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Effects of Isatis indigitica on Anti-lipid Peroxidation and Low Density Lipoprotein Oxidation  

장현진 (숙명여자대학교 약학대학)
양기숙 (숙명여자대학교 약학대학)
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YAKHAK HOEJI / v.46, no.6, 2002 , pp. 448-451 More about this Journal
Abstract
Isatis indigotica is commonly used as traditional chinese medicine for antipyretic, antiviral, and detoxifying purpose in China. In order to examine whether it prevents lipid peroxidation, root of Isatis indigotica was extracted with methanol and fractionated with hexane, ethyl acetate, butanol and water. The activity was evaluated by DPPH method and lipid peroxidation in rat liver homogenate and C $u^{++}$ -induced oxidated LDL. The results showed that ethyl acetate fraction and indigo, which is known as its constituent, had significantly anti-lipid peroxidative effects.s.
Keywords
Isatis indigotica; lipid peroxidation; LDL oxidation;
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