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Distribution of Organochlorines and PCB Congeners in Korean Adipose Tissue, Liver and Whole Blood  

유영찬 (국립과학수사연구소)
이상기 (국립과학수사연구소)
김기욱 (국립과학수사연구소)
이수연 (국립과학수사연구소)
양자열 (국립과학수사연구소)
김윤신 (국립과학수사연구소 서부분소)
오승민 (성균관대학교 약학부)
정규혁 (성균관대학교 약학부)
Publication Information
YAKHAK HOEJI / v.46, no.4, 2002 , pp. 247-257 More about this Journal
Abstract
Persistent organochlorine pesticides and polychlorinated biphenyls (PCBs) have been used intensively in agriculture or industry for a long time. The occurrence of organochlorine pesticides and PCBs in the environment and subsequently in parts of the food chain, resulting in the intake of these compounds by man and animal. The measure of the levels of organochlorine pesticides and PCBs in tissues or blood of human populations are good markers in determining the extent of exposure and in the evaluating the hazards. So, most countriess have conducted initial monitoring programs to determine organochlorine pesticides and PCBs in human tissues. But a few report has been presented in Korea. In this study, $\alpha$-BHC, $\beta$-BHC, ${\gamma}$-BHC, $\delta$-BHC, p,p'-DDT, p,p'-DDD, p,p'-DDE, endrin, dieldein, aldrin and 7 marker PCBs (28, 52, 101, 118, 138, 153, 180) were determined in human blood, adipose tissue and liver tissues collected at autopsy of 10 men and 10 women, 13-79 year of age. Significant differences in the levels of organochlorine pesticides and PCBs between districts where they had lived were found in the following chemicals: total PCB in the blood : $\beta$-BHC, total BHC, p,p'-DDE and total DDT in the adipose tissue : p,p'-DDE, total DDT and PCB 118 in the liver. No significant difference was found in the levels of organochlorine pesticides and PCBs between sexes and ages. Though the levels of organochlorine pesticides and PCBs were relatively lower than that of other countries, we could know that organochlorine pesticides and PCBs have been widely distributed in Korean human body.
Keywords
PCB congeners; Organochlorines; Human tissues; Korean; GC/ECD;
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