| 1 |
Iwashima M, Irving BA, van Oers NS, Chan AC, Weiss A: Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science 263;1136-1139, 1994
DOI
PUBMED
|
| 2 |
Bubeck Wardenburg J, Pappu R, Bu JY, Mayer B, Chernoff J, Straus D, Chan AC: Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76. Immunity 9;607-616, 1998
DOI
ScienceOn
|
| 3 |
Raab M, da Silva AJ, Findell PR, Rudd CE: Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/ CD3 induction of interleukin-2. Immunity 6;155-164, 1997
DOI
ScienceOn
|
| 4 |
Wu J, Motto DG, Koretzky GA, Weiss A: Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. Immunity 4;593-602, 1996
DOI
ScienceOn
|
| 5 |
da Silva AJ, Li Z, de Vera C, Canto E, Findell P, Rudd CE: Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production. Proc Natl Acad Sci U S A 94;7493-7498, 1997
DOI
ScienceOn
|
| 6 |
Bunnell SC, Hong DI, Kardon JR, Yamazaki T, McGlade CJ, Barr VA, Samelson LE: T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J Cell Biol 158;1263-1275, 2002
DOI
ScienceOn
|
| 7 |
Clements JL, Yang B, Ross-Barta SE, Eliason SL, Hrstka RF, Williamson RA, Koretzky GA: Requirement for the leukocyte- specific adapter protein SLP-76 for normal T cell development. Science 281;416-419, 1998
DOI
PUBMED
ScienceOn
|
| 8 |
Maltzman JS, Kovoor L, Clements JL, Koretzky GA: Conditional deletion reveals a cell-autonomous requirement of SLP-76 for thymocyte selection. J Exp Med 202;893-900, 2005
DOI
ScienceOn
|
| 9 |
Judd BA, Myung PS, Obergfell A, Myers EE, Cheng AM, Watson SP, Pear WS, Allman D, Shattil SJ, Koretzky GA: Differential requirement for LAT and SLP-76 in GPVI versus T cell receptor signaling. J Exp Med 195;705-717, 2002
DOI
ScienceOn
|
| 10 |
Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A: LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity 9;617-626, 1998
DOI
ScienceOn
|
| 11 |
Peterson EJ, Woods ML, Dmowski SA, Derimanov G, Jordan MS, Wu JN, Myung PS, Liu QH, Pribila JT, Freedman BD, Shimizu Y, Koretzky GA: Coupling of the TCR to integrin activation by Slap-130/Fyb. Science 293;2263-2265, 2001
DOI
PUBMED
ScienceOn
|
| 12 |
Myung PS, Derimanov GS, Jordan MS, Punt JA, Liu QH, Judd BA, Meyers EE, Sigmund CD, Freedman BD, Koretzky GA: Differential requirement for SLP-76 domains in T cell development and function. Immunity 15;1011-1026, 2001
DOI
ScienceOn
|
| 13 |
Abtahian F, Bezman N, Clemens R, Sebzda E, Cheng L, Shattil SJ, Kahn ML, Koretzky GA: Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells. Mol Cell Biol 26;6936-6949, 2006
DOI
ScienceOn
|
| 14 |
Marie-Cardine A, Hendricks-Taylor LR, Boerth NJ, Zhao H, Schraven B, Koretzky GA: Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130. J Biol Chem 273;25789-25795, 1998
DOI
PUBMED
|
| 15 |
Lafuente EM, van Puijenbroek AA, Krause M, Carman CV, Freeman GJ, Berezovskaya A, Constantine E, Springer TA, Gertler FB, Boussiotis VA: RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion. Dev Cell 7;585-595, 2004
DOI
ScienceOn
|
| 16 |
Katagiri K, Hattori M, Minato N, Kinashi T: Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses. Mol Cell Biol 22;1001-1015, 2002
DOI
ScienceOn
|
| 17 |
