Salmonella Promotes ASC Oligomerization-dependent Caspase-1 Activation |
Hwang, Inhwa
(Department of Microbiology and Immunology, Yonsei University College of Medicine)
Park, Sangjun (Department of Microbiology and Immunology, Yonsei University College of Medicine) Hong, Sujeong (Department of Microbiology and Immunology, Yonsei University College of Medicine) Kim, Eun-Hee (Department of Microbiology and Immunology, Yonsei University College of Medicine) Yu, Je-Wook (Department of Microbiology and Immunology, Yonsei University College of Medicine) |
1 | Fernandes-Alnemri, T., J. Wu, J. W. Yu, P. Datta, B. Miller, W. Jankowski, S. Rosenberg, J. Zhang, and E. S. Alnemri. 2007. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 14: 1590-1604. DOI |
2 | Strowig, T., J. Henao-Mejia, E. Elinav, and R. Flavell. 2012. Inflammasomes in health and disease. Nature 481: 278-286. DOI |
3 | Hong, S., S. Park, and J. W. Yu. 2011. Pyrin domain (PYD)- containing inflammasome in innate immunity. J. Bacteriol. Virol. 41: 133-146. DOI |
4 | Fernandes-Alnemri, T., J. W. Yu, P. Datta, J. Wu, and E. S. Alnemri. 2009. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458: 509-513. DOI |
5 | Elinav, E., T. Strowig, J. Henao-Mejia, and R. A. Flavell. 2011. Regulation of the antimicrobial response by NLR proteins. Immunity 34: 665-679. DOI |
6 | Franchi, L., R. Muñoz-Planillo, and G. Núñez. 2012. Sensing and reacting to microbes through the inflammasomes. Nat. Immunol. 13: 325-332. DOI |
7 | Miao, E. A., C. M. Alpuche-Aranda, M. Dors, A. E. Clark, M. W. Bader, S. I. Miller, and A. Aderem. 2006. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat. Immunol. 7: 569-575. DOI |
8 | Franchi, L., A. Amer, M. Body-Malapel, T. D. Kanneganti, N. Ozören, R. Jagirdar, N. Inohara, P. Vandenabeele, J. Bertin, A. Coyle, E. P. Grant, and G. Núñez. 2006. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat. Immunol. 7: 576-582. DOI |
9 | Miao, E. A., D. P. Mao, N. Yudkovsky, R. Bonneau, C. G. Lorang, S. E. Warren, I. A. Leaf, and A. Aderem. 2010. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc. Natl. Acad. Sci. U.S.A. 107:3076-3080. DOI |
10 | Kofoed, E. M. and R. E. Vance. 2011. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477: 592-595. DOI |
11 | Zhao, Y., J. Yang, J. Shi, Y. N. Gong, Q. Lu, H. Xu, L. Liu, and F. Shao. 2011. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477: 596-600. DOI |
12 | Fernandes-Alnemri, T., J. W. Yu, C. Juliana, L. Solorzano, S. Kang, J. Wu, P. Datta, M. McCormick, L. Huang, E. McDermott, L. Eisenlohr, C. P. Landel, and E. S. Alnemri. 2010. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat. Immunol. 11: 385-393. |
13 | Poyet, J. L., S. M. Srinivasula, M. Tnani, M. Razmara, T. Fernandes-Alnemri, and E. S. Alnemri. 2001. Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J. Biol. Chem. 276: 28309-28313. DOI |
14 | Mariathasan, S., K. Newton, D. M. Monack, D. Vucic, D. M. French, W. P. Lee, M. Roose-Girma, S. Erickson, and V. M. Dixit. 2004. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430: 213-218. DOI |
15 | Mariathasan, S., D. S. Weiss, K. Newton, J. McBride, K. O'Rourke, M. Roose-Girma, W. P. Lee, Y. Weinrauch, D. M. Monack, and V. M. Dixit. 2006. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440: 228-232 DOI |
16 | Broz. P., J. von Moltke, J. W. Jones, R. E. Vance, and D. M. Monack. 2010. Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host Microbe 8: 471-483. DOI |
17 | Eisenbarth, S. C., O. R. Colegio, W. O'Connor, F. S. Sutterwala, and R. A. Flavell. 2008. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453: 1122-1126. DOI |
18 | Hornung, V., F. Bauernfeind, A. Halle, E. O. Samstad, H. Kono, K. L. Rock, K. A. Fitzgerald, and E. Latz. 2008. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol. 9: 847-856. DOI |
19 | Yu, J. W., T. Fernandes-Alnemri, P. Datta, J. Wu, C. Juliana, L. Solorzano, M. McCormick, Z. Zhang, and E. S. Alnemri. 2007. Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants. Mol. Cell 28: 214-227. DOI |
20 | Pétrilli, V., S. Papin, C. Dostert, A. Mayor, F. Martinon, and J. Tschopp. 2007. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 14: 1583-1589. DOI |
21 | Broz, P., K. Newton, M. Lamkanfi, S. Mariathasan, V. M. Dixit, and D. M. Monack. 2010. Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J. Exp. Med. 207: 1745-1755. DOI |
22 | Franchi, L., T. D. Kanneganti, G. R. Dubyak, and G. Núñez. 2007. Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria. J. Biol. Chem. 282: 18810-18818. DOI |
23 | Arlehamn, C. S., V. Pétrilli, O. Gross, J. Tschopp, and T. J. Evans. 2010. The role of potassium in inflammasome activation by bacteria. J. Biol. Chem. 285: 10508-10518. DOI |
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