Browse > Article
http://dx.doi.org/10.3904/kjm.2012.83.6.706

Role of Chemotherapy in Gastric Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue (MALT) Type  

Park, Yong (Division of Hematology/Oncology, Department of Internal Medicine, Korea University College of Medicine)
Publication Information
The Korean Journal of Medicine / v.83, no.6, 2012 , pp. 706-711 More about this Journal
Abstract
Gastric mucosa-associated lymphoid tissue (MALT) lymphoma comprises approximately 50% of primary gastric lymphoma. Currently, Helicobacter pyroli eradication is the mainstay in the management of localized gastric MALT lymphoma. However, other treatment strategies such as radiotherapy and chemotherapy should be required in certain circumstances which include H. pyroli-negative disease, H. pyroli-positive disease unresponsive to standard eradication, and advanced disease (stage III/IV). Here, we reviewed the role of chemotherapy in the management of patients with gastric MALT lymphoma based on recent clinical trials.
Keywords
Gastric MALT lymphoma; Chemotherapy; Marginal zone B cell lymphoma;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Neubauer A, Zucca E. Gastrointestinal tract lymphomas. In: Cavali F, Stein H, Zucca E, eds. Extranodal Lymphomas Pathology and Management. London: Informa Health Care, 2008:233-243.
2 Du MQ, Isaccson PG. Gastric MALT lymphoma: from aetiology to treatment. Lancet Oncol 2002;3:97-104.   DOI   ScienceOn
3 Zucca E, Bertoni F, Roggero E, Cavalli F. The gastric marginal zone B-cell lymphoma of MALT type. Blood 2000;96:410-419.
4 Fischbach W, Goebeler ME, Ruskone-Fourmestraux A, et al. Most patients with minimal histological residuals of gastric MALT lymphoma after successful eradication of Helicobacter pylori can be managed safely by a watch and wait strategy: experience from a large international series. Gut 2007;56:1685-1687.   DOI   ScienceOn
5 Stathis A, Chini C, Bertoni F, et al. Long-term outcome following Helicobacter pylori eradication in a retrospective study of 105 patients with localized gastric marginal zone B-cell lymphoma of MALT type. Ann Oncol 2009;20:1086-1093.   DOI   ScienceOn
6 Wundisch T, Thiede C, Morgner A, et al. Long-term follow-up of gastric MALT lymphoma after Helicobacter pylori eradication. J Clin Oncol 2005;23:8018-8024.   DOI   ScienceOn
7 Rohatiner A, d'Amore F, Coiffier B, et al. Report on a workshop convened to discuss the pathological and staging classifications of gastrointestinal tract lymphoma. Ann Oncol 1994;5:397-400.   DOI
8 Nakamura S, Yao T, Aoyagi K, Iida M, Fujishima M, Tsuneyoshi M. Helicobacter pylori and primary gastric lymphoma: a histopathologic and immunohistochemical analysis of 237 patients. Cancer 1997;79:3-11.   DOI   ScienceOn
9 Wotherspoon AC, Ortiz-Hidalgo C, Falzon MR, Isaacson PG. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 1991;338:1175-1176.   DOI   ScienceOn
10 Ruskone-Fourmestraux A, Fischbach W, Aleman BM, et al. EGILS consensus report: gastric extranodal marginal zone B-cell lymphoma of MALT. Gut 2011;60:747-758.   DOI   ScienceOn
11 National Comprehensive Cancer Network. National Comprehensive Cancer Network Guidelines V.3.2012-Non-Hodgkin's lymphomas [Internet]. Fort Washington (PA): National Comprehensive Cancer Network, c2012. Available from: http://www.nccn.org/index.asp.
