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http://dx.doi.org/10.3795/KSME-B.2012.36.11.1111

Design and Fabrication of Nasal-Implant-Shaped Scaffold and Regeneration of Nasal Cartilage Tissue for Rhinoplasty  

Jung, Jin-Woo (Dept. of Mechanical Engineering, POSTECH)
Jang, Jin-Ah (Integrative Biosciences and Biotechnology, POSTECH)
Shim, Jin-Hyung (Dept. of Mechanical Engineering, POSTECH)
Kim, Sung-Won (Dept. of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic Univ. of Korea)
Cho, Dong-Woo (Dept. of Mechanical Engineering, POSTECH)
Publication Information
Transactions of the Korean Society of Mechanical Engineers B / v.36, no.11, 2012 , pp. 1111-1117 More about this Journal
Abstract
Implants for rhinoplasty should ideally be biocompatible and possess long-term stability after implantation. Silicone implants are most widely used for rhinoplasty. However, these implants suffer from problems related to high extrusion and infection rates. To minimize these complications, we propose a novel augmentation rhinoplasty technique using tissue engineering. To demonstrate its feasibility, a nasal-implant-shaped scaffold was designed using commercialized CAD software and fabricated using a Multi-head Deposition System, which is a solid freeform fabrication system that dispenses material. In vitro cell proliferation and chondrogenic differentiation tests were carried out using nasal septal chondrocytes.
Keywords
Rhinoplasty; Tissue Engineering; Solid Freeform Fabrication;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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