A Study on the Oral Toxicity of Mecasin in Rats |
Jeong, Hohyun
(Department of Acupuncture & Moxibustion Medicine, Wonkwang University Gwangju Korean Medical Hospital)
Lee, Jongchul (Department of Acupuncture & Moxibustion Medicine, Wonkwang University Gwangju Korean Medical Hospital) Cha, Eunhye (Department of Acupuncture & Moxibustion Medicine, Wonkwang University Gwangju Korean Medical Hospital) Park, Manyong (Department of Acupuncture & Moxibustion Medicine, Wonkwang University Gwangju Korean Medical Hospital) Son, Ilhong (Department of Neurology, Inam Neuroscience Research Center, Sanbon Medical Center, College of Medicine, Wonkwang University) Song, Bongkeun (Department of Internal Medicine, Wonkwang University Gwangju Korean Medical Hospital) Kim, Sungchul (Department of Acupuncture & Moxibustion Medicine, Wonkwang University Gwangju Korean Medical Hospital) |
1 | Guo L, Cho SY, Kang SS, Lee SH, Baek HY, Kim YS. Orthogonal array design for optimizing extraction efficiency of active constituents from jakyak-gamcho decoction, the complex formula of herbal medicines, paeoniae radix and glycyrrhizae radix. J Ethnopharmacol. 2007;113(2):306-11. DOI ScienceOn |
2 | Kang TH, Baek HY, Kim YC. Protective effect of jakyak-gamcho-tang extract and its constituents against t-BHP-induced oxidative damage in HT22 cells. Am J Chin Med. 2005;33(2):181-9. DOI ScienceOn |
3 | Lee JM, Hong SY, Oh MS. Effects of jakyakkamchobuja-tang on papain-induced osteoarthritis in mice. J Korean Oriental Med. 2013;34(1):116-35. |
4 | Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. Mayo Clin Proc. 2003;78(6):767-8. DOI ScienceOn |
5 | Kim JK, Kim SH, Lee SM, Jeong HY, Park MY, Kim DW, et al. Study of single-dose toxicity of aconitum kusnezoffii reichb. pharmacopuncture in rats. J Pharmacopunct. 2012;15(3):48-52. 과학기술학회마을 DOI ScienceOn |
6 | Sun JK, Shin MK. Cytotoxic effect of salvia miltiorrhiza root against L1210 cell. J Orient Neuropsychiatry. 1992;3(1):84-90. |
7 | Roh HS, Jeong JY, Seok Jh, Ha HY. Acute oral toxicity of root of polygala teunifolia wild. extract. J Orient Obstet Gynecol. 2013;26(4):1-13. |
8 | Kim YH, Seo BI. A philological study on poisoning and side effects of gastrodiae rhizoma. The Journal of Jeahan Oriental Medical Academy. 2012;10(1):137-45. |
9 | Choi EY, Oh HJ, Park NK, Chun HJ, Ahn JW, Jeon BH, et al. [Screening of cytotoxicity and antimicrobial effects of extracts from the atractylodes macrocephala koidz]. J Orient Physiol Pathol. 2002;16(2):348-52. Korean. 과학기술학회마을 |
10 | Fang YS, Shan DM, Liu JW, Xu W, Li CL, Wu HZ, et al. Effect of constituents from fructus aurantii immaturus and radix paeoniae alba on gastrointestinal movement. Planta Med. 2009;75(1):24-31. DOI ScienceOn |
11 | Huang KS, Lin JG, Lee HC, Tsai FJ, Bau DT, Huang CY, et al. Paeoniae alba radix promotes peripheral nerve regeneration. Evid Based Complement Alternat Med. 2011;109809:1-8. |
12 | Park HJ, Shim HS, Kim H, Kim KS, Lee H, Hahm DH, et al. Effects of glycyrrhizae radix on repeated restraint stress-induced neurochemical and behavioral responses. Korean J Physiol Pharmacol. 2010;14(6):371-6. 과학기술학회마을 DOI ScienceOn |
13 | Tong P, Wu C, Wang X, Hu H, Jin H, Li C, et al. Development and assessment of a complete-detoxi arthritis cation strategy for fuzi (lateral root of aconitum carmichaeli) and its application in rheumatoid therapy. J Ethnopharmacol. 2013;146(2):562-71. DOI ScienceOn |
14 | J. Singhuber, M. Zhu, S. Prinz, B. Kopp. Aconitum in traditional chinese medicine: a valuable drug or an unpredictable risk?. J Ethnopharmacol. 2009;126(1):18-30. DOI ScienceOn |
15 | Miao Q. New advance in identification of chinese medicine tianma. China Medical Herald. 2011;8(20):20-5. |
16 | Kim DR, Kim HY, Park JK, Park SK, Chang MS. Aconiti lateralis preparata radix activates the proliferation of mouse bone marrow mesenchymal stem cells and induces osteogenic lineage differentiation through the bone morphogenetic protein-2/smad-dependent run2 pathway. Evid Based Complement Alternat Med. 2013;586741:1-11. |
17 | Hu F, Koon CM, Chan JY, Lau KM, Fung KP. The cardioprotective effect of danshen and gegen decoction on rat hearts and cardiomyocytes with post-ischemia reperfusion injury. BMC Complement Altern Med. 2012;12:249. DOI |
18 | Lee HG, Kim YS. Effects of salvia miltriorrhiza radix on neuronal apoptosis following intracerebral hemorrhage of rats. Kor J Herbology. 2012;27(3):89-94. 과학기술학회마을 DOI ScienceOn |
19 | Tang XH, Li B, Hu LY, Hu Zuo, YE Q, ZHU H, et al. [The compatibility applications of tianma]. Journal of Shanxi College of Traditional Chinese Medicine. 2012;13(3):75-6. Chinese. |
20 | Shin IJ, Son SU, Park H, Kim Y, Park SH, Swanberg K, et al. Preclinical evidence of rapid-onset antidepressant-like effect in radix polygalae extract. Plos One. 2014;9(2):e88617. DOI |
21 | Qin L, Yang YB, Tuo QH, Zhu BY, Chen LX, Zhang L, et al. Effects and underlying mechanisms of curcumin on the proliferation of vascular smooth muscle cells induced by chol:MbetaCD. Biochem Biophys Res Commun. 2009;379(2):277-82. DOI ScienceOn |
22 | Ryu HW, Kim YS, Lim EM. The Anti inflammatory Effects of Chaenomelis Fructus Herba Water Extract on Mouse RAW 264.7 Cell. J Orient Obstet Gynecol. 2012; 25(3): 1-15. |
23 | Korea Food & Drug Administration notification. Seoul: Korea Food & Drug Administration; 2005. p. 60. |
24 | Shin DS, Kim YI, Lee H. [Effect of herbal-acupuncture with chaenomelis fructus solution at the joksamni of mice with collagen-induced arthritis]. The Acupuncture. 2007;24(3):127-43. Korean. |
25 | Kim YK. [The principle and test method. toxicology]. Seoul: Donghwagisul; 1994(3). p. 15-8. Korean. |
26 | Kim YG. [Toxicology]. Seoul: Donghwagisul; 1984. p. 15-8. Korean. |