Browse > Article
http://dx.doi.org/10.3831/KPI.2020.23.3.91

Ethnomedicinal Uses, Phytochemistry and Pharmacology of Dorema Species (Apiaceae): A Review  

Zibaee, Elaheh (Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences)
Amiri, Mohammad Sadegh (Department of Biology, Payame Noor University)
Boghrati, Zahra (Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences)
Farhadi, Faeghe (Department of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences)
Ramezani, Mahin (Nanotechnology Research Center, Mashhad University of Medical Sciences)
Emami, Seyed Ahmad (Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences)
Sahebkar, Amirhossein (Halal Research Center of IRI, FDA)
Publication Information
Journal of Pharmacopuncture / v.23, no.3, 2020 , pp. 91-123 More about this Journal
Abstract
The application of antique medical instructions, practices, skills and knowledge has been considered as the most affordable treatment in many developing countries. The use of these preparations and prescriptions over generations has made a useful and valuable guide for drug discovery in modern medicine. Medical herbs have been of a high importance for this purpose. The genus Dorema, of Apiaceae family (Umbelliferae) has a wide use in ethnobotany and traditional medicine around the world. It has been used as a treatment for CNS disease, convulsion, upper respiratory tract problems, gastrointestinal disorder and high blood sugar. Furthermore, phytochemical investigations have reported Dorema species to contain a wide range of constituents including terpenes, coumarins and phenolic compounds. The current review summarizes comprehensive information regarding botany, phytochemistry and pharmacological aspects of Dorema spp.
Keywords
Dorema; phytochemistry; pharmacology;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Hosseini SAR, Naseri HR, Azarnivand H, Jafari M, Rowshan V, Panahian AR. Comparing stem and seed essential oil in Dorema ammoniacum D. Don. from Iran. J Essent Oil Bear Plants. 2014;17(6):1287-92.   DOI
2 Zandpour F, Vahabi MR, Allafchian AR, Farhang HR. Phytochemical investigation of the essential oils from the leaf and stem of (Apiaceae) in Central Zagros, Iran. J Herb Drugs. 2016;7(2):109-16.
3 Masoudi S, Kakavand S. Volatile constituents of the aerial parts of Terataenium lasiopentalum (Boiss.) Manden., stems and leaves of Dorema ammoniacum D. Don. and leaves, fruits and stems of Leutea petiolare (DC.) M. Pimen from Iran. J Chil Chem Soc. 2017;62(1):3311-4.   DOI
4 Tahvilian R, Shahriari S, Faramarzi A, Komasi A. Ethnopharmaceutical formulations in kurdish ethno-medicine. Iran J Pharm Res. 2014;13(3):1029-39.
5 Khatamsaz S, Azarnioshan F, Sadeghi H. Effects of hydroalcoholic extract of Dorema aucheri on pituitary-gonad axis hormones in adult male rats. Nat Environ Pollut Technol. 2010;9(3):507-11.
6 Ahangarpour A, Zamaneh HT, Jabari A, Nia HM, Heidari H. Antidiabetic and hypolipidemic effects of Dorema aucheri hydroalcoholic leave extract in streptozotocin-nicotinamide induced type 2 diabetes in male rats. Iran J Basic Med Sci. 2014;17(10):808-14.
7 Mostafavi SH, Fazilati M, Mostafavi SA, Vahhabi MR, Mostafavi F, Omidvarinia S, et al. Hepatotoxicity of Dorema aucheri (Bilhar) in albino mice. Arch Iran Med. 2013;16(9):530-2.
