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http://dx.doi.org/10.3904/kjm.2012.83.4.525

A Case of Cardiogenic Shock after Chemotherapy with 5-Fluorouracil and Leucovorin in Rectal Cancer  

Yoon, Jee-Hee (Department of Internal Medicine, Chonnam National Universtiy Medical School)
Kim, Dong-Hyun (Department of Internal Medicine, Chonnam National Universtiy Medical School)
Kim, Seung-Hun (Department of Internal Medicine, Chonnam National Universtiy Medical School)
Choi, Won-Young (Department of Internal Medicine, Chonnam National Universtiy Medical School)
Koh, Young-Il (Department of Internal Medicine, Chonnam National Universtiy Medical School)
Chung, Ik-Joo (Department of Internal Medicine, Chonnam National Universtiy Medical School)
Bae, Woo-Kyun (Department of Internal Medicine, Chonnam National Universtiy Medical School)
Publication Information
The Korean Journal of Medicine / v.83, no.4, 2012 , pp. 525-528 More about this Journal
Abstract
A 51-year-old man with rectal adenocarcinoma was admitted to hospital for neoadjuvant concurrent chemoradiotherapy. Three days after receiving 5-fluorouracil (425 mg/$m^2$) and leucovorin (20 mg/$m^2$) chemotherapy, the patient complained of chest pain. The patient had no history of cardiac disease. Electrocardiography showed ST segment elevation in leads II, III, and aVF, but the cardiac enzymes were normal. Transthoracic echocardiography revealed global hypokinesia with marked systolic dysfunction (ejection fraction 21.55%) and coronary angiography showed no significant stenosis. Unfortunately, he died of cardiogenic shock, despite intensive medical treatment.
Keywords
5-Fluorouracil(5-FU); Cardiogenic shock; Rectal cancer;
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