A Combination of Melphalan, Prednisone, and 50 mg Thalidomide Treatment in Non-Transplant-Candidate Patients with Newly Diagnosed Multiple Myeloma |
Chang, Hye-Jung
(Department of Internal Medicine, Seoul National University Bundang Hospital)
Lee, Jae-Hoon (Department of Internal Medicine, Gachon University Gil Hospital) Do, Young-Rok (Department of Internal Medicine, Dongsan Medical Center, Keimyung University School of Medicine) Bae, Sung-Hwa (Department of Internal Medicine, Catholic University of Daegu) Lee, Jung-Lim (Department of Internal Medicine, Daegu Fatima Hospital) Nam, Seung-Hyun (Department of Internal Medicine, Seoul Veterans Hospital) , Sung-Soo (Department of Internal Medicine, Seoul National University Hospital) Bang, Soo-Mee (Department of Internal Medicine, Seoul National University Bundang Hospital) |
1 | Kyle R A, Rajkumar SV. Multiple myeloma. N Engl J Med 2004;351:1860-1873. DOI ScienceOn |
2 | Phekoo KJ, Schey SA, Richards MA, et al. A population study to define the incidence and survival of multiple myeloma in a National Health Service Region in UK. Br J Haematol 2004;127:299-304. DOI ScienceOn |
3 | Kim HJ, Heo DS, Bang YJ, et al. Multiple myeloma in Korea: clinical analysis and treatment results in 61 cases. Korean J Intern Med 1987;2:120-124. |
4 | Lee JH, Bang SM. Epidemiological change of multiple myeloma in Korea. Korean J Hematol 2006;41:225-234. DOI ScienceOn |
5 | Palumbo A, Bringhen S, Caravita T, et al. Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial. Lancet 2006;367:825-831. DOI ScienceOn |
6 | Hulin C, Facon T, Rodon P, et al. Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial. J Clin Oncol 2009;27:3664-3670. DOI ScienceOn |
7 | Wijermans P, Schaafsma M, Termorshuizen F, et al. Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: the HOVON 49 Study. J Clin Oncol 2010;28:3160-3166. DOI ScienceOn |
8 | Steurer M, Spizzo G, Mitterer M, Gastl G. Low-dose thalidomide for multiple myeloma: interim analysis of a compassionate use program. Onkologie 2004;27:150-154. DOI ScienceOn |
9 | Harousseau JL, Attal M, Avet-Loiseau H. The role of complete response in multiple myeloma. Blood 2009;114:3139-3146. DOI ScienceOn |
10 | El Accaoui RN, Shamseddeen WA, Taher AT. Thalidomide and thrombosis: a meta-analysis. Thromb Haemost 2007;97:1031-1036. |
11 | Koh Y, Bang SM, Lee JH, et al. Low incidence of clinically apparent thromboembolism in Korean patients with multiple myeloma treated with thalidomide. Ann Hematol 2010;89:201-206. DOI ScienceOn |
12 | San Miguel JF, Schlag R, Khuageva NK, et al. Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. N Engl J Med 2008;359:906-917. DOI ScienceOn |
13 | Zonder JA, Crowley J, Hussein MA, et al. Superiority of lenalidomide (Len) plus high-dose dexamethasone (HD) compared to HD alone as treatment of newly-diagnosed multiple myeloma (NDMM): results of the randomized, double-blinded, placebocontrolled SWOG trial S0232. Blood 2007;110:77. |
14 | Qazilbash MH, Saliba RM, Hosing C, et al. Autologous stem cell transplantation is safe and feasible in elderly patients with multiple myeloma. Bone Marrow Transplant 2007;39:279-283. DOI ScienceOn |
15 | Facon T, Mary JY, Hulin C, et al. Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced- intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial. Lancet 2007;370:1209-1218. DOI ScienceOn |
16 | Yakoub-Agha I, Attal M, Dumontet C, et al. Thalidomide in patients with advanced multiple myeloma: a study of 83 patients- -report of the Intergroupe Francophone du Myelome (IFM). Hematol J 2002;3:185-192. DOI ScienceOn |
17 | Attal M, Harousseau JL, Stoppa AM, et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma: intergroupe Francais du Myelome. N Engl J Med 1996;335:91-97. DOI ScienceOn |
18 | Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: an overview of 6,633 patients from 27 randomized trials. Myeloma Trialists' Collaborative Group. J Clin Oncol 1998;16:3832-3842. DOI |
19 | Waage A, Gimsing P, Fayers P, et al. Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma. Blood 2010;116:1405-1412. DOI ScienceOn |
20 | Singhal S, Mehta J, Desikan R, et al. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med 1999;341:1565-1571. DOI ScienceOn |
21 | Hus I, Dmoszynska A, Manko J, et al. An evaluation of factors predicting long-term response to thalidomide in 234 patients with relapsed or resistant multiple myeloma. Br J Cancer 2004;91:1873-1879. DOI ScienceOn |