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http://dx.doi.org/10.3904/kjm.2012.82.5.532

Management of Chemotherapy Induced Nausea and Vomiting  

Song, Kyung-Ho (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Konyang University Hospital)
Publication Information
The Korean Journal of Medicine / v.82, no.5, 2012 , pp. 532-536 More about this Journal
Abstract
Chemotherapy induced nausea and vomiting (CINV) is typically biphasic. The acute phase usually peaks in 5-6 hours after the administration of chemotherapeutic agents and the delayed phase can occur subsequently over 24hours after chemotherapy. Antiemetic therapy is crucial to prevent this unwanted side effect effectively, and NK1 antagonist, $5-HT_{3}$ antagonist, corticosteroid are the main player. The combination and dosing is determined by the emetogenicity of the chemotherapeutic agents to be administrated.
Keywords
Antiemetics; Chemotherapy;
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