Browse > Article

Mixture Toxicity Test of Ten Major Chemicals Using Daphnia magna by Response Curve Method  

Ra, Jin-Sung (Gwangju Institute of Science and Technology, Department of Environmental Science and Engineering)
Kim, Ki-Tae (Gwangju Institute of Science and Technology, Department of Environmental Science and Engineering)
Kim, Sang-Don (Gwangju Institute of Science and Technology, Department of Environmental Science and Engineering)
Han, Sang-Guk (Division of Ocean System Engineering, Mokpo National Maritime University)
Chang, Nam-Ik (Yeongsan-river Environmental Research Laboratory)
Kim, Yong-Seok (Yeongsan-river Environmental Research Laboratory)
Publication Information
Journal of Korean Society of Environmental Engineers / v.27, no.1, 2005 , pp. 67-74 More about this Journal
Abstract
Toxicity tests were performed to evaluate the feasibility of application with prediction models to 10 mixture chemicals (chloroneb, butylbenzylphthalate, pendimethaline, di-n-butylphthalate, di-iso-butylphthalate, diazinon, isofenphos, 2-chlorophenol, 2,4,6-trichlorophenol and p-octylphenol) detected in effluents from wastewater treatment plants (WWTPs). Ten chemicals were selected in the basis of their toxicities to Daphnia magna and the concentrations in effluents measured by GC/MS. Three models including concentration addition (CA), independent action (IA) and effect summation (ES) were employed for the comparison of the predicted and the observed mortality of D. magna exposed to 10 mixture chemicals for 48 hours. With a comparative study it was ineffective to predict the mortality through the CA and the ES prediction model, while the IA prediction model showed a high correlation($r^2\;=\;0.85$). Moreover, the ES model over-estimated the toxicity observed by bioassay experiments about five-fold. Consequently, IA model is a reasonable tool to predict the mixture toxicity of the discharging water from WWTPs.
Keywords
Mixture Toxicity; Daphnia Magna; Toxicity Prediction Model;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Victor, D. V., Vallerie, C, Carol, D., Howard, C. B., Linda, A. D., David, E. H., 'Application of Whole Effluent Toxicity Test Procedures to Ambient Water Quality Assessment,' Environ. Toxicol. Chem., 19(1), 42-62(2000)   DOI
2 Michael, C, 'Mixtrue toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid,' Ecotox. Environ. Safe., in press
3 Roberta, G., 'Ecotoxicological and chemical evaluation of phenolic compounds in industrial effluents,' Chemosphere, 44, 1737-1747(2001)   DOI   ScienceOn
4 Faust, M., Altenburger, R., Backhaus, T., Blanck, H., Boedeker, W., Gramatica, P., Hamer, V., Scholze, M., Vighi, M., Grimme, L. H., Predicting the joint algal toxicity of multi-componunt s-trizine mixtures at low-effect concentrations of individual toxiciants, Aquat. Toxicol., 56, 13-32(2001)   DOI   ScienceOn
5 Faust, M., Altenburger, R., Backhaus, T., Blanck, H., Boedeker, W., Gramatica, P., Hamer, V., Scholze, M., Vighi, M., Grimme, L. H., Joint algal toxicity of 16 dissimilarly acting chemicals is predictable by the concept of independent action, Aquat. Toxicol., 63, pp. 43-63(2003)   DOI   ScienceOn
6 Cowgill, U. M. and Milazzo, D. P., The Sensitivity of Ceriodaphnia dubia and Daphnia magna to Seven Chemicals Utilizing the Three-Brood Test, Arch. Environ. Contam. Toxicol., 20(2), 211-217(1991)   DOI
7 Steven, W. G., Kari, L. F., Eric, T. K., Greg, S., Lou, R., and Dawn, A. K., 'Modification to the Algal Growth Inhibition Test for Use As a regulatory Assay,' Environ. Toxicol. Chem., 19(1), 36-41(2000)   DOI
8 Method for measuring the acute toxicity of effluents and receiving waters to freshwater and marin organism, EPA/600/4-90/027F(1993)
9 Kenneth, E. B., Sylvia, H. W., Cathy, M., and Kevin, A. T., 'Joint Acute toxicity of diazinon and copper to ceriodaphnia dubia,' Environ. Toxicol. Chem., 22(7), 1562-1567(2003)   DOI
10 Howard, C. B., Rick, K., James, R. E., Ann-Maree, M., Peta, H., Louise, T., and Adam, L., Whole Effluent Toxicity of Sewage Treatment Plants in the HAWKESBURY-NEPEAN WATERSHED, NEW SOUTH WALES, AUSTRALIA, to Ceriodaphnia dubia and Selenastrum Capricornutum, Environ. Toxicol. Chem., 19(1), 72-81(2000)   DOI
11 Backhaus, T., Scholze, M., Grimme, L. H., The single substance and mixture toxicity of quinolones to the bio-luminescent bacterium Vibrio fischeri, Aquat. Toxicol, 49, 49-61(2000)   DOI   ScienceOn
12 U.S. Environmental Protection Agency, ECOTOX database, http://www.epa.gov/ecotox