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http://dx.doi.org/10.3831/KPI.2010.13.2.005

Biological Activities of Hominis Placenta Herbal Acupuncture prepared by Hydrochloric Acid Hydrolysis  

Seo, Geun-Young (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University)
Lee, Sung-Won (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University)
Park, Sung -Joo (Dept. of Herbology, school of Oriental Medicine, Wonkwang University)
Kim, Sung-Chul (Dept. of Acupuncture & Moxibustion, Gwang-Ju Oriental Medical Hospital, Wonkwang University)
Sohn, In-Chul (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University)
Hwang, Sung-Yeoun (Korea Bio Medical Science institute)
Ahn, Seong-Hun (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University)
Publication Information
Journal of Pharmacopuncture / v.13, no.2, 2010 , pp. 5-12 More about this Journal
Abstract
Reactive Oxygen Species(ROS) are continuously produced at a high rate as a by-product of aerobic metabolism. Since tissue damage by free radical increases with age, the reactive oxygen species(ROS) such as hydrogen peroxide($H_2O_2$), nitric oxide(NO). Several lines of evidence provided that ROS appears to cause to develop aging-related various diseases such as cancer, arthritis, cardiovascular disease. In this study, we have conducted to investigate the biological activities of Hominis Placenta Herbal Acupuncture by measuring total polyphenol content, DPPH radical scavenging, ABTS radical scavenging, Superoxide dismutase(SOD)-like activity, Nitrite scavenging ability in vitro. The total polyphenol contents of Hominis Placenta Herbal Acupuncture was $24.6m{\ell}/m{\ell}$. Elctron donation ability on DPPH was 49.4%. The 2,2'-azinobis-3-ehtlbezothiazoline-6-sulfonic acid radical decolorization (ABTS) was 50.01%, similar 10 the DPPH free radical scavenging. The superoxide dismutase (SOD)-like activities of hominis placenta herbal acupuncture was 50.876%. The nitrite scavenging abilities at pH 1.5, pH 3.0, pH 6.0 were 52.8%, 29.4%, 15.4%, respectively; these abilities decreased as pH increased. We conclude that Hominis Placenta Herbal Acupuncture may be useful as potential sources of antioxidant.
Keywords
Hominis Placenta Herbal Acupuncture; nitrite scavenging ability; SOD-like activity; antioxidant activity;
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Times Cited By KSCI : 16  (Citation Analysis)
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1 Shin JH, Lee JY, Cho HS, Lee SJ, Jung KH and Sung NJ. Screening of effective factor to inhibition of NDMA formation in Yuza (Citrus junos). J Fd Hyg Safety. 2004;19:126-131.   과학기술학회마을
2 NJ. Miller, C Rice-Evans, MJ. Davies, V. Copinaththan and A. Milner. A novel method for measuring anti-oxidant capacity and its application to monitoring the antioxidant status in premature neonants. Clicical Science. 1993;26:265-277.
3 Rice-Evans CA, Miller NJ, Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med. 1993;20:933-956.   DOI   ScienceOn
4 Kim JE, Joo SI, Seo JH, and Lee SP. Antioxidant and ${\alpha}-Glucosidase Inhibitory effect of Tartary Buckwheat extract Obtained by the Treatment of Different Solvents and Enzymes. Korean J. Soc Food Sci Nutr.2009;38(8):989-995.   과학기술학회마을   DOI   ScienceOn
5 Ding AH, Nathan CF, Stuhr DJ. Realease of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. J. Immunol.1988;141:2407-2412.
6 Park SJ, Song SW, Seong DH, Park DS, Kim SS, Gou JY, Ahn JH, Yoon WB, Lee HY. Biological Activities in the extract of Fermented Codonopsis lanceolata. J. Korean Soc Food Sci Nutr. 2009;38(8):983-988.   과학기술학회마을   DOI   ScienceOn
7 Kwon HJ and Park CS. Biological Activities of extract from Omija. Korean J. Food Preserv. 2008;15(5):587-592.
8 Park CS, Kim DH and Kim ML. Biological activities of extract from Corni fructus, Astragalus membranaceus and Glycyrrhiza uralensis. Kor. J. Herbology. 2008;23:93-101.
9 Park CS and Kim DH. 2008. Biological Activities of Extracts from scutellaria baicalensis, Zizyphus jujuba and Atractylodes macrocepphala. Kor. J. Herbology. 2008 ;23(3):41-51.
10 Lim SC, Seo JC, Lee KM, Lee BH, Lee YK, Jung TY and Lee H. Scavenging effect of Hominis Placenta Herbal Acupunture Solution on Nitric Oxide. The Joumal of Korean Acupuncture & Moxibustion Society. 2007;08.   과학기술학회마을
11 Madsen HL, Andersen CM, Jorgensen LV. Radical scavenging by dietary flavonoids. Eur Food Technol. 2000;211:240-246.   DOI
12 Madsen HL, Nielsen BR, Bertelsen G, Skibsted LH. Screen of antioxidative activity of spices. Food Chem. 1996;57:331-377.   DOI   ScienceOn
13 Kwon TD, Choi SW, Lee SJ, Chung KW, and Lee SC. Effect of polyphenol or vitamin C ingestion on antioxidative activity during exercise in rats. Kor. J. Physical Education. 2001;3:891-899.