12 Nakamura S, Matsumoto T, Ye H, et al. Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphoma: a clinicopathologic and molecular study with reference to antibiotic treatment. Cancer 2006;107:2770-2778.   DOI   ScienceOn
13 Ruskone-Fourmestraux A, Lavergne A, Aegerter PH, et al. Predictive factors for regression of gastric MALT lymphoma after anti-Helicobacter pylori treatment. Gut 2001;48:297-303.   DOI   ScienceOn
14 Steinbach G, Ford R, Glober G, et al. Antibiotic treatment of gastric lymphoma of mucosa-associated lymphoid tissue: an uncontrolled trial. Ann Intern Med 1999;131:88-95.   DOI   ScienceOn
15 Raderer M, Streubel B, Wohrer S, Hafner M, Chott A. Successful antibiotic treatment of Helicobacter pylori negative gastric mucosa associated lymphoid tissue lymphomas. Gut 2006;55:616-618.   DOI   ScienceOn
16 Martinelli G, Laszlo D, Ferreri AJ, et al. Clinical activity of rituximab in gastric marginal zone non-Hodgkin's lymphoma resistant to or not eligible for anti-Helicobacter pylori therapy. J Clin Oncol 2005;23:1979-1983.   DOI   ScienceOn
17 Hammel P, Haioun C, Chaumette MT, et al. Efficacy of single-agent chemotherapy in low-grade B-cell mucosaassociated lymphoid tissue lymphoma with prominent gastric expression. J Clin Oncol 1995;13:2524-2529.   DOI
18 Levy M, Copie-Bergman C, Gameiro C, et al. Prognostic value of translocation t(11;18) in tumoral response of low-grade gastric lymphoma of mucosa-associated lymphoid tissue type to oral chemotherapy. J Clin Oncol 2005;23:5061-5066.   DOI   ScienceOn
19 Hussell T, Isaacson PG, Crabtree JE, Spencer J. Helicobacter pylori-specific tumour-infiltrating T cells provide contact dependent help for the growth of malignant B cells in low-grade gastric lymphoma of mucosa-associated lymphoid tissue. J Pathol 1996;178:122-127.   DOI   ScienceOn
20 Hancock BW, Qian W, Linch D, et al. Chlorambucil versus observation after anti-Helicobacter therapy in gastric MALT lymphomas: results of the international randomised LY03 trial. Br J Haematol 2009;144:367-375.   DOI   ScienceOn
21 Hussell T, Isaacson PG, Spencer J. Proliferation and differentiation of tumour cells from B-cell lymphoma of mucosa-associated lymphoid tissue in vitro. J Pathol 1993;169:221-227.   DOI
22 Jager G, Neumeister P, Brezinschek R, et al. Treatment of extranodal marginal zone B-cell lymphoma of mucosaassociated lymphoid tissue type with cladribine: a phase II study. J Clin Oncol 2002;20:3872-3877.   DOI   ScienceOn
23 Jager G, Neumeister P, Quehenberger F, Wohrer S, Linkesch W, Raderer M. Prolonged clinical remission in patients with extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type treated with cladribine: 6 year follow-up of a phase II trial. Ann Oncol 2006;17:1722-1723.   DOI   ScienceOn
24 Wohrer S, Raderer M, Kaufmann H, et al. Effective treatment of indolent non-hodgkin's lymphomas with mitoxantrone, chlorambucil and prednisone. Onkologie 2005;28:73-78.   DOI   ScienceOn
25 Raderer M, Wohrer S, Streubel B, et al. Activity of rituximab plus cyclophosphamide, doxorubicin/mitoxantrone, vincristine and prednisone in patients with relapsed MALT lymphoma. Oncology 2006;70:411-417.   DOI   ScienceOn
26 Levy M, Copie-Bergman C, Molinier-Frenkel V, et al. Treatment of t(11;18)-positive gastric mucosa-associated lymphoid tissue lymphoma with rituximab and chlorambucil: clinical, histological, and molecular follow-up. Leuk Lymphoma 2010;51:284-290.   DOI   ScienceOn
27 Salar A, Domingo-Domenech E, Estany C, et al. Combination therapy with rituximab and intravenous or oral fludarabine in the first-line, systemic treatment of patients with extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type. Cancer 2009;115:5210-5217.   DOI   ScienceOn
28 Isaacson PG, Du MQ. MALT lymphoma: from morphology to molecules. Nat Rev Cancer 2004;4:644-653.   DOI   ScienceOn
29 Kang HJ, Kim WS, Kim SJ, et al. Phase II trial of rituximab plus CVP combination chemotherapy for advanced stage marginal zone lymphoma as a first-line therapy: Consortium for Improving Survival of Lymphoma (CISL) Study. Ann Hematol 2012;91:543-551.   DOI   ScienceOn
30 Farinha P, Gascoyne RD. Molecular pathogenesis of mucosa-associated lymphoid tissue lymphoma. J Clin Oncol 2005;23:6370-6378.   DOI   ScienceOn
31 Troch M, Jonak C, Mullauer L, et al. A phase II study of bortezomib in patients with MALT lymphoma. Haematologica 2009;94:738-742.   DOI   ScienceOn
32 Stathis A, Bertoni F, Zucca E. Treatment of gastric marginal zone lymphoma of MALT type. Expert Opin Pharmacother 2010;11:2141-2152.   DOI   ScienceOn