1 |
WHO: Global Tubercalosis Control 2010. Geneva: WHO; 2010. 7.
|
2 |
Pieters J: Mycobacterium tuberculosis and the macrophage: maintaining a balance. Cell Host Microbe 3;399-407, 2008.
DOI
ScienceOn
|
3 |
Flynn JL, Chan J: Tuberculosis: latency and reactivation. Infect Immun 69;4195-4201, 2001.
DOI
ScienceOn
|
4 |
Zaiou M: Multifunctional antimicrobial peptides: therapeutic targets in several human diseases. J Mol Med 85; 317-329, 2007.
DOI
ScienceOn
|
5 |
Liu PT, Modlin RL: Human macrophage host defense against Mycobacterium tuberculosis. Curr Opin Immunol 20;371-376, 2008.
DOI
ScienceOn
|
6 |
Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, Ochoa MT, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zugel U, Gallo RL, Eisenberg D, Hewison M, Hollis BW, Adams JS, Bloom BR, Modlin RL: Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 311; 1770-1773, 2006.
DOI
ScienceOn
|
7 |
Hansdottir S, Monick MM, Hinde SL, Lovan N, Look DC, Hunninghake GW: Respiratory epithelial cells convert inactive vitamin D to its active form: potential effects on host defense. J Immunol 181;7090-7099, 2008.
DOI
|
8 |
Cole AM, Waring AJ: The role of defensins in lung biology and therapy. Am J Respir Med 1; 249-259, 2002.
DOI
ScienceOn
|
9 |
Liu PT, Schenk M, Walker VP, Dempsey PW, Kanchanapoomi M, Wheelwright M, Vazirnia A, Zhang X, Steinmeyer A, Zugel U, Hollis BW, Cheng G, Modlin RL: Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses. PLoS One 4;e5-810, 2009.
|
10 |
Jo EK: Innate immunity to mycobacteria: vitamin D and autophagy. Cell Microbiol 12;1026-1035, 2010.
DOI
ScienceOn
|
11 |
Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, Deretic V: Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 119;753-766, 2004.
DOI
ScienceOn
|
12 |
Shin DM, Yuk JM, Lee HM, Lee SH, Son JW, Harding CV, Kim JM, Modlin RL, Jo EK: Mycobacterial lipoprotein activates autophagy via TLR2/1/CD14 and a functional vitamin D receptor signalling. Cell Microbiol 12;1648-1665, 2010.
DOI
ScienceOn
|
13 |
De Yang, Chen Q, Schmidt AP, Anderson GM, Wang JM, Wooters J, Oppenheim JJ, Chertov O: LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells. J Exp Med 192;1069-1074, 2000.
DOI
ScienceOn
|
14 |
Kurosaka K, Chen Q, Yarovinsky F, Oppenheim JJ, Yang D: Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant. J Immunol 174;6257-6265, 2005.
DOI
|
15 |
Edfeldt K, Liu PT, Chun R, Fabri M, Schenk M, Wheelwright M, Keegan C, Krutzik SR, Adams JS, Hewison M, Modlin RL: T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism. Proc Natl Acad Sci U S A 107;22593-22598, 2010.
DOI
ScienceOn
|
16 |
Ganz T: Antimicrobial polypeptides in host defense of the respiratory tract. J Clin Invest 109;693-697, 2002.
DOI
|
17 |
Martineau AR, Newton SM, Wilkinson KA, Kampmann B, Hall BM, Nawroly N, Packe GE, Davidson RN, Griffiths CJ, Wilkinson RJ: Neutrophil-mediated innate immune resistance to mycobacteria. J Clin Invest 117;1988-1994, 2007.
DOI
ScienceOn
|
18 |
Oppenheim JJ, Biragyn A, Kwak LW, Yang D: Roles of antimicrobial peptides such as defensins in innate and adaptive immunity. Ann Rheum Dis 62(Suppl 2);ii17-21, 2003.
|
19 |
Kai-Larsen Y, Agerberth B: The role of the multifunctional peptide LL-37 in host defense. Front Biosci 13;3760-3767, 2008.
|
20 |
Rivas-Santiago B, Hernandez-Pando R, Carranza C, Juarez E, Contreras JL, Aguilar-Leon D, Torres M, Sada E: Expression of cathelicidin LL-37 during Mycobacterium tuberculosis infection in human alveolar macrophages, monocytes, neutrophils, and epithelial cells. Infect Immun 76;935-941, 2008.
DOI
ScienceOn
|
21 |
Bals R, Wang X, Zasloff M, Wilson JM: The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. Proc Natl Acad Sci U S A 95;9541-9546, 1998.
DOI
ScienceOn
|
22 |
Agerberth B, Grunewald J, Castanos-Velez E, Olsson B, Jornvall H, Wigzell H, Eklund A, Gudmundsson GH: Antibacterial components in bronchoalveolar lavage fluid from healthy individuals and sarcoidosis patients. Am J Respir Crit Care Med 160;283-290, 1999.
