Apoptosis of Human Islet Cells by Cytokines |
Kim, Sun-Shin
(New Experimental Therapeutics Branch, Division of Convergence Technology, National Cancer Center)
Kim, Kyoung-Ah (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) Suk, Kyoung-Ho (Department of Pharmacology, Brain Science and Engineering Institute, CMRI, Kyungpook National University School of Medicine) Kim, Yun-Hee (Molecular Imaging & Therapy Branch, Division of Convergence Technology, National Cancer Center) Oh, Seung-Hoon (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) Lee, Moon-Kyu (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) Kim, Kwang-Won (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) Lee, Myung-Shik (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) |
1 | Kim, S., H. S. Kim, K. W. Chung, S. H. Oh, J. W. Yun, S. H. Im, M. K. Lee, K. W. Kim, and M. S. Lee. 2007. Essential role for signal transducer and activator of transcription- 1 in pancreatic beta-cell death and autoimmune type 1 diabetes of nonobese diabetic mice. Diabetes 56: 2561-2568. DOI ScienceOn |
2 | Suk, K., S. Kim, Y. H. Kim, K. A. Kim, I. Chang, H. Yagita, M. Shong, and M. S. Lee. 2001. IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death. J. Immunol. 166: 4481-4489. DOI |
3 | Kim, H. S., M. S. Han, K. W. Chung, S. Kim, E. Kim, M. J. Kim, E. Jang, H. A. Lee, J. Youn, S. Akira, and M. S. Lee. 2007. TLR2 as a link between β-cell injury and initiation of autoimmune diabetes. Immunity 27: 321-333. DOI ScienceOn |
4 | Turley, S., L. Poirot, M. Hattori, C. Benoist, and D. Mathis. 2003. Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model. J. Exp. Med. 198: 1527-1537. DOI ScienceOn |
5 | Wicker, L. S., B. J. Miller, and Y. Mullen. 1986. Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice. Diabetes 35: 855-860. DOI ScienceOn |
6 | Wang, Y., O. Pontesilli, R. G. Gill, F. G. La Rosa, and K. J. Lafferty. 1991. The role of CD4+ and CD8+ T cells in the destruction of islet grafts by spontaneously diabetic mice. Proc. Natl. Acad. Sci. U. S. A. 88: 527-531. DOI ScienceOn |
7 | Katz, J. D., C. Benoist, and D. Mathis. 1995. T helper cell subsets in insulin-dependent diabetes. Science 268: 1185- 1188. DOI |
8 | Kurrer, M. O., S. V. Pakala, H. L. Hanson, and J. D. Katz. 1997. Beta cell apoptosis in T cell-mediated autoimmune diabetes. Proc. Natl. Acad. Sci. U. S. A. 94: 213-218. DOI ScienceOn |
9 | Kim, Y. H., S. Kim, K. A. Kim, H. Yagita, N. Kayagaki, K. W. Kim, and M. S. Lee. 1999. Apoptosis of pancreatic beta- cells detected in accelerated diabetes of NOD mice: no role of Fas-Fas ligand interaction in autoimmune diabetes. Eur. J. Immunol. 29: 455-465. DOI ScienceOn |
10 | Amrani, A., J. Verdaguer, B. Anderson, T. Utsugi, S. Bou, and P. Santamaria. 1999. Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice. J. Clin. Invest. 103: 1201-1209. DOI ScienceOn |
11 | Kim, S., K. A. Kim, D. Y. Hwang, T. H. Lee, N. Kayagaki, H. Yagita, and M. S. Lee. 2000. Inhibition of autoimmune diabetes by Fas ligand: the paradox is solved. J. Immunol. 164: 2931-2936. DOI |
12 | Ricordi, C., P. E. Lacy, E. H. Finke, B. J. Olack, and D. W. Scharp. 1988. Automated method for isolation of human pancreatic islets. Diabetes 37: 413-420. DOI ScienceOn |
13 | Rabinovitch, A., W. Sumoski, R. V. Rajotte, and G. L. Warnock. 1990. Cytotoxic effects of cytokines on human pancreatic islet cells in monolayer culture. J. Clin. Endocrinol. Metab. 71: 152-156. DOI |
14 | Rabinovitch, A., W. L. Suarez-Pinzon, K. Strynadka, R. Schulz, J. R. Lakey, G. L. Warnock, and R. V. Rajotte. 1994. Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production. J. Clin. Endocrinol. Metab. 79: 1058-1062. DOI |
15 | Delaney, C. A., D. Pavlovic, A. Hoorens, D. G. Pipeleers, D. L. Eizirik. 1997. Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells. Endocrinology 138: 2610-2614. DOI ScienceOn |
16 | Marselli, L., F. Dotta, S. Piro, C. Santangelo, M. Masini, R. Lupi, M. Realacci, S. del Guerra, F. Mosca, U. Boggi, F. Purrello, R. Navalesi, and P. Marchetti. 2001. Th2 cytokines have a partial, direct protective effect on the function and survival of isolated human islets exposed to combined proinflammatory and Th1 cytokines. J. Clin. Endocrinol. Metab. 86: 4974-4978. DOI ScienceOn |
17 | Suk, K., I. Chang, Y. H. Kim, S. Kim, J. Y. Kim, H. Kim, and M. S. Lee. 2001. Interferon gamma (IFNgamma) and tumor necrosis factor alpha synergism in ME-180 cervical cancer cell apoptosis and necrosis. IFNgamma inhibits cytoprotective NF-kappa B through STAT1/IRF-1 pathways. J. Biol. Chem. 276: 13153-13159. DOI ScienceOn |
18 | Barthson, J., C. M. Germano, F. Moore, A. Maida, D. J. Drucker, P. Marchetti, C. Gysemans, C. Mathieu, G. Nunez, A. Jurisicova, D. L. Eizirik, and E. N. Gurzov. 2011. Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic -cell apoptosis through STAT1-mediated Bim protein activation. J. Biol. Chem. 286: 39632-39643. DOI ScienceOn |