14 Kim HJ, Jun BS, Kim SK, Cha JY, Cho YS. polyphenolic compound content and antioxidative activities by extract from seed, sprout and flower of safflower. J. Korean Soc. Food Sic. Nutr. 2000;29:1127-1132.   과학기술학회마을
15 Kim EY, Baik IH, Kim JH, Kim SR, and Rhyu MG. Screening of the antioxidant activity of some medicinal plants. Korean J. Food Sic, Thechnol. 2004;36:338-338.   과학기술학회마을
16 Lee YS, Joo EY, and Kim NW. Polyphenol Contents and Physiological Activity of the Lespedeza bicolor Extracts. Korean J. Food preserv. 2006;13(5):616-622. October.   과학기술학회마을
17 Choi CH, Song ES, Kim JS, Kang MH, Antioxidative activites of castanea crenta Flos. methanol extracts. Korean J. Food sci. Techol. 2003;35:1216-1220.
18 Kuramoto T. Development and application of food materials from extract such as SOD. Upto data Food Process. 1992;27:22-23.
19 Kwon HJ, Park CS. 2008. Biological Activities of Extracts from Omija. Korean J. Food Preserv. 2008;15(4):587-592, August.   과학기술학회마을
20 Yoo KM, Kim DO, Lee CY. Evaluation of different methods of antioxidant measurement. Food Sci Biotechnol. 2007;16:177-182.   과학기술학회마을
21 Chang SY, Kim HJ, Lee DY, Lee EY. Effect of Hominis Placenta Herbal Acupuncture on Dysmenorrhea. The Joumal of Korean Acupuncture & Moxibustion Society. 2005;22(6):85-92.   과학기술학회마을
22 Bae RN, Lee SK. Factors affecting browing and its control methods in chopped garlic. J. Korean Soc. Hort. Sci. 1990;31:213-218.
23 Liu X, Sun L, Xiao J, Yin S, Liu C, Li Q, Li H, Jin B. Effect of acupunture and point-injection treatment on immunologic function in rheumatoid arthritis. J Tradit Chin Med. 1993;13(3):174-178.
24 Dewanto V, Wu X, Adonm KK, Liu PH. Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity. J Agric Food Chem. 2002;50:3010-3014.   DOI   ScienceOn
25 Dietz BM, Kang YH, Liu G, Eggler AL, Yao P, Chadwick LR, Pauli GF, Famsworth NR, Mesecar AD, van Breemen RB, and Bolton JL. Xanthohumol isolated from Humulus lupulus inhibits menadione-induced DNA damage through induction of quinone reductase. Chem Res Toxicol. 2005;18:1296-1305.   DOI   ScienceOn
26 Jo KS, Kim HK, Ha JH, Park MH, Shin HS. Flavor compounds and storage stability of essential oil from garlic distillation. Korean J. Food Sci. Technol. 1990;22:50-55.   과학기술학회마을
27 Marklund S, Marklund G. Involvement of superoxide anion radical in the oxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 1974;47:469-474.   DOI   ScienceOn
28 Venden Berg R, Haenen GR, Van den Berg H, Bast A. Applicability of an improved Trolox equivalent anti-oxidant capacity (TEAC) assay for evaluation of anti-oxidant capacity measurements of mixture. Food Chem. 1999;66:511-517.   DOI   ScienceOn
29 Kato H, Lee IE, Chuyen NV, Kim SB, Hayase F. Inhubutuon of nitrosamine formation by nondialyzable melanoidins. Agr. Biol. Chem. 1987;51:1333-1338.   DOI
30 주혜정, 황재옥. 한국한의학연구원 기타 간행물 21세기 한의학. 1995;5:193-210.
31 Yin CS, Koh HG. The documental record on bee venom therapy in Oriental medicine: 2 prescriptions of bee venom in the ancient Mawangdui books of Oriental medicine. J Korean Acupunture & Moxibustion. 1998;15(1):143-147.
32 전국한의과대학본초학교수 공편. 본초학. 서울 영림사. 1992;567-568.
33 장종범. 자하거에 대한 고찰. 대한한의학회지. 1965;3(5):36-38.
34 Yook TH, Lee CH, Lee HI. A Study on the effects of the Carthami semen, Cervi pomtotrichum cornu, Hominis placenta aquacupuncture on the osteoporosis in the rats. The Joumal of Korean Acupuncture & Moxibustion Society. 2001;18(1):61-75.
35 Park KB, Song KH, Lee JS, Jo JH. Study on Clinical Effects of Homnis Placenta Herbal Acupuncture on Osteoarthritis of Knee Joint. The Joumal of Korean Acupuncture & Moxibustion Society. 2006;23(4)163-173.   과학기술학회마을
36 Lee JH, Kim YH, Yook TH, Lee EY, Kim EH. The Clinical Observation of Peripheral facial paralysis used Aqua-acupuncture treatment. The Joumal of Korean Acupuncture & Moxibustion Society. 2002;19(1):11-23.