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http://dx.doi.org/10.3904/kjm.2013.84.5.704

Colonic Langerhans Cell Histiocytosis Presenting as an Isolated Polyp  

Seo, Hyun Woong (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine)
Han, Koon Hee (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine)
Kim, Sunghun (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine)
Hong, Man Yong (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine)
Yun, Jung Ho (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine)
Eom, Dae Woon (Department of Pathology, Gangneung Asan Hospital, University of Ulsan College of Medicine)
Cheon, Gab Jin (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine)
Publication Information
The Korean Journal of Medicine / v.84, no.5, 2013 , pp. 704-707 More about this Journal
Abstract
A 56-year-old male underwent a screening colonoscopy. An 8-mm sessile polyp was removed from the descending colon using snare polypectomy. Histology showed Langerhans cells and eosinophil infiltration of the submucosa. Immunohistochemical staining was positive for S-100 protein and CD1a antigen, which confirmed the diagnosis of Langerhans-cell histiocytosis. On further workup, there was no evidence of involvement of any other organs. Here, we report a very rare case of colonic Langerhans-cell histiocytosis presenting as an isolated polyp.
Keywords
Langerhans-cell histiocytosis; Colon; Polyps; S-100 protein; CD1a antigen;
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