Recent technological updates and clinical applications of induced pluripotent stem cells |
Diecke, Sebastian
(Division of Cardiology, Department of Medicine, Stanford University School of Medicine)
Jung, Seung Min (Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) Lee, Jaecheol (Division of Cardiology, Department of Medicine, Stanford University School of Medicine) Ju, Ji Hyeon (Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) |
1 | Somorjai IM, Lohmann JU, Holstein TW, Zhao Z. Stem cells: a view from the roots. Biotechnol J 2012;7:704-722. DOI ScienceOn |
2 | Zaehres H, Scholer HR. Induction of pluripotency: from mouse to human. Cell 2007;131:834-835. DOI ScienceOn |
3 | Grskovic M, Javaherian A, Strulovici B, Daley GQ. Induced pluripotent stem cells: opportunities for disease modelling and drug discovery. Nat Rev Drug Discov 2011;10:915-929. |
4 | Schugar RC, Robbins PD, Deasy BM. Small molecules in stem cell self-renewal and differentiation. Gene Ther 2008;15:126-135. DOI ScienceOn |
5 | Murry CE, Keller G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 2008;132:661-680. DOI ScienceOn |
6 | Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-676. DOI ScienceOn |
7 | Maherali N, Sridharan R, Xie W, et al. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 2007;1:55-70. DOI ScienceOn |
8 | Jaenisch R, Young R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 2008;132:567-582. DOI ScienceOn |
9 | Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-872. DOI ScienceOn |
10 | Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007;318:1917-1920. DOI ScienceOn |
11 | Chang CW, Lai YS, Pawlik KM, et al. Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells. Stem Cells 2009;27:1042-1049. DOI ScienceOn |
12 | Feng B, Ng JH, Heng JC, Ng HH. Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. Cell Stem Cell 2009;4:301-312. DOI ScienceOn |
13 | Gonzalez F, Boue S, Izpisua Belmonte JC. Methods for making induced pluripotent stem cells: reprogramming a la carte. Nat Rev Genet 2011;12:231-242. DOI ScienceOn |
14 | Heinrich EM, Dimmeler S. MicroRNAs and stem cells: control of pluripotency, reprogramming, and lineage commitment. Circ Res 2012;110:1014-1022. DOI ScienceOn |
15 | Kretsovali A, Hadjimichael C, Charmpilas N. Histone deacetylase inhibitors in cell pluripotency, differentiation, and reprogramming. Stem Cells Int 2012;2012:184154. |
16 | Zhou H, Wu S, Joo JY, et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009;4:381-384. DOI ScienceOn |
17 | Bayart E, Cohen-Haguenauer O. Technological overview of iPS induction from human adult somatic cells. Curr Gene Ther 2013;13:73-92. DOI |
18 | Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K. Induced pluripotent stem cells generated without viral integration. Science 2008;322:945-949. DOI ScienceOn |
19 | Stadtfeld M, Hochedlinger K. Induced pluripotency: history, mechanisms, and applications. Genes Dev 2010;24:2239-2263. DOI ScienceOn |
20 | Jia F, Wilson KD, Sun N, et al. A nonviral minicircle vector for deriving human iPS cells. Nat Methods 2010;7:197-199. DOI ScienceOn |
21 | Warren L, Manos PD, Ahfeldt T, et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010;7:618-630. DOI ScienceOn |
22 | Hayden EC. California ponders cell-banking venture. Nature 2011;472:403. DOI ScienceOn |
23 | Fusaki N, Ban H, Nishiyama A, Saeki K, Hasegawa M. Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci 2009;85:348-362. DOI ScienceOn |
24 | Gonzalez F, Barragan Monasterio M, Tiscornia G, et al. Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector. Proc Natl Acad Sci U S A 2009;106:8918-8922. DOI ScienceOn |
25 | Dowey SN, Huang X, Chou BK, Ye Z, Cheng L. Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression. Nat Protoc 2012;7:2013-2021. DOI ScienceOn |
26 | Yu J, Hu K, Smuga-Otto K, et al. Human induced pluripotent stem cells free of vector and transgene sequences. Science 2009;324:797-801. DOI ScienceOn |
27 | Ban H, Nishishita N, Fusaki N, et al. Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc Natl Acad Sci U S A 2011;108:14234-14239. DOI ScienceOn |
