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http://dx.doi.org/10.5573/ieie.2014.51.9.190

A Study on the Action Potential Generations of the Vestibular Hair Cell Model with Negative Stiffness Feature  

Kim, Dongyoung (Dept. of Electronic Engineering, Inha University)
Hong, Kihwan (Institute for Information and Electronics Research(IIER), Inha University)
Kim, Kyu-Sung (Dept. of Otolaryngology-Head & Neck Surgery, Inha University Hospital)
Lee, Sangmin (Institute for Information and Electronics Research(IIER) & Dept. of Electronic Engineering, Inha University)
Publication Information
Journal of the Institute of Electronics and Information Engineers / v.51, no.9, 2014 , pp. 190-199 More about this Journal
Abstract
In this paper, the vestibular hair bundle feature model and integrated vestibular hair cell model were proposed. In conventional modeling studies of vestibular system, only partial mechanisms were modeled, such as the characteristics of the vestibular hair bundles without external forces or the action potential of synapse, and the study about action potential of vestibular afferent considering the characteristics of the vestibular hair bundle was not performed. The proposed integrated vestibular hair cell model reflects external forces considering negative stiffness features of each hair bundles with different regularities of hair cells and our model was compared with conventional model without external forces. As a result, irregular afferent and intermediate afferent with high ratio of firing frequency variations to the changes of external stimulation had small width of negative stiffness section, but the width of the negative stiffness of regular afferent with low ratio was similar to that of conventional negative stiffness features. And the proposed integrated vestibular hair cell model showed almost same results with conventional data with animal experiments in 11 chosen frequency bands. It is verified that our proposed hair bundle feature model is adequately modeled.
Keywords
vestibular hair cells; negative stiffness; afterhyperpolarization(AHP) model; vestibular afferents; action potentials;
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Times Cited By KSCI : 1  (Citation Analysis)
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