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The Analysis of Intervention Studies for Patients with Metabolic Syndrome  

Oh, Eui-Geum (College of Nursing, Nursing Policy Research Institution, Yonsei University)
Kim, Soo-Hyun (College of Nursing, Yonsei University)
Hyun, Sa-Sang (College of Nursing, Yonsei University)
Kang, Myung-Sook (College of Nursing, Yonsei University)
Bang, So-Youn (College of Nursing, Yonyei University)
Publication Information
Journal of Korean Academy of Nursing / v.37, no.1, 2007 , pp. 72-80 More about this Journal
Abstract
Purpose: This study was to analyze the trend of research on intervention for patients with metabolic syndrome. Method: Using Pubmed, Medline, and CINAHL search engines, a randomized controlled trial(RCT) researching titles such as 'metabolic syndrome', 'intervention', 'lifestyle modification', or 'community-based' were collected. A total of 16 researches were analyzed based on the guidelines of the National Cholesterol Education Program - Adult Treatment Panel(NCEP-ATP III). Results: 1) The total period of the intervention was from 12 to 24 weeks, the frequency was 3 to 5 times per week, and the duration of each session was from 45 to 60 minutes. The types of intervention included exercise, diet, and medication. Among these types, diet was performed most frequently. 2) The outcomes of the intervention was measured with physical aspects such as anthropometric measures, body composition, or biological markers. No studies have evaluated psychosocial outcomes such as quality of life. 3) In terms of effectiveness of the intervention, anthropometric indicators, body composition, or serological markers showed positive effects, whereas results on endothelial or urine indicators were inconsistent. Conclusion: Methodological research developing comprehensive therapeutic lifestyle modification programs and intervention studies are needed for patients with metabolic syndrome. In addition, effects should be evaluated with multidimensional perspectives.
Keywords
Analysis; Intervention studies; Metabolic syndrome;
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1 Ford, E. S., Giles, W. H., & Dietz, W. H. (2002). Prevalence of the metabolic syndrome among US adults: Findings from the third national health and nutrition examination survey. J Am Med Assoc, 287, 356-359   DOI   ScienceOn
2 Poppitt, S. D., Keogh, G. F., Prentice, A. M., Williams, D. E., Sonnemans, H. M., Valk, E. E., Robinson, E., & Wareham, N. J. (2002). Long-term effects of ad libitum low-fat, high-carbohydrate diets on body weight and serum lipids in overweight subjects with metabolic syndrome. Am J Clin Nutr, 75, 11-20   DOI   PUBMED
3 Stern, L., Iqbal, N., Seshadri, P., Chicano, K. L., Daily, D. A., McGrory, J., Williams, M., Gracely, E. J., & Samaha, F. F. (2004). The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: one-year follow-up of a randomized trial. Ann Intern Med, 140, 778-785   DOI   ScienceOn
4 Stewart, K. J., Bacher, A. C., Turner, K., Lim, J. G., Hees, P. S., Shapiro, E. P., Tayback, M., & Ouyang, P. (2005). Exercise and risk factors associated with metabolic syndrome in older adults. Am J Prev Med, 28, 9-18   DOI   ScienceOn
5 Troseid, M., Lappegard, K. T., Claudi, T., Damas, J. K., Morkrid, L., Brendberg, R., & Mollnes, T. E. (2004). Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome. Eur Heart J, 25, 349-355   DOI   ScienceOn
6 Albert, K. G., & Zimmet, P. Z. (1998). Definition, diagnosis, and classification of diabetes mellitus and its complication. Part 1: diagnosis and classification of diabetes mellitus provisional report of WHO consultation. Diabet Med, 15, 539-553   DOI   ScienceOn
7 Azadbakht, L., Mirmiran, P., Esmaillzadeh, A., Azizi, T., & Azizi, F. (2005). Beneficial effects of a dietary approaches to stop hypertension eating plan on features of the metabolic syndrome. Diabetes Care, 28, 2823-2831   DOI   ScienceOn
8 Noakes, M., Foster, P. R., Keogh, J. B., & Clifton, P. M. (2004). Meal replacements are as effective as structured weight-loss diets for treating obesity in adults with features of metabolic syndrome. J Nutr, 134, 1894-1899
9 Troseid, M., Lappegard, K. T., Mollnes, T. E., Arnesen, R., & Seljeflot, I. (2005). Changes in serum levels of E-selectin correlate to improved glycaemic control and reduced obesity in subjects with the metabolic syndrome. Scand J Clin Lab Invest, 65, 283-290   DOI   ScienceOn