Jordan MS, Smith JE, Burns JC, Austin JE, Nichols KE, Aschenbrenner AC, Koretzky GA: Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76. Immunity 28;359-369, 2008
DOI
ScienceOn
|
| 18 |
Jackman JK, Motto DG, Sun Q, Tanemoto M, Turck CW, Peltz GA, Koretzky GA, Findell PR: Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells. J Biol Chem 270;7029-7032, 1995
DOI
ScienceOn
|
| 19 |
Bezman N, Koretzky GA: Compartmentalization of ITAM and integrin signaling by adapter molecules. Immunol Rev 218;9-28, 2007
DOI
ScienceOn
|
| 20 |
Liu Q, Berry D, Nash P, Pawson T, McGlade CJ, Li SS: Structural basis for specific binding of the Gads SH3 domain to an RxxK motif-containing SLP-76 peptide: a novel mode of peptide recognition. Mol Cell 11;471-481, 2003
DOI
ScienceOn
|
| 21 |
Sauer K, Liou J, Singh SB, Yablonski D, Weiss A, Perlmutter RM: Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes. J Biol Chem 276; 45207-45216, 2001
DOI
ScienceOn
|
| 22 |
Han J, Lim CJ, Watanabe N, Soriani A, Ratnikov B, Calderwood DA, Puzon-McLaughlin W, Lafuente EM, Boussiotis VA, Shattil SJ, Ginsberg MH: Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3. Curr Biol 16;1796-1806, 2006
DOI
ScienceOn
|
| 23 |
Motto DG, Ross SE, Wu J, Hendricks-Taylor LR, Koretzky GA: Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production. J Exp Med 183;1937-1943, 1996
DOI
ScienceOn
|
| 24 |
Fuller CL, Braciale VL, Samelson LE: All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton. Immunol Rev 191;220-236, 2003
DOI
ScienceOn
|
| 25 |
Takagi J, Springer TA: Integrin activation and structural rearrangement. Immunol Rev 186;141-163, 2002
DOI
ScienceOn
|
| 26 |
Tuosto L, Michel F, Acuto O: p95vav associates with tyrosine- phosphorylated SLP-76 in antigen-stimulated T cells. J Exp Med 184;1161-1166, 1996
DOI
ScienceOn
|
| 27 |
Pivniouk V, Tsitsikov E, Swinton P, Rathbun G, Alt FW, Geha RS: Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell 94;229-238, 1998
DOI
ScienceOn
|
| 28 |
Kumar L, Pivniouk V, de la Fuente MA, Laouini D, Geha RS: Differential role of SLP-76 domains in T cell development and function. Proc Natl Acad Sci U S A 99;884-889, 2002
DOI
ScienceOn
|
| 29 |
Sebzda E, Bracke M, Tugal T, Hogg N, Cantrell DA: Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling. Nat Immunol 3;251-258, 2002
DOI
ScienceOn
|
| 30 |
Wu JN, Jordan MS, Silverman MA, Peterson EJ, Koretzky GA: Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function. J Immunol 172;6768-6774, 2004
DOI
PUBMED
|
| 31 |
Musci MA, Hendricks-Taylor LR, Motto DG, Paskind M, Kamens J, Turck CW, Koretzky GA: Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases. J Bio Chem 272;11674-11677, 1997
DOI
ScienceOn
|
| 32 |
Abtahian F, Guerriero A, Sebzda E, Lu MM, Zhou R, Mocsai A, Myers EE, Huang B, Jackson DG, Ferrari VA, Tybulewicz V, Lowell CA, Lepore JJ, Koretzky GA, Kahn ML: Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk. Science 299;247-251, 2003
DOI
PUBMED
ScienceOn
|
| 33 |
Di Bartolo V, Montagne B, Salek M, Jungwirth B, Carrette F, Fourtane J, Sol-Foulon N, Michel F, Schwartz O, Lehmann WD, Acuto O: A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76. J Exp Med 204;681-691, 2007