DOI
ScienceOn
|
23 |
Lee HM, Shin DM, Choi DK, Lee ZW, Kim KH, Yuk JM, Kim CD, Lee JH, Jo EK: Innate immune responses to Mycobacterium ulcerans via toll-like receptors and dectin-1 in human keratinocytes. Cell Microbiol 11;678-692, 2009.
DOI
ScienceOn
|
24 |
Yang CS, Shin DM, Kim KH, Lee ZW, Lee CH, Park SG, Bae YS, Jo EK: NADPH oxidase 2 interaction with TLR2 is required for efficient innate immune responses to mycobacteria via cathelicidin expression. J Immunol 182;3696-3705, 2009.
DOI
ScienceOn
|
25 |
Mendez-Samperio P, Perez A, Torres L: Role of reactive oxygen species (ROS) in Mycobacterium bovis bacillus Calmette Guérin-mediated up-regulation of the human cathelicidin LL-37 in A549 cells. Microb Pathog 47;252-257, 2009.
DOI
ScienceOn
|
26 |
Jacobsen M, Repsilber D, Gutschmidt A, Neher A, Feldmann K, Mollenkopf HJ, Ziegler A, Kaufmann SH: Candidate biomarkers for discrimination between infection and disease caused by Mycobacterium tuberculosis. J Mol Med (Berl) 85;613-621, 2007.
DOI
ScienceOn
|
27 |
Sow FB, Florence WC, Satoskar AR, Schlesinger LS, Zwilling BS, Lafuse WP: Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis. J Leukoc Biol 82;934-945, 2007.
DOI
ScienceOn
|
28 |
Beisswenger C, Bals R: Functions of antimicrobial peptides in host defense and immunity. Curr Protein Pept Sci 6; 255-264, 2005.
DOI
ScienceOn
|
29 |
Wilson CL, Ouellette AJ, Satchell DP, Ayabe T, Lopez- Boado YS, Stratman JL, Hultgren SJ, Matrisian LM, Parks WC: Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. Science 286;113-117, 1999.
DOI
|
30 |
Schutte BC, Mitros JP, Bartlett JA, Walters JD, Jia HP, Welsh MJ, Casavant TL, McCray PB Jr: Discovery of five conserved beta -defensin gene clusters using a computational search strategy. Proc Natl Acad Sci U S A 99;2129-2133, 2002.
DOI
ScienceOn
|
31 |
Kalita A, Verma I, Khuller GK: Role of human neutrophil peptide-1 as a possible adjunct to antituberculosis chemotherapy. J Infect Dis 190;1476-1480, 2004.
DOI
ScienceOn
|
32 |
Zanetti M: Cathelicidins, multifunctional peptides of the innate immunity. J Leukoc Biol 75;39-48, 2004.
DOI
|
33 |
Lehrer RI, Ganz T: Cathelicidins: a family of endogenous antimicrobial peptides. Curr Opin Hematol 9;18-22, 2002.
DOI
ScienceOn
|
34 |
Zanetti M: The role of cathelicidins in the innate host defenses of mammals. Curr Issues Mol Biol 7:179-196, 2005.
|
35 |
Fahy RJ, Wewers MD: Pulmonary defense and the human cathelicidin hCAP-18/LL-37. Immunol Res 31;75-89, 2005.
DOI
|
36 |
Lai Y, Gallo RL: AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense. Trends Immunol 30;131-141, 2009.
DOI
ScienceOn
|
37 |
Yuk JM, Shin DM, Lee HM, Yang CS, Jin HS, Kim KK, Lee ZW, Lee SH, Kim JM, Jo EK: Vitamin D3 induces autophagy in human monocytes/macrophages via cathelicidin. Cell Host Microbe 6;231-243, 2009.
DOI
ScienceOn
|
38 |
Lehrer RI, Lichtenstein AK, Ganz T: Defensins: antimicrobial and cytotoxic peptides of mammalian cells. Annu Rev Immunol 11;105-128, 1993.
DOI
ScienceOn
|
39 |
Driss V, Legrand F, Hermann E, Loiseau S, Guerardel Y, Kremer L, Adam E, Woerly G, Dombrowicz D, Capron M: TLR2-dependent eosinophil interactions with mycobacteria: role of alpha-defensins. Blood 113;3235-3244, 2009.
DOI
ScienceOn
|
40 |
Kisich KO, Heifets L, Higgins M, Diamond G: Antimycobacterial agent based on mRNA encoding human beta-defensin 2 enables primary macrophages to restrict growth of Mycobacterium tuberculosis. Infect Immun 69;2692-2699, 2001.
DOI
ScienceOn
|
41 |
Yang D, Chertov O, Bykovskaia SN, Chen Q, Buffo MJ, Shogan J, Anderson M, Schroder JM, Wang JM, Howard OM, Oppenheim JJ: Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science 286;525-528, 1999.
DOI
ScienceOn
|
42 |
De Smet K, Contreras R: Human antimicrobial peptides: defensins, cathelicidins and histatins. Biotechnol Lett 27; 1337-1347, 2005.
