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http://dx.doi.org/10.3904/kjm.2012.82.1.110

Quadruple Mtachronous Primary Neoplasms in the Aerodigestive Tract  

Kim, Yong-Hyun (Department of Internal Medicine, Dankook University College of Medicine)
Park, Keon-Woo (Department of Internal Medicine, Dankook University College of Medicine)
Lee, Soon-Il (Department of Internal Medicine, Dankook University College of Medicine)
Lim, Do-Hyoung (Department of Internal Medicine, Dankook University College of Medicine)
Lee, Hyun-Suk (Department of Internal Medicine, Dankook University College of Medicine)
Hyun, Kyung-Hee (Department of Internal Medicine, Dankook University College of Medicine)
Publication Information
The Korean Journal of Medicine / v.82, no.1, 2012 , pp. 110-114 More about this Journal
Abstract
Multiple primary neoplasms, defined as the occurrence of multiple malignant neoplasms in the same individual, were first reported by Billroth in 1889. With gradual improvements in diagnostics, and the early detection and effective treatment of malignant neoplasms, the prevalence of multiple primary neoplasms seems to be increasing. Although there have been several reports of triple primary neoplasms in Korea, cases of quadruple neoplasms are rare. Recently, we diagnosed a 69-year-old male with primary neoplasms in the lung, esophagus, vocal cords, and hypopharynx. The authors report this rare case of four metachronous primary neoplasms and provide a review of the literature.
Keywords
Multiple primary neoplasms; Aerodigestive tract;
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