The Inhibitory Effect of CW-501027 and CW-501029 on the Anti-inflammatory Action in Rats |
Jung, Ji-Hoon
(Department of Pharmaccology, Chung Ang University)
Sim, Jae-Ho (Department of Pharmaccology, Chung Ang University) Yang, Sung-Jun (Department of Pharmaccology, Chung Ang University) Min, Young-Sil (Department of Pharmaccology, Chung Ang University) Song, Hyun-Ju (Department of Pharmaccology, Chung Ang University) Woo, Jae-Gwang (Department of Pharmaccology, Chung Ang University) Kim, Yong-Sung (Department of Pharmaccology, Chung Ang University) Cho, Young-Rae (Department of Pharmaccology, Chung Ang University) Sohn, Uy-Dong (Department of Pharmaccology, Chung Ang University) |
1 | Semble, E. L. and Wu, W. C. : NSAID-induced gastric mucosal damage. Am. Pam. Physician. 35(6), 101 (1987) |
2 | Wallace, J. L., Mccafferyty, D.-M., Carter, L., Mcknight, W. and Argentieri, D. : Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: anti-inflammatory without gastropathy? Gastroenerology 105, 1630 (1993) |
3 | Wallace, J. L., Reuter, B., Cicala, C., Mcknight, w., Grisham, M. B. and Cirino, G. : Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat. Gastroenerology 107, 173 (1994) DOI |
4 | Whittle, B. J. R., Higgs, G. A., Eakins, K. E., Moncada, S. and Vane,J. R. : Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa. Nature 284, 271 (1980) DOI ScienceOn |
5 | Granger, D. L., Hibbs, J. B., Pergect, Jr. J. R. and Durack, D. T. : Metabolic rate of L-arginine in relation to microbiostatic capability of murine macrophages. J. Clin. Invest. 88, 264(1990) |
6 | Wallace, J. L., Keenan, C. M. and Granger, D. N. : Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process. Am. J Physiol. 259, G462 (1990) |
7 | Wallace, J. L., Reuter, B., Cicala, C., Mcknight, W., Grisham, M. B. and Cirino, G. : A diclofenac derivative without ulcerogenic properties. Eur. J. Pharmacol. 257, 249 (1994) DOI ScienceOn |
8 | Pinon, J. F. : In vivo study of platelet aggregation in rats. J. Pharmacol. Methods 12, 79 (1984) |
9 | Vane, J. R. and Botting, R. M. : Mechanism of action of antiinflammatory drugs. Int. J. Tissue React. 20(1), 3 (1998) |
10 | Jun, C. D., Ryu, H., Um, J. Y., K, T. Y., Kim, J. M., Kang, S. S., Kim, H. M. and Chung, H. T. : Involvement of protein kinase C in the inhibition of nitric oxide production from murine microglial cell by glucocorticoid. Biochem. Biophys. Res. Commu. 199(2), 633 (1994) |