Browse > Article
http://dx.doi.org/10.3904/kjm.2012.83.3.342

A Case of Idiopathic Eosinophilic Cholecystitis Treated with Steroids  

Kang, Hyun-Jun (Department of Internal Medicine, Kwak's Hospital)
Choi, Min-Ho (Department of Internal Medicine, Kwak's Hospital)
Kim, Ho-Tae (Department of Internal Medicine, Kwak's Hospital)
Kwak, Tae-Yeong (Department of Internal Medicine, Kwak's Hospital)
Lee, Hyun-Chaol (Department of Internal Medicine, Kwak's Hospital)
Kim, Yeong-Sung (Department of Internal Medicine, Kwak's Hospital)
Kwak, Dong-Hyup (Department of Internal Medicine, Kwak's Hospital)
Publication Information
The Korean Journal of Medicine / v.83, no.3, 2012 , pp. 342-346 More about this Journal
Abstract
Eosinophilic cholecystitis is a rare disease characterized by transmural leukocyte infiltration composed of more than 90% eosinophils. Eosinophilic cholecystitis is clinically indistinguishable from ordinary cholecystitis, and as a rule it leads to cholecystectomy. We report a case of idiopathic eosinophilic cholecystitis treated with steroids. A 75-year-old woman presented with a classic history of acute cholecystitis and a peripheral eosinophilia of 41.8%. There was no evidence of allergy or parasitic infestation. An abdominal ultrasonography and computed tomography (CT) scan showed an edematous, thickened gallbladder wall, but no gallstones. There was no evidence of eosinophilic infiltration in other organs. Cholecystectomy was not performed because the patient refused surgical management. However, fever, abdominal pain, and peripheral eosinophilia persisted despite antibiotic and conservative therapy. Therefore, we attempted treatment with prednisolone. A week later, the symptoms disappeared and the peripheral eosinophilia normalized.
Keywords
Eosinophilic cholecystitis; Idiopathic; Steroids;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Dabbs DJ. Eosinophilic and lymphoeosinophilic cholecystitis. Am J Surg Pathol 1993;17:497-501.   DOI   ScienceOn
2 Vauthey JN, Loyer E, Chokshi P, Lahoti S. Case 57: eosinophilic cholangiopathy. Radiology 2003;227:107-112.   DOI   ScienceOn
3 Kim ES, Lyu ST, Lee MH, et al. A case of eosinophilic cholecystitis with hepatitis associated with clonorchiasis: case reports. Korean J Med 2003;65(Suppl 3):S912-S916.
4 Lee JY, Hwang ET, Yeom DH, et al. A case of eosinophilic cholecystitis associated with gallstones. Korean J Med 2009;76:467-470.
5 Felman RH, Sutherland DB, Conklin JL, Mitros FA. Eosinophilic cholecystitis, appendiceal inflammation, pericarditis, and cephalosporin-associated eosinophilia. Dig Dis Sci 1994;39:418-422.   DOI   ScienceOn
6 Tajima K, Katagiri T. Deposits of eosinophil granule proteins in eosinophilic cholecystitis and eosinophilic colitis associated with hypereosinophilic syndrome. Dig Dis Sci 1996;41: 282-288.   DOI   ScienceOn
7 Fauci AS, Harley JB, Roberts WC, Ferrans VJ, Gralnick HR, Bjornson BH. NIH conference: the idiopathic hypereosinophilic syndrome: clinical, pathophysiologic, and therapeutic considerations. Ann Intern Med 1982;97:78-92.   DOI   ScienceOn
8 Khan S, Orenstein SR. Eosinophilic disorders of the gastrointestinal tract. In: Feldman M, Friedman LS, Brandt LJ. Sleisenger and Fordtrans's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia: Saunders Elsevier, 2010:428-430.
9 Butler TW, Feintuch TA, Caine WP Jr. Eosinophilic cholangitis, lymphadenopathy, and peripheral eosinophilia: a case report. Am J Gastroenterol 1985;80:572-574.