Browse > Article

Clinical Manifestations and Diagnosis of Gout  

Lee, Eun-Bong (Department of Internal Medicine, Seoul National University College of Medicine)
Publication Information
The Korean Journal of Medicine / v.80, no.3, 2011 , pp. 255-259 More about this Journal
Abstract
Gout is one of the most common inflammatory arthritidies in men and postmenopausal women. It causes recurrent and severe pain in the affected joints, especially in the first metatarsophalangeal joint. The stages of gout are divided into asymptomatic hyperuricemia, acute intermittent arthritis with intercritical period and chronic tophaceous gout. It also affects kidney and causes nephrolithiasis and urate nephropathy. Gout can be diagnosed by confirming monosodium urate crystals in the joint fluid through polarizing microscope. In some cases, clinical diagnosis can be made based on the typical features of the attacks. Differential diagnosis from infectious arthritis is important.
Keywords
Gout; Clinical manifestation; Diagnosis;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Becker MA, Jolly M. Hyperuricemia and associated diseases. Rheum Dis Clin North Am 2006;32:275-293.   DOI   ScienceOn
2 Schlesinger N. Diagnosing and treating gout: a review to aid primary care physicians. Postgrad Med 2010;122:157-161.   DOI   ScienceOn
3 Gutman AB. Gout and gouty arthritis. In: Beeson PB, McDermott W, eds. Textbook of Medicine. 12th ed. Philadelphia: Saunders, 1958:595.
4 Grundy SM, Hansen B, Smith Sc Jr, Cleeman JI. Clinical management of metabolic syndrome: report of the American heart association national heart, lung, and blood institute American diabetes association conference on scientific issues related to management. Circulation 2004;109:551-556.   DOI   ScienceOn
5 Vazquez-Mellado J, Garcia CG, Vazquez SG, et al. Metabolic syndrome and ischemic heart disease in gout. J Clin Rheumatol 2004;10:105-109.   DOI   ScienceOn
6 Kahn HA, Medalie JH, Neufeld HN, Riss E, Goldbourt U. The incidence of hypertension and associated factors: the Israel ischemic heart disease study. Am Heart J 1972;84:171-182.   DOI   ScienceOn
7 Ward HJ. Uric acid as an independent risk factor in the treatment of hypertension. Lancet 1998;352:670-671.   DOI   ScienceOn
8 Tomita M, Mizuno S, Yamanaka H, et al. Does hyperuricemia affect mortality? A prospective cohort study of Japanese male workers. J Epidemiol 2000;10:403-409.   DOI   ScienceOn
9 Burack DA, Griffith BP, Thompson ME, Kahl LE. Hyperuricemia and gout among heart transplant recipients receiving cyclosporine. Am J Med 1992;92:141-146.   DOI   ScienceOn
10 Puig JG, Michan AD, Jimenez ML, et al. Female gout: clinical spectrum and uric acid metabolism. Arch Intern Med 1991; 151:726-732.   DOI   ScienceOn
11 Howe S, Edwards NL. Controlling hyperuricemia and gut in cardiac transplant recipients. J Musculoskel Med 1995;12:15-24.
12 Beck LH. Requiem for gouty nephropathy. Kidney Int 1986;30: 280-287. 13. Logan JA, Morrison E, McGill PE. Serum uric acid in acute gout. Ann Rheum Dis 1997;56:696-697.
13 Logan JA, Morrison E, McGill PE. Serum uric acid in acute gout. Ann Rheum Dis 1997;56:696-697.
14 Wallace SL, Robinson H, Masi AT, Decker JL, McCarty DJ, Yu TF. Preliminary criteria for the classification of the acute arthritis of primary gout. Arthritis Rheum 1977;20:895-900.   DOI   ScienceOn
15 Edwards NL. Clinical gout. In: Hochberg MC, Silman AJ, Solen JS, Weinblat ME, Weisman MH, eds. Rheumatology. 5th ed. Philadelphia: Elsevier, 2011:1859-1865.