DOI
ScienceOn
|
43 |
O'Neil DA, Porter EM, Elewaut D, Anderson GM, Eckmann L, Ganz T, Kagnoff MF: Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium. J Immunol 163;6718-6724, 1999.
|
44 |
Ganz T: Hepcidin--a peptide hormone at the interface of innate immunity and iron metabolism. Curr Top Microbiol Immunol 306;183-198, 2006.
|
45 |
Becker MN, Diamond G, Verghese MW, Randell SH: CD14- dependent lipopolysaccharide-induced beta-defensin-2 expression in human tracheobronchial epithelium. J Biol Chem 275;29731-29736, 2000.
DOI
|
46 |
Brandt CR, Akkarawongsa R, Altmann S, Jose G, Kolb AW, Waring AJ, Lehrer RI: Evaluation of a theta-defensin in a Murine model of herpes simplex virus type 1 keratitis. Invest Ophthalmol Vis Sci 48;5118-5124, 2007.
DOI
ScienceOn
|
47 |
Wang W, Cole AM, Hong T, Waring AJ, Lehrer RI: Retrocyclin, an antiretroviral theta-defensin, is a lectin. J Immunol 170;4708-4716, 2003.
DOI
|
48 |
Yang C, Boone L, Nguyen TX, Rudolph D, Limpakarnjanarat K, Mastro TD, Tappero J, Cole AM, Lal RB: Theta-Defensin pseudogenes in HIV-1-exposed, persistently seronegative female sex-workers from Thailand. Infect Genet Evol 5;11-15, 2005.
DOI
ScienceOn
|
49 |
Ganz T: Hepcidin and its role in regulating systemic iron metabolism. Hematology Am Soc Hematol Educ Program 29-35, 2006.
|
50 |
Ganz T, Nemeth E: Iron sequestration and anemia of inflammation. Semin Hematol 46;387-393, 2009.
DOI
ScienceOn
|
51 |
Nemeth E, Ganz T: The role of hepcidin in iron metabolism. Acta Haematol 122;78-86, 2009.
DOI
ScienceOn
|
52 |
Atanasiu V, Manolescu B, Stoian I: Hepcidin the link between inflammation and anemia in chronic renal failure. Rom J Intern Med 44;25-33, 2006.
|
53 |
Sow FB, Alvarez GR, Gross RP, Satoskar AR, Schlesinger LS, Zwilling BS, Lafuse WP: Role of STAT1, NF-kappaB, and C/EBPbeta in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFNgamma. J Leukoc Biol 86;1247-258, 2009.
DOI
ScienceOn
|
54 |
Harder J, Meyer-Hoffert U, Teran LM, Schwichtenberg L, Bartels J, Maune S, Schröder JM: Mucoiod Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia. Am J Respir Cell Mol Biol 22;714-721, 2000.
DOI
ScienceOn
|
55 |
Mendez-Samperio P, Miranda E, Trejo A: Mycobacterium bovis Bacillus Calmette-Guérin (BCG) stimulates human beta- defensin-2 gene transcription in human epithelial cells. Cell Immunol 239;61-66, 2006
DOI
ScienceOn
|
56 |
Rivas-Santiago CE, Rivas-Santiago B, Leon DA, Castaneda- Delgado J, Hernadez Pando R: Induction of -defensins by l-isoleucine as novel immunotherapy in experimental murine tuberculosis. Clin Exp Immunol 164;80-89, 2011.
DOI
ScienceOn
|
57 |
Tang YQ, Yuan J, Osapay G, Osapay K, Tran D, Miller CJ, Ouellette AJ, Selsted ME: A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins. Science 286;498-502, 1999.
DOI
|
58 |
Aguilar Leon D, Zumárraga MJ, Jimenez Oropeza R, Gioffre AK, Bernardelli A, Orozco Estevez H, Cataldi AA, Hernández Pando R: Mycobacterium bovis with different genotypes and from different hosts induce dissimilar immunopathological lesions in a mouse model of tuberculosis. Clin Exp Immunol 157;139-147, 2009.
DOI
ScienceOn
|
59 |
Rivas-Santiago B, Sada E, Tsutsumi V, Aguilar-Leon D, Contreras JL, Hernandez-Pando R: beta-Defensin gene expression during the course of experimental tuberculosis infection. J Infect Dis 194;697-701, 2006.
DOI
ScienceOn
|
60 |
Cole AM, Wang W, Waring AJ, Lehrer RI: Retrocyclins: using past as prologue. Curr Protein Pept Sci 5;373-381, 2004.
DOI
ScienceOn
|
61 |
Leonova L, Kokryakov VN, Aleshina G, Hong T, Nguyen T, Zhao C, Waring AJ, Lehrer RI: Circular minidefensins and posttranslational generation of molecular diversity. J Leukoc Biol 70;461-464, 2001.
|
62 |
Tran D, Tran PA, Tang YQ, Yuan J, Cole T, Selsted ME: Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides. J Biol Chem 277;3079-3084, 2002.
DOI
|