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http://dx.doi.org/10.3904/kjm.2012.82.3.386

A Refractory Case of Granulomatous Mastitis Treated with Methotrexate  

Yoo, Jong-Jin (Department of Internal Medicine, Seoul National University Bundang Hospital)
Kang, Eun-Ha (Department of Internal Medicine, Seoul National University Bundang Hospital)
Lee, Yun-Jong (Department of Internal Medicine, Seoul National University Bundang Hospital)
Kim, Sung-Won (Department of Surgery, Seoul National University College of Medicine)
Choi, In-Ah (Department of Internal Medicine, Seoul National University College of Medicine)
Lee, Eun-Bone (Department of Internal Medicine, Seoul National University College of Medicine)
Song, Yeong-Wook (Department of Internal Medicine, Seoul National University College of Medicine)
Publication Information
The Korean Journal of Medicine / v.82, no.3, 2012 , pp. 386-391 More about this Journal
Abstract
Granulomatous mastitis (GM) is an uncommon chronic inflammatory disease of the breast that can mimic breast carcinoma or infection. The treatment options include expectant management, complete resection, and corticosteroid therapy, although no standard treatment has been established. Recently, several case reports have suggested that methotrexate is another effective treatment for GM. Here, we describe the first Korean case of recurrent GM successfully treated with low-dose weekly methotrexate and review the relevant literature.
Keywords
Granulomatous mastitis; Methotrexate;
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