Browse > Article
http://dx.doi.org/10.3831/KPI.2020.23.4.187

Different Point of View to the Autoimmune Diseases and Treatment with Acupuncture  

Inanc, Betul Battaloglu (Family Medicine Department, Faculty of Medicine, Mugla Sitki Kocman University)
Publication Information
Journal of Pharmacopuncture / v.23, no.4, 2020 , pp. 187-193 More about this Journal
Abstract
Objectives: It was aimed to investigate the basic action mechanism of the autoimmune diseases and common features of all diseases. Autoimmune disease are classified organ specific and systemic. Methods: These diseases are seen systemic and disease start locations, origins seem differently. This makes learning and understanding difficult. Autoimmune diseases investigated for easier understanding. It was noticed that, autoimmune diseases' starting places are specific and same all of them. This remarkable point is very important for acupuncture also. So; whole literatüre was researched and important point was found. Results: Whole autoimmune diseases are attack to mesodermal layers and mesodermal origin organs of the body's. The common property of all these disease are same; Diseases start from the mesoderm and mesodermal layer even though their organ origins' belongs to different germ layer. From this point of view, we were able to classify autoimmune diseases simply and it was planned how can we effect body in this context with acupuncture. Conclusion: And, when immunity comes into question, induction of adaptive immunity is depend on antigen presentation to T cells and this situation take place in the lymph node (LN) and also in the skin.When we sank the acupuncture needle into skin, signals create and start mesodermal contacts, during this time mesenchymal origin' autoimmune cells are regulated with this signals.
Keywords
autoimmunity; mesoderm; ectoderm; skin; acupuncture; inflamation; immunmodulation;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Torres-Rosas R, Yehia G, Pena G, Mishra P, del Rocio Thompson-Bonilla M, Moreno-Eutimio MA, et al. Dopamine mediates vagal modulation of the immune system by electroacupuncture. Nat Med. 2014;20(3):291-5.   DOI
2 Silverio-Lopes S, da Mota MPG. Acupuncture in modulation of immunity. In: Chen LL, Cheng TO, editors. Acupuncture in modern medicine. London: InTech; 2013. p. 51-76.
3 Cabioglu MT, Cetin BE. Acupuncture and immunomodulation. Am J Chin Med. 2008;36(1):25-36.   DOI
4 Chen Y, Lyga J. Brain-skin connection: stress, inflammation and skin aging. Inflamm Allergy Drug Targets. 2014;13(3):177-90.   DOI
5 Slominski A, Wortsman J. Neuroendocrinology of the skin. Endocr Rev. 2000;21(5):457-87.   DOI
6 Egawa G, Kabashima K. Skin as a peripheral lymphoid organ: revisiting the concept of skin-associated lymphoid tissues. J Invest Dermatol. 2011;131(11):2178-85.   DOI
7 Takahashi T, Sumino H, Kanda T, Yamaguchi N. Acupuncture modifies immune cells. J Exp Clin Med. 2009;1(1):17-22.   DOI
8 Simmonds MJ, Gough SCL. Genetic insights into disease mechanisms of autoimmunity. Br Med Bull. 2005;71(1):93-113.   DOI
9 Frohlich E, Wahl R. Thyroid autoimmunity: role of anti-thyroid antibodies in thyroid and extra-thyroidal diseases. Front Immunol. 2017;8:521.   DOI
10 Vyse TJ, Todd JA. Genetic analysis of autoimmune disease. Cell. 1996;85(3):311-8.   DOI
11 Wu H, Chen H, Hua X, Shi Z, Zhang L, Chen J. Clinical therapeutic effect of drug-separated moxibustion on chronic diarrhea and its immunologic mechanisms. J Tradit Chin Med. 1997;17(4):253-8.
12 Sadler TW, Langman J. Langman's medical embryology. 12th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkin; 2012. p. 50-110.
13 Adams DD, Purves HD. Abnormal response in the assay of thyrotropin. Proc Univ Otago Med Sch. 1956;34:11-2.
14 Chlumska A, Boudova L, Benes Z, Zamecnik M. Autoimmune gastritis. A clinicopathologic study of 25 cases. Cesk Patol. 2005; 41(4):137-42.
15 Bail K, Notz Q, Rovituso DM, Schampel A, Wunsch M, Koeniger T, et al. Differential effects of FTY720 on the B cell compartment in a mouse model of multiple sclerosis. J Neuroinflammation. 2017;14(1):148.   DOI
16 Minalyan A, Benhammou JN, Artashesyan A, Lewis MS, Pisegna JR. Autoimmune atrophic gastritis: current perspectives. Clin Exp Gastroenterol. 2017;10:19-27.   DOI
17 Derkus B, Acar Bozkurt P, Tulu M, Emregul KC, Yucesan C, Emregul E. Simultaneous quantification of Myelin Basic Protein and Tau proteins in cerebrospinal fluid and serum of Multiple Sclerosis patients using nanoimmunosensor. Biosens Bioelectron. 2017;89(Pt 2):781-8.   DOI
18 Becker KG. Comparative genetics of type 1 diabetes and autoimmune disease: common loci, common pathways? Diabetes. 1999;48(7):1353-8.   DOI
19 Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology. 2004;126(6):1504-17.   DOI
20 Bryant RV, Winer S, Travis SP, Riddell RH. Systematic review: histological remission in inflammatory bowel disease. Is 'complete' remission the new treatment paradigm? An IOIBD initiative. J Crohns Colitis. 2014;8(12):1582-97.   DOI
21 Moustakas A, Pardali K, Gaal A, Heldin CH. Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation. Immunol Lett. 2002;82(1-2):85-91.   DOI
22 Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature. 1998;392(6673):245-52.   DOI
23 Kim SK, Bae H. Acupuncture and immune modulation. Auton Neurosci. 2010;157(1-2):38-41.   DOI