DOI
ScienceOn
|
| 34 |
Kliche S, Breitling D, Togni M, Pusch R, Heuer K, Wang X, Freund C, Kasirer-Friede A, Menasche G, Koretzky GA, Schraven B: The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1. Mol Cell Biol 26;7130-7144, 2006
DOI
ScienceOn
|
| 35 |
Huang Y, Norton DD, Precht P, Martindale JL, Burkhardt JK, Wange RL: Deficiency of ADAP/Fyb/SLAP-130 destabilizes SKAP55 in Jurkat T cells. J Biol Chem 280;23576-23583, 2005
DOI
ScienceOn
|
| 36 |
Yablonski D, Kadlecek T, Weiss A: Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT. Mol Cell Biol 21;4208-4218, 2001
DOI
ScienceOn
|
| 37 |
Kettner A, Pivniouk V, Kumar L, Falet H, Lee JS, Mulligan R, Geha RS: Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells. Mol Cell Biol 23;2395-2406, 2003
DOI
ScienceOn
|
| 38 |
Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE: LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 92;83-92, 1998
DOI
ScienceOn
|
| 39 |
Griffiths EK, Krawczyk C, Kong YY, Raab M, Hyduk SJ, Bouchard D, Chan VS, Kozieradzki I, Oliveira-Dos-Santos AJ, Wakeham A, Ohashi PS, Cybulsky MI, Rudd CE, Penninger JM: Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap. Science 293;2260-2263, 2001
DOI
PUBMED
ScienceOn
|
| 40 |
Menasche G, Kliche S, Chen EJ, Stradal TE, Schraven B, Koretzky G: RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activation. Mol Cell Biol 27;4070-4081, 2007
DOI
ScienceOn
|
| 41 |
June CH, Fletcher MC, Ledbetter JA, Schieven GL, Siegel JN, Phillips AF, Samelson LE: Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction. Proc Natl Acad Sci U S A 87;7722-7726, 1990
DOI
ScienceOn
|
| 42 |
Marie-Cardine A, Bruyns E, Eckerskorn C, Kirchgessner H, Meuer SC, Schraven B: Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes. J Biol Chem 272; 16077-16080, 1997
DOI
ScienceOn
|
| 43 |
Jordan MS, Maltzman JS, Kliche S, Shabason J, Smith JE, Obstfeld A, Schraven B, Koretzky GA: In vivo disruption of T cell development by expression of a dominant-negative polypeptide designed to abolish the SLP-76/Gads interaction. Eur J Immunol 37;2961-2972, 2007
DOI
ScienceOn
|
| 44 |
Bos JL: Linking Rap to cell adhesion. Curr Opin Cell Biol 17;123-128, 2005
DOI
PUBMED
ScienceOn
|
| 45 |
Bezman NA, Lian L, Abrams CS, Brass LF, Kahn ML, Jordan MS, Koretzky GA: Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo. J Exp Med 205;1775-1788, 2008
DOI
ScienceOn
|
| 46 |
Sebzda E, Hibbard C, Sweeney S, Abtahian F, Bezman N, Clemens G, Maltzman JS, Cheng L, Liu F, Turner M, Tybulewicz V, Koretzky GA, Kahn ML: Syk and Slp-76 mutant mice reveal a cell-autonomous hematopoietic cell contribution to vascular development. Dev Cell 11;349-361, 2006
DOI
ScienceOn
|
| 47 |
Clements JL, Ross-Barta SE, Tygrett LT, Waldschmidt TJ, Koretzky GA: SLP-76 expression is restricted to hemopoietic cells of monocyte, granulocyte, and T lymphocyte lineage and is regulated during T cell maturation and activation. J Immunol 161;3880-3889, 1998
PUBMED
|
| 48 |
Katagiri K, Hattori M, Minato N, Irie S, Takatsu K, Kinashi T: Rap1 is a potent activation signal for leukocyte function- associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase. Mol Cell Biol 20;1956-1969, 2000
