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http://dx.doi.org/10.3831/KPI.2013.16.008

Review of Cervi Cornu Parvum Pharmacopuncture in Korean Medicine  

Lee, Dong-Jin (Department of Ophthalmology, Otolaryngology and Dermatology, Pusan National University Korean Medicine Hospital)
Hwangbo, Min (Department of Ophthalmology, Otolaryngology and Dermatology, Daegu Korean Medicine Hospital of Daegu Hanny University)
Kwon, Kang (Department of Ophthalmology, Otolaryngology and Dermatology, Pusan National University Korean Medicine Hospital)
Seo, Hyung-Sik (Department of Ophthalmology, Otolaryngology and Dermatology, Pusan National University Korean Medicine Hospital)
Publication Information
Journal of Pharmacopuncture / v.16, no.2, 2013 , pp. 7-14 More about this Journal
Abstract
Objective: The endpoint of this review is to investigate existing studies of Cervi cornu parvum (CCP) pharmacopuncture within Korean medicine journals in order to present a better research method in the future. Methods: We searched all the papers through six Korean electrical databases that included the title of "Cervi cornu parvum pharmacopuncture" or "Cervi cornu parvum aqua-acupuncture". Articles that had been published until December 2012 were largely divided into experimental studies and clinical studies. Results: Fifty-three (53) experimental studies and six clinical studies were found. The number of published articles has been constantly increasing. Many of the experimental studies demonstrated anti-inflammatory effects for arthritis, and most of the clinical studies dealt with musculoskeletal problems. Conclusion: Various therapeutically significant effects of the CCP pharmacopuncture have been found through this review; however, more systematic clinical studies on the CCP pharmacopuncture seem to be necessary to substantially support its clinical effects.
Keywords
aqua-acupuncture; Cervidae; deer antler; Korean medicine; pharmacopuncture; review;
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Times Cited By KSCI : 16  (Citation Analysis)
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1 Lee JY, Han YJ, Kim JH, Kim YJ, Kwon KR. [Type analysis of pharmacopuncture papers published in the Journal of Korean Institute of Pharmacopuncture]. Pharmacopuncture. 2006;9(3):147-52. Korean.   과학기술학회마을   DOI   ScienceOn
2 Bensky D, Gamble A. Chinese herbal medicine: materia medica. Revised ed. Seattle: Eastland Press; 1992. p. 32-44.
3 Choi MS, Ko HK, Kim CH. [The study of aquaacupuncture]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 1990;7(1):315-29. Korean.
4 Ahn HL, Yang MS, Shin MS, Choi JB, Kim SJ. [The experimental study of electroacupunture and Cervi pantotichum Cornu pharmacopuncture on pain decrease and nerve regeneration after crush injury of the sciatic nerve]. J Oriental Rehab Med. 2009;19(1):39-55. Korean.
5 Sul JU, Chu MK, Kim SJ, Choi JB, Shin MS, Kim SI. [Effects of Yanghyuljanggeungunbo-tang (Yangxuezhuangjinjianbu-tang) and electrical acupuncture on spinal nerve injury and motor function]. J Oriental Rehab Med. 2009;19(2):1-25. Korean.
6 Kim YJ, Park DS, Kang SG. [Studies on the analgesic effect of aqua-acupuncture with Cervus elaphus extract solution in mice]. The Journal of Korean Acupuncture & Moxibustion Medicine Society.1987;4(1):63-74. Korean.
7 Ko GI. [Effect of the antler (deer horn) water extract on the stress resistance in mice]. J Korean Pharm Sci. 1981;11(2):211-15. Korean.   과학기술학회마을
8 Seo JY, Um TS. [The effects of aqua-acupuncture with Cervus nippon Temminic at meridian point KyOksu (BL17) on RBC, Hgb, Hct in healthy person with four types of physical constitution]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 1995;11(2):219-29. Korean.
9 Ryu SH, Lee KM, Lee BH, Lim SC, Jung TY, Seo JC. [DNA and proteomic expression of Cervi Parvum Cornu herbal-acupuncture solution (CPC-HAS) in HepG2 carcinoma cells]. Pharmacopuncture. 2006;9(2):5-16. Korean.
10 Lee JM, Kim YT, Lee HI, Son YS, Jin SH, Lee HS, et al. [The effects of Cervus elaphus aquacupuncture and Gingseng radix aquacupuncture on the growth of animals]. Pharmacopuncture. 2000;3(2):131-52. Korean.   DOI   ScienceOn
11 Kim YT, Son YS, Jin SH, Han SW, Shim IS, Lim S, et al. [The effects of Cervus elaphus on the growth and the intellectual development of animals]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2001;18(5):122-34. Korean.   과학기술학회마을
12 Kim YW, Moon JY, Lim JK, Park WH, Park SD, Nam KS. [Effects of CCP (Cervi Cornu Parvum) aquaacupuncture on glucocorticoid-Induced immunosuppression in Murine Lymphocyte]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 1997;14(2):245-52. Korean.