8 Motevalian M, Mehrzadi S, Ahadi S, Shojaii A. Anticonvulsant activity of Dorema ammoniacum gum: evidence for the involvement of benzodiazepines and opioid receptors. Res Pharm Sci. 2017;12(1):53-9.   DOI
9 Akbarian A, Rahimmalek M, Sabzalian MR. Variation in essential oil yield and composition of Dorema aucheri Boiss., an endemic medicinal plant collected from wild populations in natural habitats. Chem Biodivers. 2016;13(12):1756-66.   DOI
10 Masoudi S, Esmaeili A, Ali khalilzadeh M, Rustaiyan A, Moazami N, Akhgar MR, et al. Volatile constituents of Dorema aucheri Boiss., Seseli libanotis (L.) W. D. Koch var. armeniacum Bordz. and Conium maculatum L. three Umbelliferae herbs growing wild in Iran. Flavour Fragr J. 2006;21(5):801-4.   DOI
11 Delnavazi MR, Hadjiakhoondi A, Delazar A, Ajani Y, Tavakoli S, Yassa N. Phytochemical and antioxidant investigation of the aerial parts of Dorema glabrum Fisch. & C.A. Mey. Iran J Pharm Res. 2015;14(3):925-31.
12 Yousefzadi M, Mirjalili HM, Alnajar N, Zeinali A, Parsa M. Composition and in vitro antimicrobial activity of the essential oil of Dorema ammoniacum D. Don. fruit from Iran. J Serbian Chem Soc. 2011;76(6):857-63.   DOI
13 Asnaashari S, Dadizadeh E, Talebpour AH, Eskandani M, Nazemiyeh H. Free radical scavenging potential and essential oil composition of the Dorema glabrum Fisch. C.A. Mey roots from Iran. Bioimpacts. 2011;1(4):241-4.
14 Bibi T, Ahmad M, Ahmadbaloch I, Muhammad S, Manzoor R. Ethnomedicinal uses of plants for child birth and postpartum recovery in District Pishin, Northern Balochistan, Pakistan. Int J Biol Pharm Allied Sci. 2017;6(9):1730-60.
15 Mir-Babayev NF, Gasanov GG, Knight DW. Plants of the Republic of Azerbaijan with potential medicinal applications. Int J Pharmacogn. 1993;31(1):47-54.   DOI
16 Gintzburger G. Rangelands of the arid and semi-arid zones in Uzbekistan. Montpellier: CIRAD; 2003. p. 91.
17 Emami SA, Nadjafi F, Amine GH, Amiri MS, Khosravi MT, Nasseri M. [Les especes de plantes medicinales utilisees par les guerisseurs traditionnels dans la province de Khorasan, nord-est de l'Iran]. Ethnopharmacologia. 2012;48:48-59. French.
18 Koohpayeh A, Ghasemi Pirbalouti A, Yazdanpanah Ravari MM, Pourmohseni Nasab E, Arjomand D. Study the ethno-veterinary of medicinal plants in Kerman province, Iran. J Herb Drugs. 2011;2(3):211-6.
19 Sadeghi Z, Mahmood A. Ethno-gynecological knowledge of medicinal plants used by Baluch tribes, southeast of Baluchistan, Iran. Rev Bras Farmacogn. 2014;24(6):706-15.   DOI
20 Ibn Sina H. [Al-Qanun fi'l-Tibb (Canon of medicine)]. New Delhi: Jamia Hamdard; 1998. p. 30. Arabic.
21 Ibn al-Baytar AA. [Al-Jamee le-Mofradaat al-Adwiah wa al-Aghziyah (Book in simple drugs and foods)]. Beirut: Dar al-Kotob al-Ilamiyah; 1992. p. 47-48. Arabic.
22 Ali GB, Mahdi F. The possibility of crop cultivation and utilization of edible gum from herb (Dorema ammoniacum D. Don) in dryland farming. J Agric Sci. 2015;60(3):369-80.
23 Mozaffarian V. [Flora of Iran]. Tehran: Research Institute of Forests and Rangelands; 2007. Chapter 54, Umbelliferae; p. 368-74. Persian.
