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Development of Excitation Light Source for Photodynamic Diagnosis of Cancer  

Lim, Hyun-Soo (Department of Biomedical Engineering, Chungnam Natinal University)
Publication Information
Journal of the Institute of Electronics Engineers of Korea SC / v.44, no.6, 2007 , pp. 49-56 More about this Journal
Abstract
In this paper, the development of excitation light source is proposed for excitation light of the photodynamic therapy of cancer. Since the selection of the wavelength band of excitation light has an interrelation with fluorescence generation according to the selection of a photosensitizer. This study aims at designing and evaluating light source that can stably generate light with various kinds of wavelengths in order to make possible photodynamic diagnosis using a photosensitizer and diagnosis using auto-fluorescence. The light source device was a Xenon lamp and filter wheel, composed of an optical output control through iris and filters with several wavelength bands. It also makes the inducement of auto-fluorescence possible because it is designed to generate a wavelength band of 380-420nm, 430-480nm, 480-560nm. The transmission part of the light source was developed to enhance the efficiency of light transmission. To evaluate this light source device by KFDA#s technical reference, the characteristics of the light output and wavelength band were found.
Keywords
PDD; Xenon Lamp; Multi-Wavelength; Photosensitizer; Auto- Fluorescence;
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Times Cited By KSCI : 1  (Citation Analysis)
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