10 Balkau, B., & Charles, M. A. (1999). Comment on the provisional report from the WHO consultation. European Group for the Study of Insulin Resistance (EGIR). Diabet Med, 16, 442-443   DOI   ScienceOn
11 Athyros, V. G., Mikhailidis, D. P., Papageorgiou, A. A., Didangelos, T. P., Peletidou, A., Kleta, D., Karagiannis, A., Kakafika, A. I., Tziomalos, K., & Elisaf, M. (2005). Targeting vascular risk in patients with metabolic syndrome but without diabetes. Metabolism, 54, 1065-1074   DOI   ScienceOn
12 Kim, E. S., Han, S. M., Kim, Y. I., Song, K. H., Kim, M. S., Kim, W. B., Park, J. Y., & Lee, K. U. (2004). Prevalence and clinical characteristics of metabolic syndrome in a rural population of South Korea. Diabet Med, 21, 1141-1143   DOI   ScienceOn
13 National Institutes of Health: third report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of high blood cholesterol in adults (Adult Treatment Panel III). (2001). Executive summary. Bethesda, Md: National Institute of Health, National Heart, Lung, Blood Institute, (NIH Publication no. 01-3670)
14 Grundy, S. M., Cleeman, J. I., Merz, C. N., Brewer, H. B. Jr., Clark, L. T., Hunninghake, D. B., Pasternak, R. C., Smith, S. C. Jr., & Stone, N. J.; National Heart, Lung, and Blood Institute; American College of Cardiology Foundation; American Heart Association. (2004). Implication of recent clinical trials for the national cholesterol education program adult treatment panel III guideline. Circulation, 110, 227-239   DOI   ScienceOn
15 Kim, H. S. (2003). Effects of behavioral modification of obesity index, skinfold thickness, body fat, serum lipids in obese school children. J Korean Acad Nur, 33(3), 405-413   과학기술학회마을   DOI
16 Wien, M. A., Sabate, J. M., Ikle, D. N., Cole, S. E., & Kandeel, F. R. (2003). Almonds vs complex carbohydrates in a weight reduction program. Int J Obes Relat Metab Disord, 27, 1365-1372   DOI   ScienceOn
17 Kukkonen-Harjula, K. T., Borg, P. T., Nenonen, A. M., & Fogelholm, M. G. (2005). Effects of a weight maintenance program with or without exercise on the metabolic syndrome: a randomized trial in obese men. Prev Med, 41, 784-790   DOI   ScienceOn
18 Reseland, J. E., Anderssen, S. A., Solvoll, K., Hjermann, I., Urdal, P., Holme, I., & Drevon, C. A. (2001). Effect of long-term changes in diet and exercise on plasma leptin concentrations. Am J Clin Nutr, 73, 240-245   DOI   PUBMED
19 Kim, Y., Suh, Y. K., & Choi, H. (2004). BMI and metabolic disorders in South Korean adults: 1998 Korea National Health and Nutrition Survey. Obes Res, 12(3), 442-453   DOI   ScienceOn
20 National Cholesterol Education Program. (2002). Third report of the expert panel of detection, evaluation, and treatment of high blood cholesterol in adults (Adults Treatment Panel III). NIH Pub. No. 02-5215. Bethesda, MD: National Heart, Lung, and Blood Institute
21 Laaksonen, D. E., Nuutinen, J., Lahtinen, T., Rissanen, A., & Niskanen, L. K. (2003). Changes in abdominal subcutaneous fat water content with rapid weight loss and long-term weight maintenance in abdominally obese men and women. Int J Obes Relat Metab Disord, 27, 677-683   DOI   ScienceOn
22 Hittel, D. S., Kraus, W. E., Tanner, C. J., Houmard, J. A., & Hoffman, E. P. (2005). Exercise training increases electron and substrate shuttling proteins in muscle of overweight men and women with the metabolic syndrome. J Appl Physiol, 98, 168-179   DOI   ScienceOn
23 Park, H. S., Sim, S. J., & Park, J. Y. (2004). Effect of weight reduction on metabolic syndrome in Korean obese patients. J Korean Med Sci, 19, 202-208   DOI   PUBMED   ScienceOn
24 Nashar, K., Nguyen, J. P., Jesri, A., Morrow, J. D., & Egan, B. M. (2004). Angiotensin receptor blockade improves arterial distensibility and reduces exercise-induced pressor responses in obese hypertensive patients with the metabolic syndrome. Am J Hypertens, 17, 477-482   DOI   ScienceOn
25 Yoon, S. Y., Oh, S. W., Baik, H. W., Park, H. S., & Kim, W. Y. (2004). Alcohol consumption and the metabolic syndrome in Korean adults: the 1998 Korean National Health and Nutrition Examination Survey. Am J Clin Nutr, 80, 217-224   DOI   PUBMED
26 Geluk, C. A., Asselbergs, F. W., Hillege, H. L., Bakker, S. J., de Jong, P. E., Zijlstra, F., & van Gilst, W. H. (2005). Impact of statinsin microalbuminuric subjects with the metabolic syndrome: a sub study of the PREVEND Intervention Trial. Eur Heart J, 26, 1314-1320   DOI   ScienceOn