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http://dx.doi.org/10.3904/kjm.2012.83.3.385

A Case of Primary Effusion Lymphoma in a Patient with Chronic Kidney Disease  

Kim, Mi-Yeon (Department of Internal Medicine, Jeju National University School of Medicine)
Han, Sang-Hoon (Department of Internal Medicine, Jeju National University School of Medicine)
Yu, Jung-Re (Department of Internal Medicine, Jeju National University School of Medicine)
Jeong, Woo-Seong (Department of Internal Medicine, Jeju National University School of Medicine)
Kim, Hyun-Woo (Department of Internal Medicine, Jeju National University School of Medicine)
Lee, Jae-Chun (Department of Internal Medicine, Jeju National University School of Medicine)
Hyun, Chang-Lim (Department of Pathology, Jeju National University School of Medicine)
Publication Information
The Korean Journal of Medicine / v.83, no.3, 2012 , pp. 385-389 More about this Journal
Abstract
Human herpes virus-8 (HHV-8)-negative primary effusion lymphoma (PEL) is frequently observed in patients with chronic liver disease. We describe herein a case of PEL in a patient with chronic kidney disease. A 59-year-old woman presented with dyspnea. The patient had a history of uncontrolled pleural effusion. The pleural effusion revealed a malignant cell-dominant exudate. Serological tests were negative for human immunodeficiency virus (HIV). Initial chest and abdomen computed tomography showed bilateral pleural effusion; however, no evidence of a tumor mass or lymph node enlargement was found. A malignant lymphoma of diffuse large B-cell type was confirmed by pleural fluid cytology. Immunohistochemical staining of malignant cells was negative for HHV-8. She was treated with rituximab and CHOP (cyclophosphamide, adriamycin, vincristine, prednisolone) chemotherapy. We report a case of PEL in a patient with chronic kidney disease that may be a plausible predisposing factor for HHV-8-negative PEL.
Keywords
Chemotherapy; Diffuse large B cell lymphoma; Primary effusion lymphoma;
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