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http://dx.doi.org/10.4040/jkan.2014.44.1.108

Factors Influencing Quality of Life in Patients with Breast Cancer on Hormone Therapy  

Hwang, Eunkyung (Seoul National University Hospital)
Yi, Myungsun (College of Nursing, Research Institute of Nursing Science, Seoul National University)
Publication Information
Journal of Korean Academy of Nursing / v.44, no.1, 2014 , pp. 108-117 More about this Journal
Abstract
Purpose: The purpose of the study was to identify degrees of pain, menopause symptoms, and quality of life, and to identify factors influencing quality of life of patients with breast cancer who were on hormone therapy. Methods: A cross-sectional survey design was utilized. Data were collected using questionnaires from 110 patients with breast cancer who had been on hormone therapy for 3 months or more and were being treated at a university hospital in Seoul. Data were analyzed using ${\chi}^2$-test, t-test, ANOVA, Pearson correlation coefficient and multiple linear regression. Results: Mean age of the participants was 53.56 (SD=6.67) and 54 (51.4%) had stage 0 or I at the time of diagnosis. Most of the participants reported having pain and menopause symptoms (88.2% and 95.5% respectively). The mean score for quality of life was $87.84{\pm}21.17$. Pain, menopause symptoms and quality of life had strong correlations with each other (p<.005). Quality of life was explained by menopause symptoms (${\beta}$= -.71), economic status (${\beta}$=.20) and occupation (${\beta}$=.16). Conclusion: The results of the study suggest that menopause symptoms should be incorporated into oncologic nursing care to improve quality of life of patients with breast cancer on hormone therapy.
Keywords
Breast neoplasms; Hormornal antineoplastic agents; Quality of life; Pain; Menopause;
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1 Lee JH. The association of obesity indices and cardiovascular risk in Korean type 2 diabetes. The Korean Journal of Obesity. 2013;22(4):212-214. http://dx.doi.org/10.7570/kjo.2013.22.4.212   DOI
2 Park JH, Jun EY, Kang MY, Joung YS, Kim GS. Symptom experience and quality of life in breast cancer survivors. Journal of Korean Academy of Nursing. 2009;39(5):613-621. http://dx.doi.org/10.4040/jkan.2009.39.5.613   DOI
3 Otte JL, Carpenter JS, Zhong X, Johnstone PA. Feasibility study of acupuncture for reducing sleep disturbances and hot flashes in postmenopausal breast cancer survivors. Clinical Nurse Specialist CNS. 2011; 25(5):228-236. http://dx.doi.org/10.1097/NUR.0b013e318229950b   DOI
4 Carson JW, Carson KM, Porter LS, Keefe FJ, Seewaldt VL. Yoga of awareness program for menopausal symptoms in breast cancer survivors: Results from a randomized trial. Supportive Care in Cancer. 2009;17(10):1301-1309. http://dx.doi.org/10.1007/s00520-009-0587-5   DOI   ScienceOn
5 Toulis KA, Tzellos T, Kouvelas D, Goulis DG. Gabapentin for the treatment of hot flashes in women with natural or tamoxifen-induced menopause: A systematic review and meta-analysis. Clinical Therapeutics. 2009;31(2):221-235. http://dx.doi.org/10.1016/j.clinthera.2009.02.006   DOI
6 Park J. Symptom cluster and status of physical function in women with breast cancer receiving chemotheraopy [master's thesis]. Seoul: Seoul National University; 2009.
7 Park H, Yoon HG. Menopausal symptoms, sexual function, depression, and quality of life in Korean patients with breast cancer receiving chemotherapy. Supportive Care in Cancer. 2013;21(9):2499-2507. http://dx.doi.org/10.1007/s00520-013-1815-6   DOI
8 Kwon EJ, Yi M. Distress and quality of life in breast cancer survivors in Korea. Asian Oncology Nursing. 2012;12(4):289-296. http://dx.doi.org/10.5388/aon.2012.12.4.289   DOI   ScienceOn
9 Hwang SY. Factors affecting quality of life among breast cancer survivors. Mental Health & Social Work. 2009;33:257-287.
