Browse > Article

Epidemiologic Study of Clonorchis Sinensis Infestation in a Rural Area of Kyongsangnam-do, South Korea  

Ju, Young-Hee (Cancer Cohort Study Branch, Research Institute for National Cancer Control & Evaluation, National Cancer Center)
Oh, Jin-Kyoung (Cancer Cohort Study Branch, Research Institute for National Cancer Control & Evaluation, National Cancer Center)
Kong, Hyun-Joo (Cancer Cohort Study Branch, Research Institute for National Cancer Control & Evaluation, National Cancer Center)
Sohn, Woon-Mok (Department of Parasitology and Institute of Health Sciences, Gyeongsang National University College of Medicine)
Kim, Yoon-Gyu (Department of Occupational Medicine, College of Medicine, Dong-A University)
Kim, Jung-Il (Department of Occupational Medicine, College of Medicine, Dong-A University)
Jung, Kap-Yeol (Department of Occupational Medicine, College of Medicine, Dong-A University)
Shin, Hai-Rim (Cancer Cohort Study Branch, Research Institute for National Cancer Control & Evaluation, National Cancer Center)
Publication Information
Journal of Preventive Medicine and Public Health / v.38, no.4, 2005 , pp. 425-430 More about this Journal
Abstract
Objectives : To investigate the prevalence of Clonorchis Sinensis infestation and to determine the associated risk factors among a population in a part of the rural area of Gyeongsangnam-do, Korea, which is an area known to have a high mortality from liver cancer and a high infection of C. sinensis. Methods : The study populat ion consisted of those people who have lived in rural areas and who were over 40 years old. This study was performed in 5 areas during the period from 1999 to 200 3. Informed consents were obtained from the 2,381 study participants, and these people were interviewed about their life style habits with using the structured questionnaire that was administered by trained staff members. The subjects underwent blood sampling and their stool specimens were examined by using the Formalin-ether sedimentation technique. Results : Among the study subjects (N=2,381), the positivity for C. sinensis in the stool was 34.4% (95% CI=36.3-42.5); it was 39.4% (95% CI=36.3-42.5) in the males and 30.9% (95% CI=28.5-33.3) in the females . The positivity for C. sinensis was associated with current alcohol drinking (odds ratio=1.8, 95% CI: 1.5-2.1) and raw fish consumption (odds ratio 1.2, 95% CI: 0.9-1.6). Conclusion : The present study confirmed the high prevalence of C. sinensis in the study subjects. It is necessary to establish consistent medical management and education programs for the treatment and prevention of C. sinensis infestation in the rural inhabitants of Korea.
Keywords
Clonorchis sinensis; Stool examination; Korea;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Chen M, Lu Y, Hua X, Mott KE. Progress in assessment of morbidity due to Clonorchis sinensis infection; a review of recent literature. Trop Dis Bull 1994; 91(3): R7-R65
2 Korea National Statistical Office. Annual Report on the Cause of Death Statistics; 2002 (Korean)
3 Hwang MH, Kim SI, Park J, Ryu SY, Lee CG, Ahn HO, Kim YO, Kim KS. The prevalence of clonrchis sinensis and its related factors at Goksung area in the basin of Sumjin river. Korean J Rural Med 1997; 22(2): 239-252 (Korean)
4 김충현. 간흡충증의 충란 검사법 비교에 관한 연구. 서울대학교 대학원 석사학위논문; 2004
5 WHO, IARC. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Vol 61 Schistosomes, Live Flukes and Helicobacotr Pylori: IARC; 1994
6 Rim HJ. The current pathobiology and chemotherapy of clonorchiasis. Kisaengchunghak Chapchi 1986; 24 Suppl: 1-141   DOI
7 Loh IK. The present status and a proposal of the prospective measures for parasitic diseases control in Korea. Korea J Prev Nutr 1970; 3(1): 1-16 (Korean)
8 Bae KH, Ahn YK, Soh CT, Tsutsumi H. Epidemiological Studies on Clonorchis sinensis Infection along the Nam-River in Gyeongnam province, Korea. Korean J Parasitol 1983; 21: 167-186 (Korean)   DOI
9 Kim SI, Oh GJ, Park H. A seroepidemiological survey for human clonrchiasis on Soonchanggun near Sumjin river in Korea. Korean J Rural Med 2002; 27(2): 27-33 (Korean)
10 Park EM. The infection status and perception toward intestinal trematodes of an island inhabitants [dissertation]. Korea: Chosun Univ; 2000 (Korean)
11 Kim SI, Park J, Kim KS, Yang AH, Kim YL. An evaluation on the prevalence of and reinfection after medicine of patients with clonrchis sinensis in an endemic locality. Korean J Rural Med 1999; 24(2): 225-232 (Korean)
12 Lee DH, Kim JH, Han BH, Lee SO, Shin HR, Jung IC. Geographical variation of liver cancer mortality in Korea. Cancer Res Treatment 2001; 33(5): 420-426 (Korean)
13 Sohn WM, Cho YP, Kim KJ, Kim MY, Lee CW, Park DH. Analysis on the findings of serum biochemical test in inhabitants infected with Clonorchis sinensis. J Biomed Lab Sci 2001; 7(1): 39-45 (Korean)
14 Song HY, Lee KS, Lee ST, Kim DK, Ahn DS. Clinical feature in clonorchiasis. Korean J Gastrol 1995; 27(1): 64-71 (Korean)
15 Lee JS, Lee WJ, Kim TS, In TS, Kim WS, Kim SK. Current status and the changing pattern of the prevalence of clonorchiasis in the inhabitants in Sanchong-gun, Kyongsangnam-do, Korea. Korean J Parasitol 1993; 31: 207-213 (Korean)   DOI   ScienceOn
16 Chai JY, Yang YT, Lee SH, Seo BS. The detectability of helminth eggs from feces by cellophane thick smear technique. Kisaengchunghak Chapchi 1982; 20: 14-20   DOI
17 Kim CH, Na YE, Kim NM, Shin DW, Chang DY. Intestinal parasite and Clonorchis sinensis infection among the inhabitants in the upper stream of Taechong Dam, Kumgang (River). Korean J Parasitol 1994; 32: 207-214 (Korean)   DOI   ScienceOn
18 The Ministry of Health and Welfare, Korea Association of Health Promotion. Prevenlance of Intestinal Parasitic Infection in Korea; 1997, The Sixth Report (Korean)
19 Seo BS, Lee SH, Cho SY, Chai JY, Hong ST, Han IS, Sohn JS, Cho BH, Ahn SR, Lee SK, Chung SC, Kang KS, Shim HS, Hwang IS. An epidemiologic study on clonorchiasis and metagonimiasis in riverside areas in Korea. Korean J Parasitol 1981; 19: 137-150 (Korean)   DOI
20 Choi MS. Diagnostic usefulness of sonography according to prevalence and intensity of Clonorchis sinensis infection [dissertation]. Korea: Seoul National Univ; 2004 (Korean)