmaceutical Sciences, Seoul National University)
Choi, Sung-Sook (Department of Pharmacy, Sahmyook University)
Kwon, Ae-Ran (College of Pharmacy and Reserach Institute of Pharmaceutical Sciences, Seoul National University)
Shim, Mi-Ja (Department of Life Science, University of Seoul)
Choi, Eung-Chil (College of Pharmacy and Reserach Institute of Pharmaceutical Sciences, Seoul National University)
Publication Information
YAKHAK HOEJI / v.50, no.3, 2006 , pp. 204-207 More about this Journal
Abstract
A total of 398 strains of Staphylococcus aureus (99), coagulase-negative staphylococci (CNS) (99), enterococci (100), Streptococcus pyogenes (18) and Streptococcus agalatiae (82) were in Korean tertiary hospital from Dec. 2004 to Mar, 2005. When minimal inhibitory concentrations (MIC), phenotypes and genotypes were determined, 70% of S. aureus, 65.7% of CNS, 78% of enterococci and 37.8% of S. agalatiae were resistant to erythromycin and 95.7% of erythromycin-resistant (EMR) S. aureus, 92.3% of EMR CNS and all of EMR enterococci and S. agalatiae had erm of the methylase gene or msr(A) of the efflux gene.
Keywords
macrolide resistance; Staphylococcus aureus; CNS; Streptococcus pyogenes; Streptococcus agalatiae; enterococci;
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