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http://dx.doi.org/10.4040/jkan.21188

Incidence and Risk Factors of Dyslipidemia after Menopause  

Jeong, Ihn Sook (College of Nursing, Pusan National University)
Yun, Hae Sun (Department of Nursing Science, Kyungsung University)
Kim, Myo Sung (Department of Nursing, Dong-Eui University)
Hwang, Youn Sun (Department of Nursing Science, Dongseo University)
Publication Information
Journal of Korean Academy of Nursing / v.52, no.2, 2022 , pp. 214-227 More about this Journal
Abstract
Purpose: This study was aimed at investigating the incidence and risk factors of dyslipidemia in menopausal women using a Korean community-based longitudinal study. Methods: The subjects were 245 postmenopausal women without dyslipidemia who had participated in the Ansan-Ansung cohort study from 2001~2002 (baseline) to 2015~2016 (seventh follow-up visit). The dyslipidemia incidence was measured as incidence proportion (%) and incidence rate per 100 person-years. The predictors of developing dyslipidemia were analyzed with Cox's proportional hazard model. Results: The incidence of new dyslipidemia during the follow-up period was 78.4% (192 patients), and 11.9 per 100 person-years. Mean duration from menopause to developing dyslipidemia was 5.3 years in new dyslipidemia cases. The triglyceride/high density lipoprotein (TG/HDL-C) ratio at baseline (hazard ratio = 2.20; 95% confidence interval = 1.39~3.48) was independently associated with developing dyslipidemia. Conclusion: Dyslipidemia occurs frequently in postmenopausal women, principally within five years after menopause. Therefore, steps must be taken to prevent dyslipidemia immediately after menopause, particularly in women with a high TG/HDL-C ratio at the start of menopause.
Keywords
Dyslipidemias; Incidence; Menopause; Risk Factors;
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