24 Rabe SZT, Iranshahi M, Rastin M, Rabe SZT, Mahmoudi M. Anti-inflammatory effect of new kopetdaghins A, C and E from Dorema kopetdaghense. Food Agric Immunol. 2015;26(3):430-9.   DOI
25 Amin GR. Popular medicinal plants of Iran. 1. Tehran: Iranian Research Institute of Medicinal Plants; 1991. 230 p.
26 Langenheim JH. Plant resins: chemistry, evolution, ecology and ethnobotany. Portland: Timber Press; 2003. p. 123-9.
27 Ghasani AM. [Hadiqat al-Azhar fi Mahiyyat al-ushb wa aluqqar]. Beirut: Dar al-Gharb al-Islami; 1990. p. 38. Arabic.
28 Nahvinejad M, Pourrajab F, Hekmatimoghaddam S. Extract of Dorema aucheri induces PPAR-${\gamma}$ for activating reactive oxygen species metabolism. J Herb Med. 2016;6(4):171-9.   DOI
29 Behpour M, Ghoreishi SM, Khayatkashani M, Soltani N. The effect of two oleo-gum resin exudate from Ferula assa-foetida and Dorema ammoniacum on mild steel corrosion in acidic media. Corros Sci. 2011;53(8):2489-501.   DOI
30 Husseini Tonekaboni MM. [Tohfah al-Momenin (Rarity of the faithful)]. Tehran: Shahr Publishers; 2008. p. 47. Persian.
31 Aqili Khorasani MH. [Makhzan al-Adwiah (Drug treasure)]. Tehran: Sabz Arang Publisher; 2014. p. 170-1. Persian.
32 Ajani Y, Ajani A, Cordes JM, Watson MF, Downie SR. Phylogenetic analysis of nrDNA ITS sequences reveals relationships within five groups of Iranian Apiaceae subfamily Apioideae. Taxon. 2008;57(2):383-401.
33 Amiri MS, Joharchi MR. Ethnobotanical investigation of traditional medicinal plants commercialized in the markets of Mashhad, Iran. Avicenna J Phytomed. 2013;3(3):254-71.
34 Schischkin BK. [Flora SSSR. 17]. Leningrad: Izd-vo Akademii Nauk SSSR; 1951. p. 155-65. Russian.
35 Pimenov MG, Leonov MV, Constance L. The genera of the Umbelliferae: a nomenclator. London: Royal Botanic Gardens; 1993. 156 p.
36 Rechinger KH. Umbelliferae. Graz: Akademische; 1987. p. 379-85.
37 Amiri MS, Joharchi MR. Ethnobotanical knowledge of Apiaceae family in Iran: a review. Avicenna J Phytomed. 2016;6(6):621-35.
38 Nurmukhamedova MR, Nikonov GK. Glycosides of Dorema hyrcanum. Chem Nat Compd. 1976;12(1):92-3.   DOI
39 Iranshahi M, Shaki F, Mashlab A, Porzel A, Wessjohann LA. Kopetdaghins A-E, sesquiterpene derivatives from the aerial parts and the roots of Dorema kopetdaghense. J Nat Prod. 2007;70(8):1240-3.   DOI
40 Eskandani M, Dadizadeh E, Hamishehkar H, Nazemiyeh H, Barar J. Geno/cytotoxicty and apoptotic properties of phenolic compounds from the seeds of Dorema glabrum fisch. C.A. Bioimpacts. 2014;4(4):191-8.   DOI
41 Bukreeva TV, Pimenov MG. 2,6-Dihydroxy-4-methoxyacetophenone 2-O-${\beta}$-D-gentiobioside from the roots of Dorema aitchisonii. Chem Nat Compd. 1991;27(5):638-9.   DOI
42 Delnavazi MR, Hadjiakhoondi A, Delazar A, Ajani Y, Yassa N. Azerosides A and B: two new phloroacetophenone glycosides from the roots of Dorema glabrum Fisch. & C.A. Mey. Med Chem Res. 2015;24(2):787-96.   DOI
43 Nykolov N, Iossifova T, Vassileva E, Kostova I, Stoev G. Reverse-phase high pressure liquid chromatographic analysis of hydroxycoumarins in plant extracts. Quantitative determination of hydroxycoumarins in Fraxinus ornus. Phytochem Anal. 1993;4(2):86-8.   DOI
44 Morikawa T, Imura K, Miyake S, Ninomiya K, Matsuda H, Yamashita C, et al. Promoting the effect of chemical constituents from the flowers of Poacynum hendersonii on adipogenesis in 3T3-L1 cells. J Nat Med. 2012;66(1):39-48.   DOI
45 Jorjani SE. [Zakhire Kharazmshahi (Treasure of Kharazmshah), photo print of the manuscript dated 1206]. Tehran: AD Sirjani; 1976. p. 191. Persian.
