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http://dx.doi.org/10.3904/kjm.2013.85.2.183

A Case of Large Cell Neuroendocrine Carcinoma of the Gallbladder  

Kim, Young Hoon (Department of Internal Medicine, Boramae Hospital, Seoul National University College of Medicine)
Jeong, Ji Bong (Department of Internal Medicine, Boramae Hospital, Seoul National University College of Medicine)
Joo, Sae Kyung (Department of Internal Medicine, Boramae Hospital, Seoul National University College of Medicine)
Choi, Min Young (Department of Internal Medicine, Boramae Hospital, Seoul National University College of Medicine)
Lee, Kook Lae (Department of Internal Medicine, Boramae Hospital, Seoul National University College of Medicine)
Chang, Mee Soo (Department of Pathology, Boramae Hospital, Seoul National University College of Medicine)
Ahn, Young Joon (Department of Surgery, Boramae Hospital, Seoul National University College of Medicine)
Publication Information
The Korean Journal of Medicine / v.85, no.2, 2013 , pp. 183-187 More about this Journal
Abstract
We herein report a case of large cell neuroendocrine carcinoma (NEC) of the gallbladder confirmed by laparoscopic surgery. A 60-year-old male was HBsAg-positive. Abdominal computed tomography showed a 2.5 ${\times}$ 2.5 cm enhancing polypoid mass in the gallbladder and multiple masses in liver segments 4 and 5 that enhanced in the arterial phase and washed out in the delayed phase. Liver biopsy findings showed only poorly differentiated morphology. A laparoscopic operation was performed for diagnosis of the masses because curative resection seemed impossible to perform, which showed unusual findings of either hepatocelluar carcinoma or gallbladder cancer. Therefore, laparoscopic liver biopsy and cholecystectomy were performed. The final pathologic results of the masses showed large cell NEC of the gallbladder with liver metastasis. Central bisegmentectomy and extensive lymph node dissection were ultimately performed. The patient was still alive 16 months after diagnosis.
Keywords
Carcinoma; Neuroendocrine; Gallbladder;
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