13 Kim YW, Moon JY, Lim JK, Nam KS. [Effects of CCP (Cervi Cornu Parvum) aqua-acupuncture on MAHRP induced antibody production and lysozyme activity in mouse]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 1997;14(1):409-19. Korean.
14 Jang SJ, Lee CH, Yook TH. [Effects of Laennec.N. HO (Hominis placenta.Cervi Pantotrionum Cornu.Carthami semen) aqua-acupuncture on the ovariectomized osteoporotic rats]. The Journal of Korean Oriental Medicine. 1998;19(1):5-18. Korean.
15 Yoon CH, Jeung JC, Shin US. [Antioxidative effects of Cervus elaphus aqua-acupuncture on damage of rat's kidney induced by bromobenzene]. Korean J Orient Int Med. 1999;20(2):287-302. Korean.
16 Lee KB, Park SK. [Effects of Cornu Cervi Parvum pharmacopuncture on the blood picture and antioxidative activity in rats]. The Korean Journal of Meridian & Acupoint. 2010;27(2):25-34. Korean.   과학기술학회마을
17 Park JS, Kim WY, Baek ST, Lee SD, Kim KS. [The clinical observations of 4 cases of De Quervain's disease treated with Cervus elphus herbalacupuncture]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2004;21(6):259-68. Korean.
18 Seo JC, Yoon JS, Park HJ, Lee HJ, Han SW. [The clinical study on acupuncture sensation in CC, CF and BV herbal acupuncture - The basic study on placebo herbal acupuncture]. Pharmacopuncture. 2004;7(1):63-9. Korean.   DOI   ScienceOn
19 Yu MK, Bae JS, Park YH, Kim JH, Choi JH. [A case study of three patients who have tinnitus that is diagnosed as weakness of the kidney, treated with Cervi Pantotricuhum Cornu herbal-acupunture.] The Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology. 2006;19(2):249-55. Korean.   과학기술학회마을
20 Kim SJ, Sul JU, Kim SJ, Shin MS, Choi JB. [Clinical case report of polyneuritis: with Cervus elaphus herbal-acupuncture]. The Journal of Korea CHUNA Manual Medicine for Spine & Nerves. 2006;1(1):35-43. Korean.   과학기술학회마을
21 Kim WY, Paek ST, Park JS, Lee SD, Kim KS. [The clinical study of the herbal acupuncture on Tarsalgia and plantar faciitis]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2004;21(6):121-26. Korean.
22 Park EJ, Shin JC, Na GH, Lee DH, Han SG, Yoon YC, et al. [Study on clinical effects of Cervus elaphus herbal-acupuncture on osteoarthritis in knee joint]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2004;21(2):275-86. Korean.
23 Ryu HS, Kim SP, Chun HS, Ryu MS, Shin JC, Wei TS. [The comparative study of effects between acupuncture treatment and cotreatment with mixed pharmacopuncture of Jungsongouhyul and Cervi Pantotrichum Cornu on Low Back Pain Patients]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2011;28(6):149-57. Korean.   과학기술학회마을
24 Yoon CH, Jeong JC, Shin US. [Effects of Cervus elaphus for herb-acupuncture solution on antioxidation in rat's liver]. Journal of Korean Oriental Medicine. 1996;17(2):191-202. Korean.
25 Lee JH, Lee KM, Kim JS. [Anti-wrinkle effects of Cervi Pantotrichum Cornu pharmacopuncture solution]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2010;27(4):1-8. Korean.   과학기술학회마을
26 Yoon CH, Jeong JC, Shin US. [Effects of Cervuselaphus aqua-acupuncture's solution on damage of rat's kidney induced by ischemia and reflow]. Korean J Orient Int Med.1999;20(1):111-21.Korean.
27 Jeong JC. [Effects of Cervus elaphus extract solution for aqua-acupuncture on antioxidation in rat's brain induced by ischemia and reflow]. Korean J Orient Int Med. 1999;20(1):167-80. Korean.
28 Byun BH, Seo BI. [Safety study on genetic toxicity of Cervi Pantotrichum Cornu herbal acupuncture solution (CPCHA)]. Kor J Herbology. 2005;20(2):1-6. Korean.   과학기술학회마을
29 Byun BH, Seo BI. [Safety study on general cell cytotoxicity effects of Cervi Pantotrichum Cornu herbal-acupuncture solution (CPCHA)]. Korea J Herbology. 2003;18(3):51-6. Korean.   과학기술학회마을
30 Choi MK, Lee YH. [Studies on the safety assessment of Cervus elaphus extract for aquaacupuncture (antigenicity test)]. Journal of Korean Oriental Medicine. 1993;14(1):103-13. Korean.