46 Ibn Nafis Qarshi AD. [Al-Mujaz fi'l-Tibb (A Commentary on Ibn Sina's Canon)]. Cairo: Ihyaa al-Torath al-Islami; 2001. p. 83. Arabic.
47 Jorjani SEI. [Al-Aghraz al-Tibbia val Mabahess al-Alaiia (Medical goals and Allaii's discussions)]. Tehran: University of Tehran Press; 2006. p. 284. Persian.
48 Antaki D. [Tazkere oulol-albab (Memorandum book)]. Beirut: Dar-al-Kotob al-ilmiyah; 2000. p. 51. Arabic.
49 Rajani M, Saxena, N, Ravishankara MN, Desai N, Padh H. Evaluation of the antimicrobial activity of ammoniacum gum from Dorema ammoniacum. Pharm Biol. 2002;40(7):534-41.   DOI
50 Kumar VP, Chauhan NS, Padh H, Rajani M. Search for antibacterial and antifungal agents from selected Indian medicinal plants. J Ethnopharmacol. 2006;107(2):182-8.   DOI
51 Abedini A, Roumy V, Mahieux S, Gohari A, Farimani MM, Riviere C, et al. Antimicrobial activity of selected Iranian medicinal plants against a broad spectrum of pathogenic and drug multiresistant micro-organisms. Lett Appl Microbiol. 2014;59(4):412-21.   DOI
52 Delnavazi MR, Tavakoli S, Rustaie A, Batooli H, Yassa N. Antioxidant and antibacterial activities of the essential oils and extracts of Dorema ammoniacum roots and aerial parts. Res J Pharmacogn. 2014;1(4):11-8.
53 Mosaddegh M, Naghibi F, Moazzeni H, Pirani A, Esmaeili S. Ethnobotanical survey of herbal remedies traditionally used in Kohghiluyeh va Boyer Ahmad province of Iran. J Ethnopharmacol. 2012;141(1):80-95.   DOI
54 Memariani F, Akhani H, Joharchi MR. Endemic plants of Khorassan-Kopet Dagh floristic province in Irano-Turanian region: diversity, distribution patterns and conservation status. Phytotaxa. 2016;249(1):31-117.   DOI
55 Sadeghei Takallo M, Sajjadifar S, Avval MM. Chemical composition of the essential oils from flowers, stems and roots of Dorema ammoniacum D.Don from Iran. Res J Pharm Biol Chem Sci. 2013;4(4):640-4.
56 Kraus C, Spiteller G. Comparison of phenolic compounds from galls and shoots of Picea glauca. Phytochemistry. 1997;44(1):59-67.   DOI
57 Mianabadi M, Hoshani M, Salmanian S. Antimicrobial and antioxidative effects of methanolic extract of Dorema aucheri Boiss. J Agric Sci Technol. 2015;17(3):623-34.
58 Yazdi FT, Behbahani BA, Vasiee A, Mortazavi SA, Yazdi FT. An investigation on the effect of alcoholic and aqueous extracts of Dorema aucheri (Bilhar) on some pathogenic bacteria in vitro. J Paramed Sci. 2015;6(1)58-64.
59 Mirzaei A, Mirzaei N, Ghavamizadeh M. Antioxidant activity and cytotoxicity of Dorema aucheri by Artemia urmiana : a brine shrimp lethality test. Life Sci J. 2013;10:8-12.
60 Naghibi F, Ghafari S, Esmaeili S, Jenett-Siems K. Naghibione; a novel sesquiterpenoid with antiplasmodial effect from Dorema hyrcanum Koso-Pol. Root, a plant used in traditional medicine. Iran J Pharm Res. 2015;14(3):961-8.