10 Mao JJ, Stricker C, Bruner D, Xie S, Bowman MA, Farrar JT, et al. Patterns and risk factors associated with aromatase inhibitor-related arthralgia among breast cancer survivors. Cancer. 2009;115(16):3631-3639. http://dx.doi.org/10.1002/cncr.24419   DOI   ScienceOn
11 Yun YH, Mendoza TR, Heo DS, Yoo T, Heo BY, Park HA, et al. Development of a cancer pain assessment tool in Korea: A validation study of a Korean version of the brief pain inventory. Oncology. 2004;66(6):439-444. http://dx.doi.org/10.1159/000079497   DOI   ScienceOn
12 Faul F, Erdfelder E, Buchner A, Lang AG. Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses. Behavior Research Methods. 2009;41(4):1149-1160. http://dx.doi.org/10.3758/brm.41.4.1149   DOI   ScienceOn
13 Cella DF, Tulsky DS, Gray G, Sarafian B, Linn E, Bonomi A, et al. The functional assessment of cancer therapy scale: Development and validation of the general measure. Journal of Clinical Oncology. 1993;11(3): 570-579.   DOI
14 Heinemann K, Ruebig A, Potthoff P, Schneider HP, Strelow F, Heinemann LA, et al. The menopause rating scale (MRS) scale: A methodological review. Health and Quality of Life Outcomes. 2004;2:45. http://dx.doi.org/10.1186/1477-7525-2-45   DOI   ScienceOn
15 Yoo HJ, Ahn SH, Eremenco S, Kim H, Kim WK, Kim SB, et al. Korean translation and validation of the functional assessment of cancer therapy- breast (FACT-B) scale version 4. Quality of Life Research. 2005;14 (6):1627-1632.   DOI   ScienceOn
16 Cleeland CS, Ryan KM. Pain assessment: Global use of the brief pain inventory. Annals of the Academy of Medicine Singapore. 1994;23(2): 129-138.
17 Serlin RC, Mendoza TR, Nakamura Y, Edwards KR, Cleeland CS. When is cancer pain mild, moderate or severe? Grading pain severity by its interference with function. Pain. 1995;61(2):277-284.   DOI   ScienceOn
18 Reimer T, Gerber B. Quality-of-life considerations in the treatment of early-stage breast cancer in the elderly. Drugs and Aging. 2010;27(10): 791-800. http://dx.doi.org/10.2165/11584700-000000000-00000   DOI
19 Safarinejad MR, Shafiei N, Safarinejad S. Quality of life and sexual functioning in young women with early-stage breast cancer 1 year after lumpectomy. Psycho-Oncology. 2013;22(6):1242-1248. http://dx.doi.org/10.1002/pon.3130   DOI
20 Fenlon DR, Corner JL, Haviland J. Menopausal hot flushes after breast cancer. European Journal of Cancer Care. 2009;18(2):140-148. http://dx.doi.org/10.1111/j.1365-2354.2007.00902.x   DOI
21 Seo HJ. A comparison of the cancer incidence rates between KCCR's registered cancer statistics and NHIC's data of insurance claims [master's thesis]. Seoul: Korea University; 2012.
22 Oberguggenberger A, Hubalek M, Sztankay M, Meraner V, Beer B, Oberacher H, et al. Is the toxicity of adjuvant aromatase inhibitor therapy underestimated? Complementary information from patient-reported outcomes (PROs). Breast Cancer Research and Treatment. 2011;128(2):553-561. http://dx.doi.org/10.1007/s10549-011-1378-5   DOI
23 Korean Breast Cancer Society. The breast. 2nd ed. Seoul: Ilchokak Publishing Co.; 2005.
24 Dorjgochoo T, Gu K, Kallianpur A, Zheng Y, Zheng W, Chen Z, et al. Menopausal symptoms among breast cancer patients 6 months after diagnosis: A report from the Shanghai breast cancer survival study. Menopause (New York, NY). 2009;16(6):1205-1212. http://dx.doi.org/10.1097/gme.0b013e3181aac32b   DOI
25 Patterson RE, Saquib N, Natarajan L, Rock CL, Parker BA, Thomson CA, et al. Improvement in self-reported physical health predicts longer survival among women with a history of breast cancer. Breast Cancer Research and Treatment. 2011;127(2):541-547. http://dx.doi.org/10.1007/s10549-010-1236-x   DOI
26 Fontaine C, Meulemans A, Huizing M, Collen C, Kaufman L, De Mey J, et al. Tolerance of adjuvant letrozole outside of clinical trials. Breast (Edinburgh, Scotland). 2008;17(4):376-381. http://dx.doi.org/10.1016/j.breast.2008.02.006   DOI
27 Davies C, Godwin J, Gray R, Clarke M, Cutter D, Darby S, et al. Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: Patient-level meta-analysis of randomised trials. Lancet. 2011;378(9793):771-784. http://dx.doi.org/10.1016/s0140-6736(11)60993-8   DOI   ScienceOn