28 | Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S. Generation of mouse induced pluripotent stem cells without viral vectors. Science 2008;322:949-953. DOI ScienceOn |
29 | Diecke S, Lisowski L, Mordwinkin NM, Kooreman NG, Wu JC. Second generation codon optimized minicircle (Comic) for non-viral reprogramming of human adult fibroblasts. In: Radisic M, Black LD 3rd, eds. Cardiac Tissue Engineering: Methods and Protocols. Vol. 1181. New York: Humana Press, 2014. |
30 | Lu J, Zhang F, Xu S, Fire AZ, Kay MA. The extragenic spacer length between the 5' and 3' ends of the transgene expression cassette affects transgene silencing from plasmid-based vectors. Mol Ther 2012;20:2111-2119. DOI |
31 | Chen ZY, He CY, Ehrhardt A, Kay MA. Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo. Mol Ther 2003;8:495-500. DOI ScienceOn |
32 | Narsinh KH, Jia F, Robbins RC, Kay MA, Longaker MT, Wu JC. Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors. Nat Protoc 2011;6:78-88. |
33 | Mandal PK, Rossi DJ. Reprogramming human fibroblasts to pluripotency using modified mRNA. Nat Protoc 2013;8:568-582. DOI |
34 | Lu J, Zhang F, Kay MA. A mini-intronic plasmid (MIP): a novel robust transgene expression vector in vivo and in vitro. Mol Ther 2013;21:954-963. DOI |
35 | Hung SC, Kang MS, Kieff E. Maintenance of Epstein- Barr virus (EBV) oriP-based episomes requires EBV-encoded nuclear antigen-1 chromosome-binding domains, which can be replaced by high-mobility group-I or histone H1. Proc Natl Acad Sci U S A 2001;98:1865-1870. DOI |
36 | Warren L, Ni Y, Wang J, Guo X. Feeder-free derivation of human induced pluripotent stem cells with messenger RNA. Sci Rep 2012;2:657. DOI |
37 | Okita K, Yamakawa T, Matsumura Y, et al. An efficient nonviral method to generate integration-free human- induced pluripotent stem cells from cord blood and peripheral blood cells. Stem Cells 2013;31:458-466. DOI ScienceOn |
38 | Colamonici OR, Domanski P, Sweitzer SM, Larner A, Buller RM. Vaccinia virus B18R gene encodes a type I interferon-binding protein that blocks interferon alpha transmembrane signaling. J Biol Chem 1995;270:15974-15978. DOI ScienceOn |
39 | Amit M, Winkler ME, Menke S, et al. No evidence for infection of human embryonic stem cells by feeder cell-derived murine leukemia viruses. Stem Cells 2005;23:761-771. DOI ScienceOn |
40 | Yoshioka N, Gros E, Li HR, et al. Efficient generation of human iPSCs by a synthetic self-replicative RNA. Cell Stem Cell 2013;13:246-254. DOI ScienceOn |
41 | Kim D, Kim CH, Moon JI, et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 2009;4:472-476. DOI ScienceOn |
42 | Lee J, Sayed N, Hunter A, et al. Activation of innate immunity is required for efficient nuclear reprogramming. Cell 2012;151:547-558. DOI ScienceOn |
43 | Ding Q, Lee YK, Schaefer EA, et al. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell 2013;12:238-251. DOI ScienceOn |
44 | Hou P, Li Y, Zhang X, et al. Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science 2013;341:651-654. DOI ScienceOn |
45 | Zwaka TP, Thomson JA. Homologous recombination in human embryonic stem cells. Nat Biotechnol 2003;21:319-321. DOI ScienceOn |
46 | Hockemeyer D, Soldner F, Beard C, et al. Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nat Biotechnol 2009;27:851-857. DOI ScienceOn |
47 | Robinton DA, Daley GQ. The promise of induced pluripotent stem cells in research and therapy. Nature 2012;481:295-305. DOI ScienceOn |
48 | Horii T, Morita S, Kimura M, et al. Genome engineering of mammalian haploid embryonic stem cells using the Cas9/RNA system. PeerJ 2013;1:e230. DOI ScienceOn |
49 | Cheng LT, Sun LT, Tada T. Genome editing in induced pluripotent stem cells. Genes Cells 2012;17:431-438. DOI ScienceOn |
50 | Kim H, Kim JS. A guide to genome engineering with programmable nucleases. Nat Rev Genet 2014;15:321-334. DOI ScienceOn |
51 | Tiscornia G, Vivas EL, Izpisua Belmonte JC. Diseases in a dish: modeling human genetic disorders using induced pluripotent cells. Nat Med 2011;17:1570-1576. DOI |
52 | Urbach A, Schuldiner M, Benvenisty N. Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells. Stem Cells 2004;22:635-641. DOI ScienceOn |