61 Lev E, Amar Z. Ethnopharmacological survey of traditional drugs sold in the Kingdom of Jordan. J Ethnopharmacol. 2002;82(2-3):131-45.   DOI
62 Mohamadi N, Sharififar F, Koohpayeh A, Daneshpajouh M. Traditional and ethnobotanical uses of medicinal plants by ancient populations in Khabr and Rouchon of Iran. J Appl Pharm Sci. 2015;5(11):101-7.
63 Rajaei P, Mohamadi N. Ethnobotanical study of medicinal plants of hezar mountain allocated in South East of Iran. Iran J Pharm Res. 2012;11(4):1153-67.
64 Zarshenas MM, Arabzadeh A, Ajdari Tafti M, Kordafshari G, Zargaran A, Mohagheghzadeh A. Application of herbal exudates in traditional Persian medicine. Galen Med J. 2013;1(2):78-83.
65 Khare CP. Indian medicinal plants: an illustrated dictionary. Berlin: Springer; 2007. 812 p.
66 Chevallier A. The encyclopedia of medicinal plants. London: DK; 1996. 336 p.
67 Amini MH, Hamdam SH. Medicinal plants used traditionally in Guldara district of Kabul, Afghanistan. Int J Pharmacogn Chinese Med. 2017;1(3):1-13.
68 Baloch AH, Baloch IA, Haneef-ur-Rehman SRS, Jaffar A. Contribution to the knowledge of ethnobotany of Balochistan, Pakistan. Lasbela Univ J Sci Technol. 2016;1:143-73.
69 Khan A, Farooq U, Ullah F, Iqbal J, Khan AF, Zaib S, et al. Determination of biological activities and total phenolic contents of flowers of Jasminum humile and roots of Dorema aucheri . J Chem Soc Pak. 2014;36(2):291-5.
70 Habibi H, Firouzi S, Nili H, Razavi M, Asadi SL, Daneshi S. Anticoccidial effects of herbal extracts on Eimeria tenella infection in broiler chickens: in vitro and in vivo study. J Parasit Dis. 2016;40(2):401-7.   DOI
71 Etebari M, Sajjadi SE, Jafarian-Dehkordi A, Nazmakanipour S. Genotoxicity evaluation of hydroalcoholic and aqueous extracts of Dorema aucheri by the comet assay. Adv Biomed Res. 2016;5:199.   DOI
72 Jafari N, Zargar SJ, Yassa N, Delnavazi MR. Induction of apoptosis and cell cycle arrest by Dorema glabrum root extracts in a gastric adenocarcinoma (AGS) cell line. Asian Pac J Cancer Prev. 2016;17(12):5189-93.   DOI
73 Bannazadeh Amirkhiz M, Rashtchizadeh N, Nazemiyeh H, Abdolalizadeh J, Mohammadnejad L, Baradaran B. Investigating apoptotic effects of methanolic extract of Dorema glabrum seed on WEHI-164 cells. ISRN Pharmacol. 2013;2013:949871.   DOI
74 Bannazadeh Amirkhiz M, Rashtchizadeh N, Nazemieh H, Abdolalizadeh J, Mohammadnejad L, Baradaran B. Cytotoxic effects of alcoholic extract of Dorema glabrum seed on cancerous cells viability. Adv Pharm Bull. 2013;3(2):403-8.
75 Shahidi GH, Moein MR, Foroumadi AR, Rokhbakhsh ZF. Cytotoxic activity of medicinal plants used in Iranian traditional medicine on two strains of Saccharomyces cerevisiae . Daru J Pharm Sci. 2002;10(4):162-4.
76 Mosaddegh M, Esmaeili S, Naghibi F, Moghadam MH, Haeri A, Pirani A, et al. Ethnomedical survey and cytotoxic activity of medicinal plant extracts used in Kohgiluyeh and Boyerahmad province in Iran. J Herbs Spices Med Plants. 2012;18(3):211-21.   DOI