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http://dx.doi.org/10.3831/KPI.2010.13.3.005

Biological Activities of Scolopendrid Pharmacopuncture  

Kim, Sung-Chul (Dept. of Acupuncture & Moxibustion, Gwang-Ju Oriental Medical Hospital, Wonkwang University)
Seo, Geun-Young (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University)
Lee, Sung-Won (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University)
Park, Sung-Joo (Dept. of herbology, school of Oriental Medicine, Wonkwang University)
Kim, Jae-Hyo (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University)
Ahn, Seong-Hun (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University)
Hwang, Sung-Yeoun (Korea Bio Medical Science institute)
Publication Information
Journal of Pharmacopuncture / v.13, no.3, 2010 , pp. 5-13 More about this Journal
Abstract
Reactive Oxygen Species(ROS) are continuously produced at a high rate as a by-product of aerobic metabolism. Since tissue damage by free radical increases with age, the reactive oxygen species(ROS) such as hydrogen peroxide($H_2O_2$), nitric oxide(NO). Several lines of evidence provided that ROS appears to cause to develop aging-related various diseases such as cancer, arthritis, cardiovascular disease. Our reserch objective was to examine the in vitro biological activity of Scolopendrid Pharmacopuncture, including the total poly-phenol content, DPPH radical scavenging, ABTS radical scavenging, Superoxide dismutase(SOD)-like activity, Nitrite scavenging ability. The total poly-phenol contents of Scolopendrid Pharmacopuncture was 35.859mg/L. Elctron donation ability on DPPH was 36.82%. The 2,2'-azinobis-3-ehtlbezothiazoline-6-sulfonic acid radical decolorization (ABTS) was 84.7%. The superoxide dismutase (SOD)-like activities of Scolopendrid Pharmacopuncture was 44.33%. The nitrite scavenging effects were pH dependent, and were highest at pH 1.5(45.2%) and lowest at pH 6.0(11.3%). We conclude that Scolopendrid Pharmacopuncture may be useful as potential sources of antioxidant.
Keywords
Scolopendrid Pharmacopuncture; nitrite scavenging ability; SOD-like activity; antioxidant activity;
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Times Cited By KSCI : 17  (Citation Analysis)
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