31 Cho SH, Lee YH, Park YB. [Acute toxicity study of aqua-acupuncture of Cervi Cornu Parvum and Ganoderma Lucidum Karsten in mice]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 1992;9(1):71-83. Korean.   과학기술학회마을
32 Han SW, Lee YH, Kim CH. [A study on effects of the Cervi Pantotricuhum Cornu herb-acupuncture on the osteoporosis induced by ovariectomy in rats]. Pharmacopuncture. 2000;3(1):177-91. Korean.   과학기술학회마을   DOI   ScienceOn
33 Kim JK, Kim KS. [Effects of the pilose antler of Cervus Korean TEMMINCK var. mantchuricus Swinhoe (DAS), herbal acupuncture solution on suppression of collagenolysis and bone resorption in mouse calvarial osteoblasts]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2004;21(4):225-36. Korean.
34 Kim MJ, Lee SD, Kim KH, Byun H, Kim KS. [Effects of deer antler water extract (pilose antler of Cervus Korean TEMMINCK var. mantchuricus Swinhoe) on chondrocytes]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2004;23(2):103-11. Korean.   과학기술학회마을
35 Abadjieva DK, Kang SK. [Effect of Cervi Cornu aqua-acupuncture on lipid metabolism and osteoporosis in ovariectomized rats]. The Journal of Korean Oriental Medicine. 1996;17(2):168-77. Korean.
36 Kee YB, Kim DH, Kang DH, Kim SJ, Choi JB. [Effects of Yukmijihwang-tang (Liuweidihuang-tang) and Cervi Pantotrichum Cornu pharmacopuncture on fracture healing in diabetic rats]. J Oriental Rehab Med. 2012;22(3):49-63. Korean.
37 Yook TH, Lee CH, Lee HI. [A study on the effects of the Carthamisemen, Cervi Pantotrichum Cornu, Hominis placenta aquacupuncture on the osteoporosis in rats]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2001;18(1):61-75. Korean.
38 Han SW, Choi JY, Lee YH. [Healing of bony defects by Cervi Pantotricuhum Cornu herbal acupuncture]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2001;18(5):135-46. Korean.   과학기술학회마을
39 Ahn HJ, Kim KS. [Inhibitory effect of deer antler aqua-acupuncture (DAA) on cathepsin S activity and rheumatoid arthritis in rats]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2003;20(3):104-16. Korean.
40 Kim EJ, Kim GY, Cung HW. [Effect of Achyrantis Radix administration and Cervi Cornu Parvum acupuncture in experimental osteoarthritis rats]. Korean J Oriental Physiology & Pathology. 2007;21(5):1194-99. Korean.
41 Kim JG, Kim KS. [Inhibitory effects of Cervi Pantotrichum Cornu herbal acupuncture on type-II collagen-induced arthritis]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2002;19(6):155-70. Korean.
42 Choi YH, Choi WS, Song IK, Park JS, Lee SD, Kim KS. [Protective and anti-arthritic effects of Cervi Pantotrichum Cornu herbal acupuncture, inhibiting Dihydroorotate Dehydrogenase, on Phosphate-ion-mediated Chondrocyte Apoptosis and rat collagen-induced arthritis]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2002;19(5):10-27. Korean.
43 Choi BJ, Kim MJ, Park SD, Lee AR, Jang JH, Kim KH. [Modulation of bone mass, strength and turnover by a Cervi Pantotrichum Cornu herbal acupuncture in adjuvant-induced arthritic rats]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2002;19(5):219-33. Korean.
44 Lee HY, Lee JB, Cho YH, Song BY, Yook TH. [The effects of Cervi Pantotrichum Cornu pharmacopuncture and Bovis Calculus.FelUrsi pharmacopuncture on the heart rate variability]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2010;27(1):65-74. Korean.
45 Lee SM, Ahn BC, Lee YH. [Study of the effects of aqua-acupuncture with Ginseng radix, Cervi Cornu and Saussureae radix extract solution on the weight increase and secretion of gastric hormone in mice]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 1988;5(1):1-13. Korean.
46 Han SW, Seo JC, Lee YH, Choi JY. [Gene expression analysis using cDNA microarray assay by Cervi Pantotricuhum Cornu herbal acupuncture]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2003;20(3):34-44. Korean.
47 Yong JI, Pack NH. [Studies on deer horn (I) : free amino acids of deer horn water extract]. Yakhak Hoeji. 1960;5(1):1-2. Korean.   과학기술학회마을
48 Kim HJ, Song BY, Yook TH. [The effects of distilled Cervi Pantotrichum Cornu pharmacopuncture and Zzizyphispinosi semen pharmacopuncture on the heart rate variability]. Pharmacopuncture. 2009;12(3):31-40. Korean.
