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Electrochemical Detection of Hydrogen Peroxide based on Viologen Monolayers  

Choi, Won-Suk (동아대학교 나노공학과)
Lee, Dong-Yun (동아대학교 전기공학과)
Park, Sang-Hyun (동아인재대 응급구조과)
Park, Jae-Chul (영진전문대 전자정보계열)
Kwon, Young-Soo (동아대학교 전기공학과)
Publication Information
The Transactions of The Korean Institute of Electrical Engineers / v.57, no.11, 2008 , pp. 2006-2010 More about this Journal
Abstract
In this paper, we fabricated a biosensor for detecting hydrogen peroxide and investigated the sensing property. We prepared a viologen and hemoglobin modified gold electrode using self-assembly and layer by layer method. The electrochemical property of the viologen derivative was characterized in 0.1 M $NaClO_4$ electrolyte solution by cyclic voltammetry. The modified electrode showed reversible electrochemical properties and high stability. From the results, the viologen can act as a charge transfer mediator for access to the electrode surface. The catalytic characteristics of the designed sensor proved that hemoglobin has been kept in its natural structure and can retain its biological activity. The designed biosensor showed a fast amperometric response, excellent linearity and low detection limit. In addition, it had high sensitivity, good reproducibility and stability.
Keywords
Hydrogen peroxide; Viologen; Hemoglobin; Cyclic voltammetry; Detection limit;
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