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http://dx.doi.org/10.3904/kjm.2013.84.1.135

Four Cases of Metastasectomy for Pulmonary Metastasis of Nasopharyngeal Carcinoma  

Lee, Hyo Jung (Department of Hematology-Oncology, Ajou University School of Medicine)
Jeon, Ja Young (Department of Hematology-Oncology, Ajou University School of Medicine)
Han, Jae Ho (Department of Pathology, Ajou University School of Medicine)
Sun, Joo Sung (Department of Radiology, Ajou University School of Medicine)
Choi, Ho (Department of Thoracic Surgery Ajou University School of Medicine)
Choi, Jin-Hyuk (Department of Hematology-Oncology, Ajou University School of Medicine)
Ahn, Mi Sun (Department of Hematology-Oncology, Ajou University School of Medicine)
Publication Information
The Korean Journal of Medicine / v.84, no.1, 2013 , pp. 135-140 More about this Journal
Abstract
Nasopharyngeal carcinoma is a rare cancer with a relatively poor prognosis because patients tend to be diagnosed in the advanced stage. Distant metastases have been recognized to be a major cause of treatment failure. However, because long-term survival has been reported in patients with lung metastasis alone, an aggressive approach to treatment for this group of patients should be considered. We report four cases of metastasectomy for pulmonary metastasis of nasopharyngeal carcinoma. The metastatic lesions were confined to the lung with or without regional lymph nodes. The patients underwent a pulmonary metastasectomy following adjuvant chemotherapy with or without radiotherapy, and all patients are now disease-free.
Keywords
Nasopharyngeal neoplasm; Lung metastasis; Metastasectomy;
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1 Wei WI, Kwong DL. Current management strategy of nasopharyngeal carcinoma. Clin Exp Otorhinolaryngol 2010;3:1-12.   DOI   ScienceOn
2 Cho MJ, Jang JY, Kim JS, Kim BK, Song CJ, Kim JS. Results of radiation therapy in nasopharyngeal cancer. J Korean Soc Ther Radiol Oncol 2001;19:10-15.
3 Kim HS, Lee BJ, Kim SY. Clinical characteristics and treatment results of nasopharyngeal cancer. Korean J Otolaryngol 1998;41:251-256.
4 Hui EP, Leung SF, Au JS, et al. Lung metastasis alone in nasopharyngeal carcinoma: a relatively favorable prognostic group: a study by the Hong Kong Nasopharyngeal Carcinoma Study Group. Cancer 2004;101:300-306.   DOI   ScienceOn
5 Cao X, He LR, Xie FY, Chen YF, Wen ZS. Factors determining the survival of nasopharyngeal carcinoma with lung metastasis alone: does combined modality treatment benefit? BMC Cancer 2011;11:370-378.   DOI
6 Shiono S, Kawamura M, Sato T, et al. Pulmonary metastasectomy for pulmonary metastases of head and neck squamous cell carcinomas. Ann Thorac Surg 2009;88:856-860.   DOI   ScienceOn
7 Winter H, Meimarakis G, Hoffmann G, et al. Does surgical resection of pulmonary metastases of head and neck cancer improve survival? Ann Surg Oncol 2008;15:2915-2926.   DOI
8 Ma J, Wen ZS, Lin P, Wang X, Xie FY. The results and prognosis of different treatment modalities for solitary metastatic lung tumor from nasopharyngeal carcinoma: a retrospective study of 105 cases. Chin J Cancer 2010;29:787-795.   DOI
9 Ryoo HM. Management of pulmonary metastasis. Korean J Med 2011;81:289-299.
10 Suzuki S, Ishikawa K. Safety and efficacy of S-1 chemotherapy in recurrent/metastatic head and neck cancer. J Infect Chemother 2009;15:335-339.   DOI