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http://dx.doi.org/10.3904/kjm.2014.86.6.774

Hodgkin's Lymphoma after Autologous Hematopoietic Stem Cell Transplantation for Angioimmunoblastic T-cell Lymphoma  

Park, Su-Youn (Department of Internal Medicine, Konkuk University School of Medicine)
Yu, Hyung Min (Department of Internal Medicine, Konkuk University School of Medicine)
Kim, Jiwan (Department of Internal Medicine, Konkuk University School of Medicine)
An, Sang Hee (Department of Internal Medicine, Konkuk University School of Medicine)
Kim, Wook Youn (Department of Pathology, Konkuk University School of Medicine)
Hur, Mina (Department of Laboratory Medicine, Konkuk University School of Medicine)
Lee, Hong Gi (Department of Internal Medicine, Konkuk University School of Medicine)
Publication Information
The Korean Journal of Medicine / v.86, no.6, 2014 , pp. 774-780 More about this Journal
Abstract
Post-transplantation lymphoproliferative disorder (PTLD) is a serious complication that can develop after either solid organ or hematopoietic stem cell transplantation (HSCT). The incidence of Hodgkin's lymphoma (HL) ranges from 0.5-1.0% of PTLD after HSCT without T-cell depletion. Here, we report a case of HL-PTLD that occurred after autologous peripheral blood stem cell transplantation for an angioimmunoblastic T-cell lymphoma (AITL). A 36-year-old patient developed fever and chills with multiple lymphadenopathies at day 673 after auto-HSCT for AITL. Three months after the transplant, the patient developed fever with elevated plasma Epstein-Barr virus (EBV)-PCR values. The excisional biopsy revealed HL at Ann Arbor stage IIIB. A total of 8 cycles of chemotherapy with ABVD please define were performed, and the patient has remained disease-free. To our knowledge, this is first case report of HL-PTLD after auto-PBSCT in Korea.
Keywords
Lymphoproliferative disorder; Hodgkin disease; Hematopoietic stem cell transplantation; Epstein-Barr virus;
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Times Cited By KSCI : 3  (Citation Analysis)
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