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Intravesical Cidofovir in the Treatment of Hemorrhagic Cystitis after Unrelated Cord Blood Transplantation  

Yoon, Harry (Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine)
Kim, Jo-Eun (Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine)
Park, Ji-Soo (Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine)
Lee, Jeong-Guil (Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine)
Shin, Dae-Kyu (Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine)
Oh, Do-Yeun (Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine)
Chong, So-Young (Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine)
Publication Information
The Korean Journal of Medicine / v.81, no.5, 2011 , pp. 663-666 More about this Journal
Abstract
Hemorrhagic cystitis is a common complication in hematopoietic stem cell transplant recipients. We report a case of hemorrhagic cystitis after unrelated cord blood transplantation associated with adenovirus infection. Despite hydration, hematuria and large clots persisted. We instilled cidofovir into the bladder, which resulted in clearance of the adenovirus and significant clinical improvement. Our case emphasizes the effectiveness of intravesical cidofovir treatment for viral hemorrhagic cystitis.
Keywords
Adenovirus; Cystitis; Cidofovir; Cord blood stem cell transplantation;
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