DOI
ScienceOn
|
| 49 |
Bunnell SC, Diehn M, Yaffe MB, Findell PR, Cantley LC, Berg LJ: Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade. J Biol Chem 275;2219-2230, 2000
DOI
ScienceOn
|
| 50 |
Smith-Garvin JE, Koretzky GA, Jordan MS: T Cell activation. Annu Rev Immunol 27;591-619, 2009
DOI
ScienceOn
|
| 51 |
Yokosuka T, Sakata-Sogawa K, Kobayashi W, Hiroshima M, Hashimoto-Tane A, Tokunaga M, Dustin ML, Saito T: Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. Nat Immunol 6;1253-1262, 2005
DOI
ScienceOn
|
| 52 |
Onodera H, Motto DG, Koretzky GA, Rothstein DM: Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase. J Biol Chem 271;22225-22230, 1996
DOI
ScienceOn
|
| 53 |
Silverman MA, Shoag J, Wu J, Koretzky GA: Disruption of SLP-76 interaction with Gads inhibits dynamic clustering of SLP-76 and FcepsilonRI signaling in mast cells. Mol Cell Biol 26;1826-1838, 2006
DOI
ScienceOn
|
| 54 |
Jordan MS, Sadler J, Austin JE, Finkelstein LD, Singer AL, Schwartzberg PL, Koretzky GA: Functional hierarchy of the N-terminal tyrosines of SLP-76. J Immunol 176;2430-2438, 2006
DOI
PUBMED
|
| 55 |
Wunderlich L, Farago A, Downward J, Buday L: Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes. Eur J Immunol 29;1068-1075, 1999
DOI
ScienceOn
|
| 56 |
Koretzky GA, Abtahian F, Silverman MA: SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond. Nat Rev Immunol 6;67-78, 2006
DOI
ScienceOn
|
| 57 |
Pivniouk VI, Martin TR, Lu-Kuo JM, Katz HR, Oettgen HC, Geha RS: SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells. J Clin Invest 103;1737-1743, 1999
|
| 58 |
Liu SK, Fang N, Koretzky GA, McGlade CJ: The hematopoietic- specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors. Curr Biol 9;67-75, 1999
DOI
ScienceOn
|
| 59 |
Seet BT, Berry DM, Maltzman JS, Shabason J, Raina M, Koretzky GA, McGlade CJ, Pawson T: Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motif. Embo
J 26;678-689, 2007
PUBMED
|
| 60 |
Boerth NJ, Sadler JJ, Bauer DE, Clements JL, Gheith SM, Koretzky GA: Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling. J Exp Med 192;1047-1058, 2000
DOI
ScienceOn
|
| 61 |
Newbrough SA, Mocsai A, Clemens RA, Wu JN, Silverman MA, Singer AL, Lowell CA, Koretzky GA: SLP-76 regulates Fcgamma receptor and integrin signaling in neutrophils. Immunity 19;761-769, 2003
DOI
PUBMED
ScienceOn
|
| 62 |
Judd BA, Myung PS, Leng L, Obergfell A, Pear WS, Shattil SJ, Koretzky GA: Hematopoietic reconstitution of SLP-76 corrects hemostasis and platelet signaling through alpha IIb beta 3 and collagen receptors. Proc Natl Acad Sci U S A 97;12056-12061, 2000
DOI
ScienceOn
|
| 63 |
Su YW, Zhang Y, Schweikert J, Koretzky GA, Reth M, Wienands J: Interaction of SLP adaptors with the SH2 domain of Tec family kinases. Eur J Immunol 29;3702-3711, 1999
DOI
ScienceOn
|
| 64 |
Samelson LE: Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins. Annu Rev Immunol 20;371-394, 2002
DOI
PUBMED
ScienceOn
|
| 65 |
Yablonski D, Kuhne MR, Kadlecek T, Weiss A: Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell. Science 281;413-416, 1998
DOI
PUBMED
ScienceOn
|
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