53 | Park IH, Arora N, Huo H, et al. Disease-specific induced pluripotent stem cells. Cell 2008;134:877-886. DOI ScienceOn |
54 | Yazawa M, Hsueh B, Jia X, et al. Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. Nature 2011;471:230-234. DOI ScienceOn |
55 | Dimos JT, Rodolfa KT, Niakan KK, et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 2008;321:1218-1221. DOI ScienceOn |
56 | Urbach A, Bar-Nur O, Daley GQ, Benvenisty N. Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell 2010;6:407-411. DOI ScienceOn |
57 | Carvajal-Vergara X, Sevilla A, D'Souza SL, et al. Patient- specif ic induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 2010;465:808-812. DOI ScienceOn |
58 | Itzhaki I, Maizels L, Huber I, et al. Modelling the long QT syndrome with induced pluripotent stem cells. Nature 2011;471:225-229. DOI ScienceOn |
59 | Jang J, Kang HC, Kim HS, et al. Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients. Ann Neurol 2011;70:402-409. DOI ScienceOn |
60 | Brennand KJ, Simone A, Jou J, et al. Modelling schizophrenia using human induced pluripotent stem cells. Nature 2011;473:221-225. DOI ScienceOn |
61 | Perel P, Roberts I, Sena E, et al. Comparison of treatment effects between animal experiments and clinical trials: systematic review. BMJ 2007;334:197. DOI ScienceOn |
62 | Frey-Vasconcells J, Whittlesey KJ, Baum E, Feigal EG. Translation of stem cell research: points to consider in designing preclinical animal studies. Stem Cells Transl Med 2012;1:353-358. DOI ScienceOn |
63 | Kramer AS, Harvey AR, Plant GW, Hodgetts SI. Systematic review of induced pluripotent stem cell technology as a potential clinical therapy for spinal cord injury. Cell Transplant 2013;22:571-617. DOI ScienceOn |
64 | Saha K, Jaenisch R. Technical challenges in using human induced pluripotent stem cells to model disease. Cell Stem Cell 2009;5:584-595. DOI ScienceOn |
65 | Kola I, Landis J. Can the pharmaceutical industry reduce attrition rates? Nat Rev Drug Discov 2004;3:711-715. DOI ScienceOn |
66 | Irion S, Nostro MC, Kattman SJ, Keller GM. Directed differentiation of pluripotent stem cells: from developmental biology to therapeutic applications. Cold Spring Harb Symp Quant Biol 2008;73:101-110. DOI ScienceOn |
67 | Zhu H, Lensch MW, Cahan P, Daley GQ. Investigating monogenic and complex diseases with pluripotent stem cells. Nat Rev Genet 2011;12:266-275. DOI ScienceOn |
68 | Miller JD, Ganat YM, Kishinevsky S, et al. Human iPSC-based modeling of late-onset disease via progerin- induced aging. Cell Stem Cell 2013;13:691-705. DOI ScienceOn |
69 | Wernig M, Zhao JP, Pruszak J, et al. Neurons derived from reprogrammed f ibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc Natl Acad Sci U S A 2008;105:5856-5861. DOI ScienceOn |
70 | Hanna J, Wernig M, Markoulaki S, et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 2007;318:1920-1923. DOI ScienceOn |
71 | Lui KO, Waldmann H, Fairchild PJ. Embryonic stem cells: overcoming the immunological barriers to cell replacement therapy. Curr Stem Cell Res Ther 2009;4:70-80. DOI ScienceOn |
72 | Takebe T, Sekine K, Enomura M, et al. Vascularized and functional human liver from an iPSC-derived organ bud transplant. Nature 2013;499:481-484. DOI ScienceOn |
73 | Kamao H, Mandai M, Okamoto S, et al. Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application. Stem Cell Reports 2014;2:205-218. DOI ScienceOn |
74 | Taylor CJ, Bolton EM, Bradley JA. Immunological considerations for embryonic and induced pluripotent stem cell banking. Philos Trans R Soc Lond B Biol Sci 2011;366:2312-2322. DOI |
75 | Zimmermann A, Preynat-Seauve O, Tiercy JM, Krause KH, Villard J. Haplotype-based banking of human pluripotent stem cells for transplantation: potential and limitations. Stem Cells Dev 2012;21:2364-2373. DOI ScienceOn |
76 | Taylor CJ, Peacock S, Chaudhry AN, Bradley JA, Bolton EM. Generating an iPSC bank for HLA-matched tissue transplantation based on known donor and recipient HLA types. Cell Stem Cell 2012;11:147-152. DOI ScienceOn |
77 | Lin G, Xie Y, Ouyang Q, et al. HLA-matching potential of an established human embryonic stem cell bank in China. Cell Stem Cell 2009;5:461-465. DOI ScienceOn |