49 Lee SJ, Jeong HW. [Effects of pharmacopuncture therapy using Cervi Pantotrichum Cornu at BL23, BL52 on the cerebral hemodynamics in rats]. Korean J Oriental Physiology & Pathology. 2009;23(1):50-6. Korean.
50 Kim SO, Yoon DH, Na CS. [Effect of Cervus elaphus herbal acupuncture on focal ischemia induced by inserted intraluminal filament in MCA of rats]. The Korean Journal of Meridian & Acupoint. 2005;22(4):67-81. Korean.   과학기술학회마을
51 Ryu SH, Lee KM, Lee BH, Lim SC, Jun TY, Seo JC. [Oligonucleotide chip analysis of Cervi Parvum Cornu herbal-acupuncture solution (CPC-HAS) on SNU484 carcinoma cells]. The Korean Journal of Meridian & Acupoint. 2006;23(2):137-48. Korean.
52 Park SD, Kim MJ, Lee AR, Jang JH, Kim KH. [Effect of Cervi Pantotrichum Cornu herbal acupuncture on protease activities, antioxidant in rheumatoid arthritis rats]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2002;19(2):51-64. Korean.
53 Kwak DG, Yang CH. [A regulatory effect of Cervi Cornu Parvum aqua-acupuncture on serum estradiol level after ovariectomy]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 1998;15(2):29-41. Korean.   과학기술학회마을
54 Yang HT, Yoon JW, Kim KS, Song CH, Ahn CB. [Study of effect of Cervus Nippon Temminck aquaacupuncture on the hypothyroidism induced by thiourea in rats]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 1992;9(1):215-27. Korean.
55 Kim KR. Lee YH. [A study of the effect of Cervus elapus aqua-acupuncture on the adrenal cortical insufficiency in rats]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 1987;4(1):49-62. Korean.
56 Hwang JS, Hwang JH, Lee HJ, Lee DG, Kang MJ, Back SO, et al. [The ability of Cervus Elaphus Sibiricus herbal acupuncture to inhibit the generation of inflammatory enzymes on collageninduced arthritis mice]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2007;24(6):1-14. Korean.
57 Kim JK, Lee SD, Jeong YR, Kim KS. [Protective action of cartilage and bone destruction by deer antler herbal-acupuncture solution, the pilose antler of Cervus Korean TEMMINCK Var. Mantchuricus Swinhoe, on Type-II collageninduced arthritis in mice]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2006;23(2):73-90. Korean.
58 Kim WY, Lee SD, Kim KH, Baek ST, Kim KS. [The efficiency of deer antler herbal acupuncture on modulation and prevention of IL-1 mediated activation in rat chondrocytes at a receptor level]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2006;23(2):113-23. Korean.   과학기술학회마을
59 Korean Pharmacopuncture Institute. Pharmacopuncturology: principles and clinical applications. Seoul: Elsevier Korea LLC; 2012. Chapter 01, Definition and history; p. 3.
60 Kim SH, Kim KS. [Effect of Cervi Cornu Parvum aqua-acupuncture in contents of female sexual hormone of women and osteoporotic change in ovariectomized rats]. The Journal of the Korea Institute of Oriental Medical Informatics. 1997;3(1):95-122. Korean.   과학기술학회마을
61 Lee JH, Jo DC, Moon SJ, Kong JC, Park TY, Ko YS, et al. [Narrative review of clinical trial on Hominis placenta pharmacopuncture in Korean literature]. J Oriental Rehab Med. 2012;22(3):79-88. Korean.
62 Kang CK, Kim SW. [A study on the biochemical and nutritional inquiry of antler]. Korean J Food & Nutr. 1989;2(2):65-71. Korean.   과학기술학회마을
63 Wu F, Li H, Jin L, Li X, Ma Y, You J, et al. Deer antler base as a traditional Chinese medicine: A review of its traditional uses, chemistry and pharmacology. J Ethnopharmacol. 2013;145(2):403-15.   DOI   ScienceOn
64 Kim WY, Choi JB. [Effects of bee venom and Cervi Corvu Parvum pharmacopuncture in monosodium iodoacetate (MIA)-induced osteoarthritis rat]. J Oriental Rehab Med. 2010;20(1):61-77. Korean.
65 Lee HJ, Cho HS, Hwang MS, Jung CY, Lee DG, Kim EJ, et al. [Effect of Cervi Pantotrichum Cornu pharmacopuncture on suppressing the expression of iNOS and production of NO in type-II collageninduced arthritis mice]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2008;25(5):105-16. Korean.   과학기술학회마을
66 Chung YR, Lee SD, Byun H, Park IS, Jung CY, Lee CH, et al. [The effect of deer antler herbal acupuncture control to hyper-inflammatory responses on synovial membrane by LPS-induced arthritis]. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 2007;24(4):167-81. Korean.   과학기술학회마을