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Clinical Study of Simultaneous Acquisition Rest 99mTc-sestaMIBI/Stress 201Tl Dual-Isotope Myocardial Perfusion Imaging with a Solid-State Dedicated Cardiac Gamma Camera  

Bahn, Young-Kag (Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System)
Kim, Dong-Heui (Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System)
Choi, Yong-Hoon (Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System)
Kang, Chun-Koo (Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System)
Kim, Jae-Sam (Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System)
Publication Information
The Korean Journal of Nuclear Medicine Technology / v.22, no.2, 2018 , pp. 88-91 More about this Journal
Abstract
Purpose The purpose of this study is to investigate the simultaneous dual isotope (SDI) myocardial perfusion scan that can be performed in a short time using a semiconductor gamma camera. Materials and Methods Of the 86 patients who underwent Rest/Stress $^{99m}TC$-sestaMIBI 1-day myocardial perfusion scan and Rest $^{99m}TC$-sestaMIBI/Stress $^{201}Tl$ simultaneous dual isotope myocardial perfusion scan using a heart-only gamma camera, the test results were the same, 36 patients who did not show any change in the clinical outcome. Quantitative values were statistically analyzed using a QPS program to confirm the correlation between the images of the two examinations. Results Rest/Stress $^{99m}TC$-sestaMIBI simultaneous dual myocardial perfusion scans and $^{99m}TC$-sestaMIBI/Stress $^{201}Tl$ double-isotope myocardial perfusion scans were analyzed for Summed score. The $R^2$ value of the Rest summed score (RSS) was 0.91 and the $R^2$ value of the stress summed score (SSS) was 0.71. Conclusion The $^{99m}TC$-sestaMIBI/Stress $^{201}Tl$ simultaneous dual isotope scan confirmed its correlation with the previous day's test. The $^{99m}TC$-sestaMIBI/Stress $^{201}Tl$ simultaneous dual isotope scan can be completed in approximately 30minutes. It maybe clinically useful for patients who need short examination time such as emergency patients or elderly patients.
Keywords
CZT Myocardial SPECT; Simultaneous Dual Isotope; SDI;
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1 Mouden M, Timmer JR, Ottervanger JP, et al. Impact of a new ultrafast CZT SPECT camera for myocardial perfusion imaging: fewer equivocal results and lower radiation dose. Eur J Nucl Med Mol Imaging. 2012;39:1048-1055.   DOI
2 Duvall WL, Croft LB, Ginsberg ES, et al. Reduced isotope dose and imaging time with a high-efficiency CZT SPECT camera. J Nucl Cardiol. 2011;18:847-857.   DOI
3 Songy B, Guernou M, Lussato D, et al. Low-dose thallium-201 protocol with a cadmium-zinc-telluride cardiac camera. Nucl Med Commun. 2012;33:464-469.   DOI
4 Rajaram R, Bhattacharya M, Ding X, et al. Tomographic performance characteristics of the IQSPECT system. IEEE Nucl Sci Symp Conf Rec. 2011; 2451-2456.
5 Erlandsson K, Kacperski K, Van Gramberg D, Hutton BF. Performance evaluation of D-SPECT: a novel SPECT system for nuclear cardiology. Phys Med Biol. 2009;54:2635-2649.   DOI
6 Bocher M, Blevis IM, Tsukerman L, Shrem Y, Kovalski G, Volokh L. A fast cardiac gamma camera with dynamic SPECT capabilities: design, system validation and future potential. Eur J Nucl Med Mol Imaging. 2010;37: 1887-1902.   DOI
7 Laetitia I, Sylvain P, Philippe R. F, et al. Compared Performance of High-Sensitivity Cameras Dedicated to Myocardial Perfusion SPECT: A Comprehensive Analysis of Phantom and Human Images. J Nucl Med 2012; 53:1897-1903   DOI
8 Pazhenkottil AP, Buechel RR, Herzog BA, et al. Ultrafast assessment of left ventricular dyssynchrony from nuclear myocardial perfusion imaging on a new high-speed gamma camera. Eur J Nucl Med Mol Imaging. 2010;37:2086-2092.   DOI
9 Schillaci O, Danieli R. Dedicated cardiac cameras: a new option for nuclear myocardial perfusion imaging. Eur J Nucl Med Mol Imaging. 2010;37:1706-1709.   DOI
10 Buechel RR, Pazhenkottil AP, Herzog BA, et al. Real-time breath-hold triggering of myocardial perfusion imaging with a novel cadmium-zinctelluride detector gamma camera. Eur J Nucl Med Mol Imaging. 2010;37: 1903-1908.   DOI
11 Simona B, Krzysztof K, Sharon H, et al. Simultaneous dual-radionuclide myocardial perfusion imaging with a solid-state dedicated cardiac camera. Eur J Nucl Med Mol Imaging. Published online: 11 April 2010.
12 Ayano Makita, Naoya Matsumoto, Yasuyuki Suzuki, et. al. Clinical Feasibility of Simultaneous Acquisition Rest $^{99m}Tc$/Stress 201Tl Dual-Isotope Myocardial Perfusion Single-Photon Emission Computed Tomography With Semiconductor Camera. Circulation Journal. Published online: 18 January 2016.