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http://dx.doi.org/10.3795/KSME-B.2011.35.7.685

Electrocardiogram-Gated Multi-Angle Doppler Optical Coherence Tomography  

Ahn, Yeh-Chan (Dept. of Biomedical Engineering, Pukyong Nat'l Univ.)
Publication Information
Transactions of the Korean Society of Mechanical Engineers B / v.35, no.7, 2011 , pp. 685-691 More about this Journal
Abstract
The aim of this study is to point out the uniqueness of Doppler optical coherence tomography (DOCT) for use in a probe station for (in vivo) visualization of microscale flow and structure and to maximize the effectiveness of DOCT by overcoming its limitations. Conventional DOCT produces images of only one of the velocity components that is parallel to the incident light. In this study, a multi-angle DOCT to quantify a velocity vector field is proposed; this is an extension from a velocity scalar field to a vector field. Quantifying an instantaneous three-dimensional velocity field in a pulsating flow is another challenge because of its limited frame rate. The in-vivo pulsating blood flow is measured by using an electrocardiogram-gated multi-angle DOCT in a hamster cheek pouch model. It is shown that the aliasing problem caused by a relatively low frame rate is resolved by using this method of measurement.
Keywords
Doppler Optical Coherence Tomography; In Vivo Blood Flow Imaging; Pulsating Flow; Measurement of Velocity Vector Field;
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