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Numerical Analysis of Electric Field Distribution Induced Inside a Realistic Brain Model Considering Conductivity Heterogeneity  

Kim, Dong-Hun (경북대학교 전기공학과)
Lee, Il-Ho (경북대학교 전기공학과)
Won, Chul-Ho (경일대학교)
Publication Information
The Transactions of The Korean Institute of Electrical Engineers / v.57, no.2, 2008 , pp. 314-319 More about this Journal
Abstract
In this paper, the electric field distribution induced inside the brain during Transcranial Magnetic Stimulation(TMS) has been thoroughly investigated in terms of tissue heterogeneity and anisotropy as well as different head models. To achieve this, first, an elaborate head model consisting of seven major parts of the head has been built based on the Magnetic Resonance(MR) image data. Then the Finite Element Method(FEM) has been used to evaluate the electric field distribution under different head models or three different conductivity conditions when the head model has been exposed to a time varying magnetic field achieved by utilizing the Figure-Of-Eight(FOE) stimulation coil. The results show that the magnitude as well as the distribution of the induced field is significantly affected by the degree of geometrical asymmetry of head models and conductivity conditions with respect to the center of the FOE coil.
Keywords
Brain Model; Finite Element Analysis; Induced Electric Field; Transcranial Magnetic Stimulation;
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1 R. Liu and S. Ueno, "Calculating the activation function of nerve excitation in inhomogeneous volume conductor during magnetic stimulation using the finite element method," IEEE Trans. Magn., vol. 36, pp.1796-1799, July 2000   DOI   ScienceOn
2 J. Starzynski, B. Sawicki, S. Wincenciak, A. Krawczyk and T. Zyss, 'Simulation of Magnetic Stimulation of the Brain,' IEEE Trans. Magn., vol. 38, pp.1237-1240, March 2002   DOI   ScienceOn
3 M. Hallett, "Transcranial magnetic stimulation and the human brain," Nature, vol. 406, pp. 147-150, 2000   DOI   ScienceOn
4 J. S. Yuan and Z. H. Tang, "Finite-Element simulation of Human Brain Electric Activity," IEEE Trans. Magn., vol. 39, pp.1539-1542, 2003   DOI   ScienceOn
5 D-H Kim and G. E. Georghiou and C. Won, "Improved Field Localization in Transcranial Magnetic Stimulation of the Brain With the Utilization of a Conductive Shield Plate in the Stimulator," IEEE Trans. Biomed. Eng., vol. 53, pp.720-725, 2006   DOI   ScienceOn
6 W. Wang and S. R. Eisenberg, "A three-dimensional finite element method for computing magnetically induced currents in tissues," IEEE Trans. Magn., vol. 30, pp. 5015-5023, Nov. 1994   DOI   ScienceOn
7 K. R. Davey, D. H. Cheng and C. M. Epstein, "Prediction of magnetically induced electric fields in biological tissue", IEEE Trans. Biomed. Eng., vol. 38, pp. 418-422, 1991   DOI   ScienceOn
8 Vector Fields Limited, OPERA User's Guide (2005)
9 Dong-Hun Kim and Chulho Won and G. E. Georghiou, "Assessment of the Sensitivity to Field Localization of Various Parameters during Transcranial Magnetic Stimulation," IEEE Trans. Magn., vol. 43, pp.4016-4022, 2007   DOI   ScienceOn
10 G. Huiskamp, M. Vroeijenstijn, R. van Dijk, G. Wieneke, and A. Huffelen, "The need for correct realistic geometry in the inverse EEG problem" IEEE Trans. Biomed. Eng., vol 46, pp.1281-1287, Nov 1999   DOI   ScienceOn
11 I. G. Zubal, C. R. Harrell, E. O. Smith, Z. Rattner, G. Gindi and P. B. Hoffer, "Computerized 3-Dimensional Segmented Human Anatomy," Medical Physics, vol. 21, pp. 299-302, 1994   DOI   ScienceOn
12 P. C. Miranda, M. Hallett and P. J. Basser, The Electric Field Induced in the Brain by Magnetic Stimulation : A 3-D Finite Element Analysis of the Effect of Tissue Heterogeneity and Anisotropy," IEEE Trans. Biomed. Eng., vol. 50, pp.1074-7085, Sept 2003   DOI   ScienceOn