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A case of sideroblastic anemia caused by lead-containing herbal medication  

Park, Hyun-Sik (Department of Internal Medicine, KonKuk University School of Medicine)
Kim, Sung-Young (Department of Internal Medicine, KonKuk University School of Medicine)
Cho, Jin-Hee (Department of Laboratory Medicine, KonKuk University School of Medicine)
Moon, Hee-Won (Department of Laboratory Medicine, KonKuk University School of Medicine)
Yoon, So-Young (Department of Internal Medicine, KonKuk University School of Medicine)
Cho, Yo-Han (Department of Internal Medicine, KonKuk University School of Medicine)
Lee, Mark Hong (Department of Internal Medicine, KonKuk University School of Medicine)
Publication Information
The Korean Journal of Medicine / v.79, no.4, 2010 , pp. 448-452 More about this Journal
Abstract
Although lead intoxication is commonly mentioned as a cause of sideroblastic anemia, no well-documented case exists in the literature. We encountered a patient with sideroblastic anemia caused by lead-containing herbal medicine. A 34-year-old woman was admitted to our hospital with abdominal pain. She had taken herbal medicine for her general health. Anemia, hyperbilirubinemia, and elevated lactic dehydrogenase were found from the laboratory data. Bone marrow biopsy showed pathological ringed sideroblasts. Her serum level of lead was high and the lead content of the tablet was higher than permitted. We diagnosed her with sideroblastic anemia secondary to lead poisoning caused by herbal medicine. We stopped her from taking herbal medicine and she gradually recovered from anemia.
Keywords
Sideroblastic anemia; Lead; Herbal medicine;
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Times Cited By KSCI : 1  (Citation Analysis)
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1 Fischbein A, Hu H. Occupational and environmental exposure to lead. In: Rom WN, Markowitz SB, eds. Environmental and occupational medicine. 4th ed. p. 958, Philadelphia, Wolters Kluwer/ Lippincott Williams & Wilkins, 2007
2 Pagliuca A, Mufti GJ, Baldwin D, Lestas AN, Wallis RM, Bellingham AJ. Lead poisoning: clinical, biochemical, and haematological aspects of a recent outbreak. J Clin Pathol 43: 277-281, 1990   DOI
3 Kim JY, Kim JH, Kim HW, Roh JH, Lee KH, Cheon BC, Nam SM. A review of lead poisoning cases reported for recent 30 years in Korea. Korean J Med 66:617-624, 2004
4 Oh SW. The study on heavy metal contamination of traditional drugs (Herbpills). p. 6-40, Research Laboratory, Korean Medical Association, 1983
5 대한혈액학회. 혈액학. 초판. p. 85, 서울, 이퍼블릭, 2006
6 Alcindor T, Bridges KR. Sideroblastic anemias. British Journal of Haematology 116:733-743, 2002   DOI   ScienceOn
7 Koh SH, Cho MG, Yoon DY, Park YS, Jung KS, Park KC, Ryu JS, Cho HC. Case of isoniazid-induced sideroblastic anemia. Korean J Med 42:699-702, 1992
8 Dacie JV, Doniach I. The basophilic property of the iron-containing granules in siderocytes. J Pathol Bacteriol 59:684-686, 1947   DOI
9 Rundles RW, Falls HF. Hereditary (sex-linked) anemia. Am J Med Sci 211:641-658, 1946   DOI
10 McFadzean AJ, Davis LJ. Iron staining erythrocyte inclusions with special reference to acquired haemolytic anemia. Glsgow Med J 28:237-279, 1947
11 Forman WB, Sheehan D, Cappelli S, Coffman B. Zinc abuse: an unsuspected cause of sideroblastic anemia. West J Med 152: 190-192, 1990